All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: X Promoter

ID	PMID	Mutation	Gene/Protein/Region	Disease	Description	Detail
1	17888035	G1317A	X Promoter	Hepatitis B, Chronic Carcinoma, Hepatocellular	G R L	View
2	17888035	T1341G	X Promoter	Hepatitis B, Chronic Carcinoma, Hepatocellular	G R L	View
3	17888035	T1341A	X Promoter	Hepatitis B, Chronic Carcinoma, Hepatocellular	G R L	View
4	17888035	T1341C	X Promoter	Hepatitis B, Chronic Carcinoma, Hepatocellular	G R L	View
5	20550526	G1053A	X Promoter	Liver Cirrhosis	C	View
6	20550526	G1229A	X Promoter	Liver Cirrhosis	C	View
7	31601912	A1314G	X Promoter	Occult HBV Infection	G R C L	View
8	31601912	A1320G	X Promoter	Occult HBV Infection	G R C L	View
9	31601912	A1329A	X Promoter	Occult HBV Infection	G R C L	View
10	31601912	T1335C	X Promoter	Occult HBV Infection	G R C L	View
11	31601912	T1350C	X Promoter	Occult HBV Infection	G R C L	View
12	31601912	T1353G	X Promoter	Occult HBV Infection	G R C L	View
13	17825452	A1565A	X Promoter	Hepatitis B, Chronic	G R	View
14	17825452	A1565G	X Promoter	Hepatitis B, Chronic	G R	View
15	17825452	T1494C	X Promoter	Hepatitis B, Chronic	G R	View
16	17825452	T1494T	X Promoter	Hepatitis B, Chronic	G R	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.