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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19 Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	35989365	P323L	ORF1b	ORF1b		G	View
2	35989365	I42V	ORF1b	ORF1b		G	View
3	35551247	K829R	ORF1b	ORF1b		G L	View
4	35551247	K82R	ORF1b	ORF1b		G L	View
5	35710544	P314L	ORF1b	ORF1b		G R L	View
6	35632749	A2143V	ORF1b	ORF1b		G R L	View
7	35632749	L1701F	ORF1b	ORF1b		G R L	View
8	35632749	P1000L	ORF1b	ORF1b		G R L	View
9	35255849	P1936S	ORF1b	ORF1b		L	View
10	35538074	D708A	ORF1b	ORF1b		R I C	View
11	35538074	I2568X	ORF1b	ORF1b		R I C	View
12	35538074	K709X	ORF1b	ORF1b		R I C	View
13	35538074	L714X	ORF1b	ORF1b		R I C	View
14	35538074	P1000L	ORF1b	ORF1b		R I C	View
15	35538074	P314L	ORF1b	ORF1b		R I C	View
16	35538074	R712X	ORF1b	ORF1b		R I C	View
17	35538074	S598I	ORF1b	ORF1b		R I C	View
18	35538074	V711D	ORF1b	ORF1b		R I C	View
19	35538074	V711E	ORF1b	ORF1b		R I C	View
20	35538074	V711X	ORF1b	ORF1b		R I C	View
21	35538074	Y710L	ORF1b	ORF1b		R I C	View
22	35538074	Y710X	ORF1b	ORF1b		R I C	View
23	35658876	V2354F	ORF1b	ORF1b		S L	View
24	35710544	S1182L	ORF1b	ORF1b		R L	View
25	35831773	P314L	ORF1b	ORF1b		L	View
26	35658876	V226L	ORF1b	ORF1b		S L	View
27	36296228	K2557R	ORF1b	ORF1b	COVID-19	G S C L	View
28	36755883	P314L	ORF1b	ORF1b	COVID-19	G R L	View
29	36755883	G662S	ORF1b	ORF1b	COVID-19	G R L	View
30	36755883	R1315C	ORF1b	ORF1b	COVID-19	G R L	View
31	36755883	I1566V	ORF1b	ORF1b	COVID-19	G R L	View
32	36755883	T2163I	ORF1b	ORF1b	COVID-19	G R L	View
33	37965255	S997P	ORF1b	ORF1b	COVID-19	G R C L	View
34	37965255	I2664V	ORF1b	ORF1b	COVID-19	G R C L	View
35	37965255	T2432I	ORF1b	ORF1b	COVID-19	G R C L	View
36	37965255	Y1648C	ORF1b	ORF1b	COVID-19	G R C L	View
37	37965255	I1566V	ORF1b	ORF1b	COVID-19	G R C L	View
38	37965255	P314L	ORF1b	ORF1b	COVID-19	G R C L	View
39	37965255	R1315C	ORF1b	ORF1b	COVID-19	G R C L	View
40	38763300	P1223L	ORF1b	ORF1b	COVID-19	G R S L	View
41	38763300	R1315C	ORF1b	ORF1b	COVID-19	G R S L	View
42	38763300	T2163I	ORF1b	ORF1b	COVID-19	G R S L	View
43	37435034	E1084D	ORF1b	ORF1b	COVID-19	G R C L	View
44	37435034	P314L	ORF1b	ORF1b	COVID-19	G R C L	View
45	37435034	V1883T	ORF1b	ORF1b	COVID-19	G R C L	View
46	39604601	A1918V	ORF1b	ORF1b	COVID-19	G L	View
47	39604601	H2285Y	ORF1b	ORF1b	COVID-19	G L	View
48	39604601	T40I	ORF1b	ORF1b	COVID-19	G L	View
49	40006937	A1918V	ORF1b	ORF1b	COVID-19	G S L	View
50	40006937	G662S	ORF1b	ORF1b	COVID-19	G S L	View
51	40006937	P1000L	ORF1b	ORF1b	COVID-19	G S L	View
52	36310647	A1779V	ORF1b	ORF1b	COVID-19	G R S	View
53	36310647	A942V	ORF1b	ORF1b	COVID-19	G R S	View
54	36310647	K2097T	ORF1b	ORF1b	COVID-19	G R S	View
55	36786950	P313L	ORF1b	ORF1b	COVID-19	G R S C L	View
56	37376693	A18163G	ORF1b	ORF1b	COVID-19	G R S L	View
57	37376693	C16616A	ORF1b	ORF1b	COVID-19	G R S L	View
58	37376693	I1566V	ORF1b	ORF1b	COVID-19	G R S L	View
