All Curated Mutation Sites in HIV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HIV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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Keyword: gp120
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 33883222 F174L
gp120
Env
Acquired Immunodeficiency Syndrome
G
C
View
2 33883222 G150R
gp120
Env
Acquired Immunodeficiency Syndrome
G
C
View
3 33883222 G310R
gp120
Env
Acquired Immunodeficiency Syndrome
D
G
C
View
4 33883222 I307V
gp120
Env
Acquired Immunodeficiency Syndrome
G
C
View
5 33883222 L124F
gp120
Env
Acquired Immunodeficiency Syndrome
G
C
View
6 33883222 N132K
gp120
Env
Acquired Immunodeficiency Syndrome
G
C
View
7 33883222 S304G
gp120
Env
Acquired Immunodeficiency Syndrome
G
C
View
8 31126879 A281T
gp120
Env
HIV Infections
G
R
S
C
L
T
View
9 31126879 D368K
gp120
Env
HIV Infections
G
R
S
C
L
T
View
10 31126879 D368R
gp120
Env
HIV Infections
G
R
S
C
L
T
View
11 31126879 N160K
gp120
Env
HIV Infections
G
R
S
C
L
T
View
12 31126879 N262S
gp120
Env
HIV Infections
G
R
S
I
C
L
View
13 31126879 N262W
gp120
Env
HIV Infections
G
R
S
I
C
L
View
14 31126879 N280Y
gp120
Env
HIV Infections
G
R
S
C
L
View
15 31126879 N332A
gp120
Env
HIV Infections
G
R
S
C
L
T
View
16 31126879 N332K
gp120
Env
HIV Infections
G
R
S
C
L
T
View
17 31126879 N448K
gp120
Env
HIV Infections
G
R
S
I
C
L
View
18 31126879 N448S
gp120
Env
HIV Infections
G
R
S
I
C
L
View
19 31126879 P214I
gp120
Env
HIV Infections
G
R
S
C
L
View
20 31126879 P214Q
gp120
Env
HIV Infections
G
R
S
C
L
View
21 31126879 Q293E
gp120
Env
HIV Infections
G
R
S
C
L
View
22 31126879 Q293K
gp120
Env
HIV Infections
G
R
S
C
L
View
23 31126879 Q293R
gp120
Env
HIV Infections
G
R
S
C
L
View
24 31126879 R444T
gp120
Env
HIV Infections
G
R
S
C
L
View
25 31126879 S291P
gp120
Env
HIV Infections
G
R
S
C
L
View
26 31126879 S291T
gp120
Env
HIV Infections
G
R
S
C
L
View
27 31126879 V293E
gp120
Env
HIV Infections
G
R
S
C
L
View
28 31126879 V293K
gp120
Env
HIV Infections
G
R
S
C
L
View
29 31126879 V293R
gp120
Env
HIV Infections
G
R
S
C
L
View
30 24758333 I467T
gp120
Env
Cell line
G
R
S
View
31 25174000 E168K
gp120
Env
Cell line
G
I
L
T
View
32 25174000 I154A
gp120
Env
Cell line
G
I
L
T
View
33 25174000 L193A
gp120
Env
Cell line
G
I
L
T
View
34 25174000 M434A
gp120
Env
Cell line
G
I
L
T
View
35 25174000 N156A
gp120
Env
Cell line
G
I
L
T
View
36 25174000 N188A
gp120
Env
Cell line
G
I
L
T
View
37 25174000 N197S
gp120
Env
Cell line
G
I
L
T
View
38 25174000 R440E
gp120
Env
Cell line
G
I
L
T
View
39 25174000 Y435A
gp120
Env
Cell line
G
I
L
T
View
40 25849367 S375W
gp120
Env
Cell line
G
I
T
View
41 29677220 A58V
gp120
Env
Cell line
G
View
42 29677220 A60T
gp120
Env
Cell line
G
View
43 29677220 M426L
gp120
Env
Cell line
G
View
44 29677220 P79L
gp120
Env
Cell line
G
View
45 29677220 Q442P
gp120
Env
Cell line
G
View
46 29677220 S143N
gp120
Env
Cell line
G
View
47 32156815 N625A
gp120;gp41
Env
HIV Infections
D
G
R
C
L
View
48 32160290 204delA
gp120
Env
HIV Infections
D
G
R
L
View
49 32160290 375delS
gp120
Env
HIV Infections
D
G
R
L
View
50 32160290 426delM
gp120
Env
HIV Infections
D
G
R
L
View
51 32160290 434delM
gp120
Env
HIV Infections
D
G
R
L
View
52 32160290 475delM
gp120
Env
HIV Infections
D
G
R
L
View
53 32160290 A204G
gp120
Env
HIV Infections
D
G
R
L
View
54 32160290 A204L
gp120
Env
HIV Infections
D
G
R
L
View
55 32160290 A204P
gp120
Env
HIV Infections
D
G
R
L
View
56 32160290 A204S
gp120
Env
HIV Infections
D
G
R
L
View
57 32160290 A204T
