All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: ORF7a

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	39584063	C27874T	ORF7a	ORF7a		R	View
2	35233783	P45L	ORF7a	ORF7a		G R L	View
3	35233783	T1055A	ORF7a	ORF7a		G R L	View
4	35658876	T120I	ORF7a	ORF7a		G S L	View
5	35658876	V82A	ORF7a	ORF7a		G S L	View
6	38397027	H47Y	ORF7a	ORF7a		G R S T	View
7	35551247	I110V	ORF7a	ORF7a		G L	View
8	35658876	L56X	ORF7a	ORF7a		S L	View
9	35658876	Q94X	ORF7a	ORF7a		S L	View
10	35658876	Q95X	ORF7a	ORF7a		S L	View
11	35764775	G38V	ORF7a	ORF7a		L	View
12	35764775	T120I	ORF7a	ORF7a		L	View
13	35764775	V82A	ORF7a	ORF7a		L	View
14	38397027	H47N	ORF7a	ORF7a			View
15	37965255	F63H	ORF7a	ORF7a	COVID-19	G R C L	View
16	37965255	H47Y	ORF7a	ORF7a	COVID-19	G R C L	View
17	37275159	C15C	ORF7a	ORF7a	COVID-19	G R S C L	View
18	37275159	T45C	ORF7a	ORF7a	COVID-19	G R S C L	View
19	39604601	L116F	ORF7a	ORF7a	COVID-19	G L	View
20	35966675	T120I	ORF7a	ORF7a	COVID-19	G R S C L	View
21	35966675	V82A	ORF7a	ORF7a	COVID-19	G R S C L	View
22	35966679	V82A	ORF7a	ORF7a	COVID-19	G L	View
23	35966679	T120I	ORF7a	ORF7a	COVID-19	G L	View
24	36298851	C27527T	ORF7a	ORF7a	COVID-19	G R	View
25	36298851	P45L	ORF7a	ORF7a	COVID-19	G R	View
26	36687433	V82A	ORF7a	ORF7a	COVID-19	G R S L	View
27	36687433	T120I	ORF7a	ORF7a	COVID-19	G R S L	View
28	35759503	P45L	ORF7a	ORF7a	COVID-19	G R L	View
29	37993530	C359T	ORF7a	ORF7a	COVID-19	G R S L	View
30	37993530	T245C	ORF7a	ORF7a	COVID-19	G R S L	View
31	38605705	C27532T	ORF7a	ORF7a	COVID-19	G R S C L	View
32	38605705	H47Y	ORF7a	ORF7a	COVID-19	G R S C L	View
33	37744926	C27532T	ORF7a	ORF7a	COVID-19	G R S C L	View
34	37744926	H47Y	ORF7a	ORF7a	COVID-19	G R S C L	View
35	37224159	C27527T	ORF7a	ORF7a	COVID-19	G R L	View
36	37224159	P45L	ORF7a	ORF7a	COVID-19	G R L	View
37	37270625	T24I	ORF7a	ORF7a	COVID-19	G R S C L	View
38	37270625	T39I	ORF7a	ORF7a	COVID-19	G R S C L	View
39	37376693	C20719T	ORF7a	ORF7a	COVID-19	G R S L	View
40	37376693	C27494T	ORF7a	ORF7a	COVID-19	G R S L	View
41	37376693	P34L	ORF7a	ORF7a	COVID-19	G R S L	View
42	34634791	V82A	ORF7a	ORF7a	COVID-19	G R S	View
43	34634791	N43Y	ORF7a	ORF7a	COVID-19	G R S	View
44	34634791	L116F	ORF7a	ORF7a	COVID-19	G R S	View
45	34634791	P34S	ORF7a	ORF7a	COVID-19	G R S	View
46	34634791	A105S	ORF7a	ORF7a	COVID-19	G R S	View
47	38791536	R78C	ORF7a	ORF7a	COVID-19	G R L	View
48	37124420	T115I	ORF7a	ORF7a	COVID-19	G S I C L	View
49	34634791	E92K	ORF7a	ORF7a	COVID-19	G R S	View
50	35992703	H73Y	ORF7a	ORF7a	COVID-19	G L	View
51	35992703	P34S	ORF7a	ORF7a	COVID-19	G L	View