59	37376693	T1050N	ORF1b	ORF1b	COVID-19	G R S L	View
60	37058241	C14599T	ORF1b	ORF1b	COVID-19	G R S L	View
61	37376693	T2048I	ORF1b	ORF1b	COVID-19	G R S L	View
62	36310647	T591I	ORF1b	ORF1b	COVID-19	G R S	View
63	37376693	C15738T	ORF1b	ORF1b	COVID-19	G R S L	View
64	37376693	C17285T	ORF1b	ORF1b	COVID-19	G R S L	View
65	37376693	S1273L	ORF1b	ORF1b	COVID-19	G R S L	View
66	34634791	P314L	ORF1b	ORF1b	COVID-19	G R S	View
67	34634791	Q1011H	ORF1b	ORF1b	COVID-19	G R S	View
68	34634791	P314F	ORF1b	ORF1b	COVID-19	G R S	View
69	38791536	G2610N	ORF1b	ORF1b	COVID-19	G R L	View
70	38791536	I117L	ORF1b	ORF1b	COVID-19	G R L	View
71	36778569	P314L	ORF1b	ORF1b	COVID-19	G R S L	View
72	36310647	L1639V	ORF1b	ORF1b	COVID-19	G R S	View
73	40006937	P314L	ORF1b	ORF1b	COVID-19	G S L	View
74	39604601	H119R	ORF1b	ORF1b	COVID-19	G L	View
75	38601946	C14120T	ORF1b	ORF1b	COVID-19	G R C L	View
76	38601946	P218L	ORF1b	ORF1b	COVID-19	G R C L	View
77	32474553	P314L	ORF1b	ORF1b	COVID-19	G R	View
78	32641486	C14408T	ORF1b	ORF1b	COVID-19	G R S L	View
79	32641486	P314L	ORF1b	ORF1b	COVID-19	G R S L	View
80	38125422	C13730T	ORF1b	ORF1b	COVID-19	G R S C L	View
81	38125422	C13945T	ORF1b	ORF1b	COVID-19	G R S C L	View
82	38125422	C14408T	ORF1b	ORF1b	COVID-19	G R S C L	View
83	38125422	A14702G	ORF1b	ORF1b	COVID-19	G R S C L	View
84	38125422	G16636A	ORF1b	ORF1b	COVID-19	G R S C L	View
85	38125422	A18250G	ORF1b	ORF1b	COVID-19	G R S C L	View
86	38125422	G21073A	ORF1b	ORF1b	COVID-19	G R S C L	View
87	38125422	A21487G	ORF1b	ORF1b	COVID-19	G R S C L	View
88	38125422	A88V	ORF1b	ORF1b	COVID-19	G R S C L	View
89	38125422	P160S	ORF1b	ORF1b	COVID-19	G R S C L	View
90	38125422	P314L	ORF1b	ORF1b	COVID-19	G R S C L	View
91	38125422	D412G	ORF1b	ORF1b	COVID-19	G R S C L	View
92	38125422	A1057T	ORF1b	ORF1b	COVID-19	G R S C L	View
93	38125422	N1595D	ORF1b	ORF1b	COVID-19	G R S C L	View
94	38125422	V2536I	ORF1b	ORF1b	COVID-19	G R S C L	View
95	38125422	R2674E	ORF1b	ORF1b	COVID-19	G R S C L	View
96	40100755	G662S	ORF1b	ORF1b	COVID-19		View
97	40100755	I1566V	ORF1b	ORF1b	COVID-19		View
98	40100755	L829I	ORF1b	ORF1b	COVID-19		View
99	40100755	Y264H	ORF1b	ORF1b	COVID-19		View
100	40100755	Y271H	ORF1b	ORF1b	COVID-19		View
101	36409093	C18877T	ORF1b	ORF1b	COVID-19	R S L	View
102	36409093	P314L	ORF1b	ORF1b	COVID-19	R S L	View
103	36560780	P314L	ORF1b	ORF1b	COVID-19		View
104	36560780	Y1464C	ORF1b	ORF1b	COVID-19		View
105	36560780	P1427L	ORF1b	ORF1b	COVID-19		View
106	36755883	T1050N	ORF1b	ORF1b	COVID-19	G R L	View
107	35759503	A1008P	ORF1b	ORF1b	COVID-19	R L	View
108	35759503	A1525S	ORF1b	ORF1b	COVID-19	R L	View
109	35759503	A17431G	ORF1b	ORF1b	COVID-19	R L	View
110	35759503	A20059G	ORF1b	ORF1b	COVID-19	R L	View
111	35759503	A21137G	ORF1b	ORF1b	COVID-19	R L	View
112	35759503	C14120T	ORF1b	ORF1b	COVID-19	R L	View
113	35759503	C14408T	ORF1b	ORF1b	COVID-19	R L	View
114	35759503	C16349T	ORF1b	ORF1b	COVID-19	R L	View
