All Curated Mutation Sites in HEV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HEV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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ORF1
  
ORF2
  
ORF3
  
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Keyword: ORF3
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 19393700 C5145T
ORF3
ORF3
HEV Infection
G
R
L
View
2 33877740 A88N
ORF3
ORF3
HEV Infection
G
R
C
L
View
3 33877740 A88V
ORF3
ORF3
HEV Infection
G
R
C
L
View
4 33877740 D90G
ORF3
ORF3
HEV Infection
G
R
C
L
View
5 33877740 H81C
ORF3
ORF3
HEV Infection
G
R
I
C
L
View
6 33877740 L87P
ORF3
ORF3
HEV Infection
G
R
C
L
View
7 33877740 N82I
ORF3
ORF3
HEV Infection
G
R
C
L
View
8 33877740 P77L
ORF3
ORF3
HEV Infection
G
R
C
L
View
9 33877740 R92Q
ORF3
ORF3
HEV Infection
G
R
C
L
View
10 33877740 S79L
ORF3
ORF3
HEV Infection
G
R
I
C
L
View
11 33877740 Y80T
ORF3
ORF3
HEV Infection
G
R
C
L
View
12 31753030 A31T
ORF3
ORF3
Hepatitis-Splenomegaly Syndrome
R
L
View
13 31753030 G46D
ORF3
ORF3
Hepatitis-Splenomegaly Syndrome
R
L
View
14 31753030 Q35H
ORF3
ORF3
Hepatitis-Splenomegaly Syndrome
R
L
View
15 31753030 S15T
ORF3
ORF3
Hepatitis-Splenomegaly Syndrome
R
L
View
16 39793027 C18A
ORF3
ORF3
Cell line
G
T
View
17 39793027 C18S
ORF3
ORF3
Cell line
G
T
View
18 39793027 C21A
ORF3
ORF3
Cell line
G
T
View
19 39793027 C21S
ORF3
ORF3
Cell line
G
T
View
20 23054435 57delQ
ORF3
ORF3
Acute Viral Hepatitis
Liver Failure, Acute
G
R
S
C
L
View
21 23054435 S58P
ORF3
ORF3
Acute Viral Hepatitis
Liver Failure, Acute
G
R
S
C
L
View
Contents
Description

The table shows all curated mutation sites of HEV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.