52	35371558	P45L	ORF7a	ORF7a	COVID-19	G L	View
53	38601946	C27509T	ORF7a	ORF7a	COVID-19	G R C L	View
54	38601946	T39I	ORF7a	ORF7a	COVID-19	G R C L	View
55	39339912	A105V	ORF7a	ORF7a	COVID-19	G R	View
56	38605705	C27513T	ORF7a	ORF7a	COVID-19	G R S C L	View
57	40143342	E92K	ORF7a	ORF7a	COVID-19	R S L	View
58	40143342	L116F	ORF7a	ORF7a	COVID-19	R S L	View
59	40143342	P45L	ORF7a	ORF7a	COVID-19	R S L	View
60	40143342	T120I	ORF7a	ORF7a	COVID-19	R S L	View
61	40143342	V82A	ORF7a	ORF7a	COVID-19	R S L	View
62	34245452	T27484C	ORF7a	ORF7a	COVID-19	R	View
63	34245452	V1176F	ORF7a	ORF7a	COVID-19	R	View
64	36090111	R78L	ORF7a	ORF7a	COVID-19	R C L	View
65	36090111	T120I	ORF7a	ORF7a	COVID-19	R C L	View
66	36090111	V82A	ORF7a	ORF7a	COVID-19	R C L	View
67	36841805	T120I	ORF7a	ORF7a	COVID-19	R	View
68	35759503	C27527T	ORF7a	ORF7a	COVID-19	R L	View
69	35759503	C27739T	ORF7a	ORF7a	COVID-19	R L	View
70	35759503	C27752T	ORF7a	ORF7a	COVID-19	R L	View
71	35759503	G27478T	ORF7a	ORF7a	COVID-19	R L	View
72	35759503	L116F	ORF7a	ORF7a	COVID-19	R L	View
73	35759503	T120I	ORF7a	ORF7a	COVID-19	R L	View
74	35759503	T27638C	ORF7a	ORF7a	COVID-19	R L	View
75	35759503	V29L	ORF7a	ORF7a	COVID-19	R L	View
76	35759503	V82A	ORF7a	ORF7a	COVID-19	R L	View
77	37903828	N38T	ORF7a	ORF7a	COVID-19	R L	View
78	37903828	S5L	ORF7a	ORF7a	COVID-19	R L	View
79	37903828	A15S	ORF7a	ORF7a	COVID-19	R L	View
80	37903828	D36Y	ORF7a	ORF7a	COVID-19	R L	View
81	37903828	T120I	ORF7a	ORF7a	COVID-19	R L	View
82	37903828	V82A	ORF7a	ORF7a	COVID-19	R L	View
83	37903828	A43S	ORF7a	ORF7a	COVID-19	R L	View
84	38348230	V82A	ORF7a	ORF7a	COVID-19	C L	View
85	38348230	T120I	ORF7a	ORF7a	COVID-19	C L	View
86	36057416	Q94X	ORF7a	ORF7a	COVID-19	R L	View
87	32300673	C27493T	ORF7a	ORF7a	COVID-19	R	View
88	32300673	P34S	ORF7a	ORF7a	COVID-19	R	View
89	34305826	A105V	ORF7a	ORF7a	COVID-19	R L	View
90	34578363	L116F	ORF7a	ORF7a	COVID-19	R L	View
91	34943191	A105V	ORF7a	ORF7a	COVID-19	C L	View
92	38435775	T39I	ORF7a	ORF7a	COVID-19	C L	View
93	38435775	S83L	ORF7a	ORF7a	COVID-19	C L	View
94	38435775	V82A	ORF7a	ORF7a	COVID-19	C L	View
95	38435775	T120I	ORF7a	ORF7a	COVID-19	C L	View
96	38435775	K79-R79del	ORF7a	ORF7a	COVID-19	C L	View
97	36786950	F101Y	ORF7a	ORF7a	COVID-19	R S C L	View
98	36547242	V71I	ORF7a	ORF7a	COVID-19	S C L	View
99	36547242	V82A	ORF7a	ORF7a	COVID-19	S C L	View
100	36547242	V93F	ORF7a	ORF7a	COVID-19	S C L	View
101	36547242	T120I	ORF7a	ORF7a	COVID-19	S C L	View
102	38632523	A27458G	ORF7a	ORF7a	COVID-19	G R L	View
103	38632523	E22G	ORF7a	ORF7a	COVID-19	G R L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.