115	35759503	C16466T	ORF1b	ORF1b	COVID-19	R L	View
116	35759503	C17125T	ORF1b	ORF1b	COVID-19	R L	View
117	35759503	C18176T	ORF1b	ORF1b	COVID-19	R L	View
118	35759503	C19220T	ORF1b	ORF1b	COVID-19	R L	View
119	35759503	C20320T	ORF1b	ORF1b	COVID-19	R L	View
120	35759503	D1668N	ORF1b	ORF1b	COVID-19	R L	View
121	35759503	E2107D	ORF1b	ORF1b	COVID-19	R L	View
122	35759503	F947S	ORF1b	ORF1b	COVID-19	R L	View
123	35759503	G1129C	ORF1b	ORF1b	COVID-19	R L	View
124	35759503	G13726A	ORF1b	ORF1b	COVID-19	R L	View
125	35759503	G15451A	ORF1b	ORF1b	COVID-19	R L	View
126	35759503	G16741T	ORF1b	ORF1b	COVID-19	R L	View
127	35759503	G16852T	ORF1b	ORF1b	COVID-19	R L	View
128	35759503	G18040T	ORF1b	ORF1b	COVID-19	R L	View
129	35759503	G18469A	ORF1b	ORF1b	COVID-19	R L	View
130	35759503	G19788C	ORF1b	ORF1b	COVID-19	R L	View
131	35759503	G20578T	ORF1b	ORF1b	COVID-19	R L	View
132	35759503	G21204T	ORF1b	ORF1b	COVID-19	R L	View
133	35759503	G662S	ORF1b	ORF1b	COVID-19	R L	View
134	35759503	I1322V	ORF1b	ORF1b	COVID-19	R L	View
135	35759503	K2557R	ORF1b	ORF1b	COVID-19	R L	View
136	35759503	K2579N	ORF1b	ORF1b	COVID-19	R L	View
137	35759503	L1220F	ORF1b	ORF1b	COVID-19	R L	View
138	35759503	P1000L	ORF1b	ORF1b	COVID-19	R L	View
139	35759503	P1570L	ORF1b	ORF1b	COVID-19	R L	View
140	35759503	P314L	ORF1b	ORF1b	COVID-19	R L	View
141	35759503	S1985P	ORF1b	ORF1b	COVID-19	R L	View
142	35759503	S2198G	ORF1b	ORF1b	COVID-19	R L	View
143	35759503	S961L	ORF1b	ORF1b	COVID-19	R L	View
144	35759503	T16307C	ORF1b	ORF1b	COVID-19	R L	View
145	35759503	T19420C	ORF1b	ORF1b	COVID-19	R L	View
146	35759503	V1092F	ORF1b	ORF1b	COVID-19	R L	View
147	35759503	V87I	ORF1b	ORF1b	COVID-19	R L	View
148	35759503	Y470N	ORF1b	ORF1b	COVID-19	R L	View
149	37059256	P314L	ORF1b	ORF1b	COVID-19	R S L	View
150	37903828	A1918V	ORF1b	ORF1b	COVID-19	R L	View
151	37903828	E1264D	ORF1b	ORF1b	COVID-19	R L	View
152	37903828	P218L	ORF1b	ORF1b	COVID-19	R L	View
153	37903828	P314L	ORF1b	ORF1b	COVID-19	R L	View
154	37903828	T67I	ORF1b	ORF1b	COVID-19	R	View
155	37903828	K1383R	ORF1b	ORF1b	COVID-19	R L	View
156	38348230	P314L	ORF1b	ORF1b	COVID-19	C L	View
157	38348230	G662S	ORF1b	ORF1b	COVID-19	C L	View
158	38348230	V783I	ORF1b	ORF1b	COVID-19	C L	View
159	38348230	P1000L	ORF1b	ORF1b	COVID-19	C L	View
160	38348230	R1078C	ORF1b	ORF1b	COVID-19	C L	View
161	38348230	R1502K	ORF1b	ORF1b	COVID-19	C L	View
162	38348230	A1868V	ORF1b	ORF1b	COVID-19	C L	View
163	38348230	A1918V	ORF1b	ORF1b	COVID-19	C L	View
164	38348230	V2287I	ORF1b	ORF1b	COVID-19	C L	View
165	37260697	P323L	ORF1b	ORF1b	COVID-19	R S C L	View
166	40006937	G15451A	ORF1b	ORF1b	COVID-19	S L	View
167	33570490	P314L	ORF1b	ORF1b	COVID-19		View
168	33580783	C14408T	ORF1b	ORF1b	COVID-19	R	View
169	35208920	P314L	ORF1b	ORF1b	COVID-19	R L	View
170	33468702	A1844V	ORF1b	ORF1b	COVID-19	R S L	View
171	38684722	T13924G	ORF1b	ORF1b	COVID-19	S C L	View
