All Curated Mutation Sites in HEV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HEV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

Click the button below to quickly view the viral genes/regions/protein for mutation

Keyword: RdRp

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	27320795	C1483W	RdRp	ORF1	Liver Failure, Acute Acute Viral Hepatitis	G R S C L	View
2	27320795	N1530T	RdRp	ORF1	Liver Failure, Acute Acute Viral Hepatitis	G R S C L	View
3	27222534	D1384G	RdRp	ORF1	Liver Cirrhosis Liver Failure	D G R C L	View
4	27222534	G1634R	RdRp	ORF1	Liver Cirrhosis Liver Failure	D G R C L	View
5	27222534	K1383N	RdRp	ORF1	Liver Cirrhosis Liver Failure	D G R C L	View
6	27222534	V1479I	RdRp	ORF1	Liver Cirrhosis Liver Failure	D G R C L	View
7	27222534	Y1587F	RdRp	ORF1	Liver Cirrhosis Liver Failure	D G R C L	View
8	37984761	G1634R	RdRp	ORF1	HEV Infection Cell line	D G R	View
9	37984761	Y1320H	RdRp	ORF1	HEV Infection Cell line	D G R	View
10	38242291	F204L	RdRp	ORF1	HEV Infection	G R S L	View
11	38242291	L238F	RdRp	ORF1	HEV Infection	G R S L	View
12	36942308	D1384G	RdRp	ORF1	HEV Infection	D G C	View
13	36942308	G1634R	RdRp	ORF1	HEV Infection	D G C	View
14	36942308	K1383N	RdRp	ORF1	HEV Infection	D G C	View
15	36942308	V1305I	RdRp	ORF1	HEV Infection	G C	View
16	36809085	K1634G	RdRp	ORF1	HEV Infection	G R S	View
17	36809085	K1634R	RdRp	ORF1	HEV Infection	G R S	View
18	36809085	G1634R	RdRp	ORF1	HEV Infection	D G R S	View
19	36809085	K1383N	RdRp	ORF1	HEV Infection	D G R S	View
20	36809085	Y1320H	RdRp	ORF1	HEV Infection	D G R S	View
21	27174035	G1634R	RdRp	ORF1	Chronic Hepatitis E	D G	View
22	27174035	K1383N	RdRp	ORF1	Chronic Hepatitis E	D G	View
23	27174035	Y1320H	RdRp	ORF1	Chronic Hepatitis E	D G	View
24	37363232	D1384G	RdRp	ORF1	Chronic Hepatitis E	D R S L	View
25	37363232	G1634K	RdRp	ORF1	Chronic Hepatitis E	D R S L	View
26	37363232	K1383N	RdRp	ORF1	Chronic Hepatitis E	D R S L	View
27	37363232	K1398R	RdRp	ORF1	Chronic Hepatitis E	D R S L	View
28	37363232	V1479I	RdRp	ORF1	Chronic Hepatitis E	D R S L	View
29	38434938	A1343V	RdRp	ORF1	Chronic Hepatitis E	D G	View
30	27485920	A5054G	RdRp	ORF1	Cell line	G R	View
31	27485920	C4435T	RdRp	ORF1	Cell line	G R	View
32	29422085	A1213V	RdRp	ORF1	Cell line	G	View
33	29422085	Q1246H	RdRp	ORF1	Cell line	G	View
34	31896581	G1634R	RdRp	ORF1	Cell line	D G R S I	View
35	26784284	V1480I	RdRp	ORF1	Acute Viral Hepatitis	G R S C L	View
36	26784284	V1693M	RdRp	ORF1	Acute Viral Hepatitis	G R S C L	View

Contents
Description

The table shows all curated mutation sites of HEV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.