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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19 Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	38990941	D112A	NSP8	ORF1a			View
2	38990941	R111A	NSP8	ORF1a			View
3	38990941	L372F	NSP8	ORF1a			View
4	38990941	L372P	NSP8	ORF1a			View
5	38990941	L527H	NSP8	ORF1a			View
6	38990941	P323L	NSP8	ORF1a			View
7	38990941	V373A	NSP8	ORF1a			View
8	36512569	A12162G	NSP8	ORF1a		G R L	View
9	36512569	Q24R	NSP8	ORF1a		G R L	View
10	38534781	P133S	NSP8	ORF1a		R	View
11	38534781	Q24H	NSP8	ORF1a		R	View
12	38534781	T89I	NSP8	ORF1a		R	View
13	38534781	T141M	NSP8	ORF1a		R	View
14	38534781	T145I	NSP8	ORF1a		R	View
15	38534781	Q24R	NSP8	ORF1a		R	View
16	38534781	T123I	NSP8	ORF1a		R	View
17	38534781	N118S	NSP8	ORF1a		R	View
18	38534781	T148I	NSP8	ORF1a		R	View
19	38534781	T187I	NSP8	ORF1a		R	View
20	38534781	S76P	NSP8	ORF1a		R	View
21	38534781	S76G	NSP8	ORF1a		R	View
22	38534781	S76N	NSP8	ORF1a		R	View
23	38534781	S76D	NSP8	ORF1a		R	View
24	38534781	S76M	NSP8	ORF1a		R	View
25	38534781	S76Q	NSP8	ORF1a		R	View
26	38534781	S76K	NSP8	ORF1a		R	View
27	38534781	S76H	NSP8	ORF1a		R	View
28	38534781	S76T	NSP8	ORF1a		R	View
29	38534781	S76V	NSP8	ORF1a		R	View
30	38534781	S76E	NSP8	ORF1a		R	View
31	38534781	S76L	NSP8	ORF1a		R	View
32	38534781	S76F	NSP8	ORF1a		R	View
33	38534781	S76A	NSP8	ORF1a		R	View
34	38534781	S76W	NSP8	ORF1a		R	View
35	38534781	S76R	NSP8	ORF1a		R	View
36	38534781	S76I	NSP8	ORF1a		R	View
37	38534781	S76C	NSP8	ORF1a		R	View
38	38534781	S76Y	NSP8	ORF1a		R	View
39	38534781	L122G	NSP8	ORF1a		R	View
40	38534781	L122H	NSP8	ORF1a		R	View
41	38534781	L122D	NSP8	ORF1a		R	View
42	38534781	L122A	NSP8	ORF1a		R	View
43	38534781	L122E	NSP8	ORF1a		R	View
44	38534781	L122N	NSP8	ORF1a		R	View
45	38534781	L122C	NSP8	ORF1a		R	View
46	38534781	L122T	NSP8	ORF1a		R	View
47	38534781	L122P	NSP8	ORF1a		R	View
48	38534781	L122S	NSP8	ORF1a		R	View
49	38534781	L122K	NSP8	ORF1a		R	View
50	38534781	L122V	NSP8	ORF1a		R	View
51	38534781	L122M	NSP8	ORF1a		R	View
52	38534781	L122II	NSP8	ORF1a		R	View
53	38534781	L122Q	NSP8	ORF1a		R	View
54	38534781	L122F	NSP8	ORF1a		R	View
55	38534781	L122R	NSP8	ORF1a		R	View
56	38534781	L122Y	NSP8	ORF1a		R	View
57	38534781	L122W	NSP8	ORF1a		R	View
58	38534781	P121G	NSP8	ORF1a		R	View
59	38534781	P121D	NSP8	ORF1a		R	View
60	38534781	P121T	NSP8	ORF1a		R	View
61	38534781	P121S	NSP8	ORF1a		R	View
62	38534781	P121N	NSP8	ORF1a		R	View
63	38534781	P121R	NSP8	ORF1a		R	View
64	38534781	P121C	NSP8	ORF1a		R	View
65	38534781	P121E	NSP8	ORF1a		R	View
66	38534781	P121Q	NSP8	ORF1a		R	View
67	38534781	F92A	NSP8	ORF1a		R	View
68	38534781	M90A	NSP8	ORF1a		R	View
69	38534781	M94A	NSP8	ORF1a		R	View
70	35271728	C12525T	NSP8	ORF1a	COVID-19	G R L	View
71	35271728	T145I	NSP8	ORF1a	COVID-19	G R L	View
72	38605705	G12111A	NSP8	ORF1a	COVID-19	G R S C L	View
73	38605705	S7N	NSP8	ORF1a	COVID-19	G R S C L	View
74	37224159	A12140G	NSP8	ORF1a	COVID-19	G R L	View
75	37224159	A12444G	NSP8	ORF1a	COVID-19	G R L	View
76	37224159	N118S	NSP8	ORF1a	COVID-19	G R L	View
77	37224159	T17A	NSP8	ORF1a	COVID-19	G R L	View
78	37243279	Y138H	NSP8	ORF1a	COVID-19	G R S C L	View
79	36778569	S41F	NSP8	ORF1a	COVID-19	G R S L	View
80	35992703	A18T	NSP8	ORF1a	COVID-19	G L	View
81	35992703	D101A	NSP8	ORF1a	COVID-19	G L	View
82	38605705	G12160A	NSP8	ORF1a	COVID-19	G R S C L	View
83	38605705	G12310A	NSP8	ORF1a	COVID-19	G R S C L	View
84	39145418	A21V	NSP8	ORF1a	COVID-19		View
85	39145418	M129I	NSP8	ORF1a	COVID-19		View
86	39145418	Q24R	NSP8	ORF1a	COVID-19		View
87	39145418	T141M	NSP8	ORF1a	COVID-19		View
88	36008511	T4090I	NSP8	ORF1a	COVID-19	R C L	View
89	36090111	N3937N	NSP8	ORF1a	COVID-19	R C L	View
90	36841805	Q24R	NSP8	ORF1a	COVID-19	R	View
91	35913920	L84S	NSP8	ORF1a	COVID-19	R	View
92	35913920	Q27X	NSP8	ORF1a	COVID-19	R	View
93	35913920	S24L	NSP8	ORF1a	COVID-19	R	View
94	35891618	W182R	NSP8	ORF1a	COVID-19	S L	View
95	37529147	E23E	NSP8	ORF1a	COVID-19	R S L	View
96	37529147	Q73Q	NSP8	ORF1a	COVID-19	R S L	View
97	40082784	T145I	NSP8	ORF1a	COVID-19	S L	View
98	38276171	M55I	NSP8	ORF1a	COVID-19	R S L	View
99	38276171	T148I	NSP8	ORF1a	COVID-19	R S L	View