All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: NTD
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39827186 A264D
NTD
S
Cell line
I
View
2 39470577 D215G
NTD
S
Cell line
S
I
View
3 39470577 D80A
NTD
S
Cell line
S
I
View
4 39470577 S32L
NTD
S
Cell line
S
View
5 37243229 H146Q
NTD
S
COVID-19
G
S
View
6 37243229 Q183E
NTD
S
COVID-19
G
S
View
7 37243229 V213E
NTD
S
COVID-19
G
S
View
8 37243229 V83A
NTD
S
COVID-19
G
S
View
9 35396511 242delL
NTD
S

G
R
L
View
10 35931073 A67V
NTD
S

R
L
View
11 35931073 L212I
NTD
S

R
L
View
12 35931073 T95I
NTD
S

R
L
View
13 35258772 A67V
NTD
S
COVID-19
G
View
14 35258772 T95I
NTD
S
COVID-19
G
View
15 35258772 L212I
NTD
S
COVID-19
G
View
16 37631999 A67V
NTD
S
COVID-19
R
S
I
L
View
17 39653699 P80R
NTD
S
COVID-19
G
R
View
18 37631999 T95I
NTD
S
COVID-19
G
R
S
L
View
19 39653699 D63G
NTD
S
COVID-19
G
R
View
20 37631999 T19R
NTD
S
COVID-19
G
R
S
L
View
21 34210893 W152C
NTD
S
COVID-19
G
View
22 36535326 144delY
NTD
S
COVID-19
G
S
View
23 39653699 A119S
NTD
S
COVID-19
G
R
View
24 39653699 E136D
NTD
S
COVID-19
G
R
View
25 39653699 P151S
NTD
S
COVID-19
G
R
View
26 37224159 E210V
NTD
S
COVID-19
G
R
L
View
27 37301830 G142D
NTD
S
COVID-19
G
R
S
I
C
L
View
28 37270625 S254F
NTD
S
COVID-19
G
R
S
C
L
View
29 39653699 P67S
NTD
S
COVID-19
G
R
View
30 39720734 Y145D
NTD
S
COVID-19
G
View
31 37631999 A27S
NTD
S
COVID-19
G
R
S
L
View
32 36224497 L18F
NTD
S
COVID-19
G
I
View
33 36224497 242_244del
NTD
S
COVID-19
G
I
View
34 36224497 69_70del
NTD
S
COVID-19
G
I
View
35 36224497 144del
NTD
S
COVID-19
G
I
View
36 37631999 G142D
NTD
S
COVID-19
G
R
S
I
L
View
37 38791536 L54F
NTD
S
COVID-19
R
L
View
38 38791536 R158G
NTD
S
COVID-19
R
L
View
39 38791536 V227I
NTD
S
COVID-19
R
L
View
40 39653699 F171G
NTD
S
COVID-19
R
View
41 39653699 Q58I
NTD
S
COVID-19
R
View
42 39653699 R107A
NTD
S
COVID-19
R
View
43 39653699 S105I
NTD
S
COVID-19
R
View
44 39653699 W108G
NTD
S
COVID-19
R
View
45 39653699 Y109A
NTD
S
COVID-19
R
View
46 36560780 L176F
NTD
S
COVID-19
View
47 36733340 G181V
NTD
S
COVID-19
R
L
View
48 36733340 R102S
NTD
S
COVID-19
R
L
View
49 37631999 V70F
NTD
S
COVID-19
R
S
I
L
View
50 37631999 211del
NTD
S
COVID-19
R
S
I
L
View
51 37631999 214insEPE
NTD
S
COVID-19
R
S
I
L
View
52 37631999 K77T
NTD
S
COVID-19
R
S
L
View
53 37631999 R158G
NTD
S
COVID-19
R
S
L
View
54 37631999 A222V
NTD
S
COVID-19
R
S
L
View
55 37631999 A262S
NTD
S
COVID-19
R
S
L
View
56 37631999 E154K
NTD
S
COVID-19
R
S
L
View
57 37631999 H49Y
NTD
S
COVID-19
R
S
L
View
58 37631999 L18F
NTD
S
COVID-19
R
S
L
View
59 37631999 L5F
NTD
S
COVID-19
R
S
L
View
60 37631999 Q14H
NTD
S
COVID-19
R
S
L
View
61 37631999 T19I
NTD
S
COVID-19
R
S
L
View
62 37631999 V213G
NTD
S
COVID-19
R
S
L
View
63 37631999 Y145D
NTD
S
COVID-19
R
S
L
View
64 37849762 W152R
NTD
S
COVID-19
R
S
L
View
65 37903828 L10S
NTD
S
COVID-19
R
View
66 37903828 L5Y
NTD
S
COVID-19
R
View
67 37903828 P26L
NTD
S
COVID-19
R
View
68 37903828 S13L
NTD
S
COVID-19
R
View
69 37903828 S60A
NTD
S
COVID-19
R
View
70 37903828 T19R
NTD
S
COVID-19
R
View
71 37903828 V3L
NTD
S
COVID-19
R
View
72 38090396 E154K
NTD
S
COVID-19
R
C
L
View
73 38090396 G142D
NTD
S
COVID-19
R
C
L
View
74 38090396 T95I
NTD
S
COVID-19
R
C
L
View
75 36362544 D111N
NTD
S
COVID-19
C
L
View
76 36362544 D228N
NTD
S
COVID-19
C
L
View
77 36362544 E224K
NTD
S
COVID-19
C
L
View
78 36362544 Q115H
NTD
S
COVID-19
C
L
View
79 39470577 144delY
NTD
S
Cell line
G
S
I
View
80 38048640 R190S
NTD
S
Cell line
G
R
S
View
81 38048640 T20N
NTD
S
Cell line
G
R
S
View
82 36590900 T19R
NTD
S
Cell line
G
View
83 36590900 G142D
NTD
S
Cell line
G
View
84 36590900 R158G
NTD
S
Cell line
G
View
85 36590900 156delE
NTD
S
Cell line
G
View
86 36590900 157delE
NTD
S
Cell line
G
View
87 36590900 T95I
NTD
S
Cell line
G
View
88 39470577 A27S
NTD
S
Cell line
G
S
View
89 39470577 G142D
NTD
S
Cell line
G
S
View
90 39470577 T19I
NTD
S
Cell line
G
S
View
91 39470577 V213G
NTD
S
Cell line
G
S
View
92 39827186 144delY
NTD
S
Cell line
G
I
View
93 39827186 F157S
NTD
S
Cell line
G
I
View
94 39827186 H245N
NTD
S
Cell line
G
I
View
95 39827186 R158G
NTD
S
Cell line
G
I
View
96 39827186 V16insMPLF
NTD
S
Cell line
G
I
View
97 38793644 D215A
NTD
S
Cell line
L
View
98 38793644 R78Q
NTD
S
Cell line
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.