All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: ORF3

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	35966679	S26L	ORF3	ORF3a	COVID-19	G L	View
2	37224159	T2911C	NSP3;ORF3	ORF1a;ORF3a	COVID-19	G R L	View
3	36755883	P240S	ORF3	ORF3a	COVID-19	G R L	View
4	35992703	S272G	ORF3	ORF3a	COVID-19	G L	View
5	35992703	D22Y	ORF3	ORF3a	COVID-19	G L	View
6	35992703	W128L	ORF3	ORF3a	COVID-19	G L	View
7	35992703	D155Y	ORF3	ORF3a	COVID-19	G L	View
8	35992703	L140F	ORF3	ORF3a	COVID-19	G L	View
9	33127745	G251V	ORF3	ORF3a	COVID-19	G R L	View
10	38435775	K16T	ORF3	ORF3a	COVID-19	C L	View
11	38435775	S26L	ORF3	ORF3a	COVID-19	C L	View
12	38435775	G100C	ORF3	ORF3a	COVID-19	C L	View
13	38435775	W131L	ORF3	ORF3a	COVID-19	C L	View
14	38435775	W131C	ORF3	ORF3a	COVID-19	C L	View
15	40063870	N144S	ORF1ab;ORF3a	ORF1ab;ORF3a	COVID-19	R L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.