All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: RBM

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	34337269	S477N	RBM	S		G	View
2	35680610	N501Y	RBM	S		G	View
3	35680610	Q493R	RBM	S		G	View
4	35680610	T478K	RBM	S		G	View
5	35777362	E484A	RBM	S		G R S	View
6	35777362	G446S	RBM	S		G R S	View
7	35777362	G496S	RBM	S		G R S	View
8	35777362	K417N	RBM	S		G R S	View
9	35777362	N501Y	RBM	S		G R S	View
10	35777362	Q493R	RBM	S		G R S	View
11	35777362	Q498R	RBM	S		G R S	View
12	35777362	S477N	RBM	S		G R S	View
13	35777362	T478K	RBM	S		G R S	View
14	35777362	Y505H	RBM	S		G R S	View
15	37775095	T452R	RBM	S		G	View
16	37775095	L452K	RBM	S		G I	View
17	37548589	S477N	RBM	S		G	View
18	37548589	T478K	RBM	S		G	View
19	37548589	E484A	RBM	S		G T	View
20	35943779	Q498R	RBM	S		G S	View
21	35723403	K417T	RBM	S		L	View
22	35943779	G446S	RBM	S		S	View
23	35169135	T478K	RBM	S	COVID-19	G	View
24	40362305	E484K	RBM	S	COVID-19		View
25	40362305	N501Y	RBM	S	COVID-19		View
26	33384909	F486L	RBM	S	COVID-19	R	View
27	33384909	L452M	RBM	S	COVID-19	R	View
28	33384909	N501T	RBM	S	COVID-19	R	View
29	33758785	N439K	RBM	S	COVID-19	R L	View
30	34400835	Q498R	RBM	S	COVID-19		View
31	34400835	E484K	RBM	S	COVID-19		View
32	34400835	N501Y	RBM	S	COVID-19		View
33	34400835	S477N	RBM	S	COVID-19		View
34	36590900	L452R	RBM	S	Cell line	G	View
35	36590900	T478K	RBM	S	Cell line	G	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.