gp120
Env
HIV Infections
D
G
R
L
View
58 32160290 A204V
gp120
Env
HIV Infections
D
G
R
L
View
59 32160290 G167N
gp120
Env
HIV Infections
D
G
R
L
View
60 32160290 I154V
gp120
Env
HIV Infections
D
G
R
L
View
61 32160290 I323T
gp120
Env
HIV Infections
D
G
R
L
View
62 32160290 I371V
gp120
Env
HIV Infections
D
G
R
L
View
63 32160290 K192T
gp120
Env
HIV Infections
D
G
R
L
View
64 32160290 K322A
gp120
Env
HIV Infections
D
G
R
L
View
65 32160290 L116F
gp120
Env
HIV Infections
D
G
R
L
View
66 32160290 L116I
gp120
Env
HIV Infections
D
G
R
L
View
67 32160290 L116Q
gp120
Env
HIV Infections
D
G
R
L
View
68 32160290 L134W
gp120
Env
HIV Infections
D
G
R
L
View
69 32160290 M426K
gp120
Env
HIV Infections
D
G
R
L
View
70 32160290 M426L
gp120
Env
HIV Infections
D
G
R
L
View
71 32160290 M426Q
gp120
Env
HIV Infections
D
G
R
L
View
72 32160290 M426R
gp120
Env
HIV Infections
D
G
R
L
View
73 32160290 M426S
gp120
Env
HIV Infections
D
G
R
L
View
74 32160290 M426T
gp120
Env
HIV Infections
D
G
R
L
View
75 32160290 M426V
gp120
Env
HIV Infections
D
G
R
L
View
76 32160290 M434I
gp120
Env
HIV Infections
D
G
R
L
View
77 32160290 M434T
gp120
Env
HIV Infections
D
G
R
L
View
78 32160290 M434V
gp120
Env
HIV Infections
D
G
R
L
View
79 32160290 M475I
gp120
Env
HIV Infections
D
G
R
L
View
80 32160290 M475K
gp120
Env
HIV Infections
D
G
R
L
View
81 32160290 S195N
gp120
Env
HIV Infections
D
G
R
L
View
82 32160290 S375H
gp120
Env
HIV Infections
D
G
R
L
View
83 32160290 S375I
gp120
Env
HIV Infections
D
G
R
L
View
84 32160290 S375K
gp120
Env
HIV Infections
D
G
R
L
View
85 32160290 S375L
gp120
Env
HIV Infections
D
G
R
L
View
86 32160290 S375M
gp120
Env
HIV Infections
D
G
R
L
View
87 32160290 S375N
gp120
Env
HIV Infections
D
G
R
L
View
88 32160290 S375R
gp120
Env
HIV Infections
D
G
R
L
View
89 32160290 S375T
gp120
Env
HIV Infections
D
G
R
L
View
90 32160290 V506A
gp120
Env
HIV Infections
D
G
R
L
View
91 32160290 V506L
gp120
Env
HIV Infections
D
G
R
L
View
92 32457241 D474N
gp120
Env
HIV Infections
D
G
R
I
L
View
93 32457241 H105Q
gp120
Env
HIV Infections
D
G
R
I
L
View
94 32457241 H375S
gp120
Env
HIV Infections
D
G
R
I
L
View
95 32457241 H375T
gp120
Env
HIV Infections
D
G
R
I
L
View
96 32457241 I108V
gp120
Env
HIV Infections
D
G
R
I
L
View
97 32457241 I475M
gp120
Env
HIV Infections
D
G
R
I
L
View
98 32457241 K476R
gp120
Env
HIV Infections
D
G
R
I
L
View
99 32457241 M475I
gp120
Env
HIV Infections
D
G
R
I
L
View
100 32457241 N474D
gp120
Env
HIV Infections
D
G
R
I
L
View
101 32457241 Q105H
gp120
Env
HIV Infections
D
G
R
I
L
View
102 32457241 Q61Y
gp120
Env
HIV Infections
D
G
R
I
L
View
103 32457241 R476K
gp120
Env
HIV Infections
D
G
R
I
L
View
104 32457241 S375T
gp120
Env
HIV Infections
D
G
R
I
L
View
105 32457241 V108I
gp120
Env
HIV Infections
D
G
R
I
L
View
106 32457241 Y61H
gp120
Env
HIV Infections
D
G
R
I
L
View
107 32464638 M426L
gp120
Env
HIV Infections
D
G
S
L
View
108 32464638 S375N
gp120
Env
HIV Infections
D
G
S
L
View
109 33297399 A316T
gp120
Env
HIV Infections
D
G
R
S
C
L
View
110 33297399 I323V
gp120
Env
HIV Infections
D
G
R
S
C
L
View
111 33466381 N239G
gp120
Env

D
G
View
112 33466381 N425G
gp120
Env

D
G
View
113 33466381 R425G
gp120
Env

D
G
View
114 33832362 M426L
gp120
Env
HIV Infections
D
G
I
View
115 33832362 W427V
gp120
Env
HIV Infections
D
G
I
View
116 39240111 N276N
gp120
Env
HIV Infections
D
G
View
Contents
Description

The table shows all curated mutation sites of HIV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.