172	38684722	A13928T	ORF1b	ORF1b	COVID-19	S C L	View
173	38684722	A14359C	ORF1b	ORF1b	COVID-19	S C L	View
174	38684722	G14831A	ORF1b	ORF1b	COVID-19	S C L	View
175	38684722	G14831T	ORF1b	ORF1b	COVID-19	S C L	View
176	38684722	T14996C	ORF1b	ORF1b	COVID-19	S C L	View
177	38684722	G15451A	ORF1b	ORF1b	COVID-19	S C L	View
178	38684722	T15682A	ORF1b	ORF1b	COVID-19	S C L	View
179	38684722	T15685A	ORF1b	ORF1b	COVID-19	S C L	View
180	38684722	G15769T	ORF1b	ORF1b	COVID-19	S C L	View
181	38684722	G15814A	ORF1b	ORF1b	COVID-19	D S C L	View
182	38684722	G15822A	ORF1b	ORF1b	COVID-19	S C L	View
183	38684722	G15822T	ORF1b	ORF1b	COVID-19	D S C L	View
184	38684722	T15835C	ORF1b	ORF1b	COVID-19	S C L	View
185	38684722	G15836T	ORF1b	ORF1b	COVID-19	D S C L	View
186	38684722	T15877C	ORF1b	ORF1b	COVID-19	S C L	View
187	38684722	W153G	ORF1b	ORF1b	COVID-19	S C L	View
188	38684722	Y154F	ORF1b	ORF1b	COVID-19	S C L	View
189	38684722	I298L	ORF1b	ORF1b	COVID-19	S C L	View
190	38684722	C455Y	ORF1b	ORF1b	COVID-19	S C L	View
191	38684722	C455F	ORF1b	ORF1b	COVID-19	S C L	View
192	38684722	M510T	ORF1b	ORF1b	COVID-19	S C L	View
193	38684722	G662S	ORF1b	ORF1b	COVID-19	S C L	View
194	38684722	Y739N	ORF1b	ORF1b	COVID-19	S C L	View
195	38684722	L740M	ORF1b	ORF1b	COVID-19	S C L	View
196	38684722	A768S	ORF1b	ORF1b	COVID-19	S C L	View
197	38684722	V783I	ORF1b	ORF1b	COVID-19	S C L	View
198	38684722	M785I	ORF1b	ORF1b	COVID-19	S C L	View
199	38684722	C790R	ORF1b	ORF1b	COVID-19	S C L	View
200	38684722	C790F	ORF1b	ORF1b	COVID-19	S C L	View
201	38684722	C804R	ORF1b	ORF1b	COVID-19	S C L	View
202	36547242	P314L	ORF1b	ORF1b	COVID-19	S C L	View
203	36547242	I1411T	ORF1b	ORF1b	COVID-19	S C L	View
204	36547242	P1664S	ORF1b	ORF1b	COVID-19	S C L	View
205	36343703	C14408T	ORF1b	ORF1b	COVID-19	R	View
206	36343703	C17747T	ORF1b	ORF1b	COVID-19	R	View
207	36343703	A17858G	ORF1b	ORF1b	COVID-19	R	View
208	36343703	C18060T	ORF1b	ORF1b	COVID-19	R	View
209	36343703	P314L	ORF1b	ORF1b	COVID-19	R	View
210	36343703	P1427L	ORF1b	ORF1b	COVID-19	R	View
211	36343703	Y1464C	ORF1b	ORF1b	COVID-19	R	View
212	36343703	C14805T	ORF1b	ORF1b	COVID-19	R	View
213	36343703	C18877T	ORF1b	ORF1b	COVID-19	R	View
214	36343703	A20268G	ORF1b	ORF1b	COVID-19	R	View
215	32595354	C18877T	ORF1b	ORF1b	COVID-19	R L	View
216	32595354	C17690T	ORF1b	ORF1b	COVID-19	R L	View
217	33662015	C6017T	ORF1b	ORF1b	COVID-19	R L	View
218	33662015	P1427I	ORF1b	ORF1b	COVID-19	R L	View
219	33662015	P1427L	ORF1b	ORF1b	COVID-19	R L	View
220	33662015	Y1464C	ORF1b	ORF1b	COVID-19	R L	View
221	36016239	G14274A	ORF1b	ORF1b	COVID-19	R L	View
222	36016239	C14408T	ORF1b	ORF1b	COVID-19	R L	View
223	36016239	C15656T	ORF1b	ORF1b	COVID-19	R L	View
224	36016239	P314L	ORF1b	ORF1b	COVID-19	R L	View
225	36016239	T730I	ORF1b	ORF1b	COVID-19	R L	View
226	33991487	D1183Y	ORF1b	ORF1b	Cell line	G S	View
227	33991487	P976L	ORF1b	ORF1b	Cell line	G S	View
228	36870749	P314L	ORF1b	ORF1b	Cell line	G L	View