All Curated Mutation Sites in HIV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HIV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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Keyword: gp41
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 40358920 V182I
gp41
Env
HIV Infections
D
View
2 18645515 L44M
gp41
Env
HIV Infections
G
T
View
3 18645515 N42T
gp41
Env
HIV Infections
G
T
View
4 18645515 V38A
gp41
Env
HIV Infections
D
G
T
View
5 24616600 E137K
gp41
Env
HIV Infections
G
R
L
View
6 24616600 L45M
gp41
Env
HIV Infections
G
R
L
View
7 24616600 N126K
gp41
Env
HIV Infections
G
R
L
View
8 24616600 N42S
gp41
Env
HIV Infections
G
R
L
View
9 25170621 G123A
gp41
Env
HIV Infections
G
L
View
10 25170621 G36D
gp41
Env
HIV Infections
D
G
L
View
11 25170621 G36V
gp41
Env
HIV Infections
D
G
L
View
12 25170621 L45M
gp41
Env
HIV Infections
D
G
L
View
13 25170621 N43D
gp41
Env
HIV Infections
D
G
L
View
14 25170621 Q40H
gp41
Env
HIV Infections
D
G
L
View
15 25170621 V38A
gp41
Env
HIV Infections
D
G
L
View
16 27992602 D368R
gp41
Env
HIV Infections
G
R
View
17 27992602 L544S
gp41
Env
HIV Infections
D
G
R
View
18 27992602 N637K
gp41
Env
HIV Infections
G
R
View
19 27992602 N656D
gp41
Env
HIV Infections
D
G
R
View
20 27992602 Q552R
gp41
Env
HIV Infections
D
G
R
View
21 27992602 V549A
gp41
Env
HIV Infections
D
G
R
View
22 27992602 V549E
gp41
Env
HIV Infections
D
G
R
View
23 28167814 D121E
gp41
Env
HIV Infections
G
R
S
L
View
24 28167814 E137K
gp41
Env
HIV Infections
D
G
R
S
L
View
25 28167814 H132Y
gp41
Env
HIV Infections
G
R
S
L
View
26 28167814 I69V
gp41
Env
HIV Infections
G
R
S
L
View
27 28167814 N125D
gp41
Env
HIV Infections
G
R
S
L
View
28 28167814 N126K
gp41
Env
HIV Infections
D
G
R
S
L
View
29 28167814 N42S
gp41
Env
HIV Infections
G
R
S
L
View
30 29672607 Q662E
gp41
Env
HIV Infections
G
S
I
C
L
View
31 29672607 R683K
gp41
Env
HIV Infections
G
S
I
C
L
View
32 30040081 I325F
gp41
Env
HIV Infections
D
G
S
C
L
View
33 30040081 L325F
gp41
Env
HIV Infections
D
G
S
C
L
View
34 30040081 T307I
gp41
Env
HIV Infections
D
G
S
C
L
View
35 22333046 N126K
gp41
Env
Cell line
G
T
View
36 22333046 N140I
gp41
Env
Cell line
D
G
I
T
View
37 22333046 N140T
gp41
Env
Cell line
D
G
I
T
View
38 22333046 N42T
gp41
Env
Cell line
G
T
View
39 22333046 V38A
gp41
Env
Cell line
D
G
I
T
View
40 31504041 A612T
gp41
Env
HIV Infections
G
R
View
41 31504041 A667S
gp41
Env
HIV Infections
G
R
View
42 31504041 C604S
gp41
Env
HIV Infections
G
R
View
43 31504041 C605R
gp41
Env
HIV Infections
G
R
View
44 31504041 C605S
gp41
Env
HIV Infections
G
R
View
45 31504041 D624V
gp41
Env
HIV Infections
G
R
View
46 31504041 E560D
gp41
Env
HIV Infections
G
R
View
47 31504041 E584A
gp41
Env
HIV Infections
G
R
View
48 31504041 E632D
gp41
Env
HIV Infections
G
R
View
49 31504041 E634D
gp41
Env
HIV Infections
G
R
View
50 31504041 G459V
gp41
Env
HIV Infections
G
R
View
51 31504041 G572D
gp41
Env
HIV Infections
G
R
View
52 31504041 I603N
gp41
Env
HIV Infections
G
R
View
53 31504041 I635K
gp41
Env
HIV Infections
G
R
View
54 31504041 I635L
gp41
Env
HIV Infections
G
R
View
55 31504041 I635M
gp41
Env
HIV Infections
G
R
View
56 31504041 I635N
gp41
Env
HIV Infections
G
R
View
57 31504041 I635T
gp41
Env
HIV Infections
G
R
View
58 31504041 I635V
gp41
Env
HIV Infections
G
R
View
59 31504041 I642N
gp41
Env
HIV Infections
G
R
View
60 31504041 I682F
gp41
Env
HIV Infections
G
R
View
61 31504041 K500E
gp41
Env
HIV Infections
G
R
View
62 31504041 K508N
gp41
Env
HIV Infections
G
R
View
63 31504041 K683T
gp41
Env
HIV Infections
G
R
View
64 31504041 L545H
gp41
Env
HIV Infections
G
R
View
65 31504041 L555M
gp41
Env
HIV Infections
G
R
View
66 31504041 L566M
gp41
Env
HIV Infections
G
R
View
67 31504041 L566Q
gp41
Env
HIV Infections
G
R
View
68 31504041 L568P
gp41
Env
HIV Infections
G
R
View
69 31504041 L568Q
gp41
Env
HIV Infections
G
R
View
70 31504041 L646S
gp41
Env
HIV Infections
G
R
View
71 31504041 L669S
gp41
Env
HIV Infections
G
R
View
72 31504041 M626K
gp41
Env
HIV Infections
G
R
View
73 31504041 N637T
gp41
Env
HIV Infections
G
R
View
74 31504041 N640D
gp41
Env
HIV Infections
G
R
View
75 31504041 N651H
gp41
Env
HIV Infections
G
R
View
76 31504041 N651Y
gp41
Env
HIV Infections
G
R
View
77 31504041 N656K
gp41
Env
HIV Infections
G
R
View
78 31504041 P498H
gp41
Env
HIV Infections
G
R
View
79 31504041 Q543L
gp41
Env
HIV Infections
G
R
View
80 31504041 Q552L
gp41
Env
HIV Infections
G
R
View
81 31504041 Q575K
gp41
Env
HIV Infections
G
R
View
82 31504041 Q577H
gp41
Env
HIV Infections
G
R
View
83 31504041 Q590H
gp41
Env
HIV Infections
G
R
View
84 31504041 Q619R
gp41
Env
HIV Infections
G
R
View
85 31504041 Q648R
gp41
Env
HIV Infections
G
R
View
86 31504041 Q650H
gp41
Env
HIV Infections
G
R
View
87 31504041 Q653H
gp41
Env
HIV Infections
G
R
View
88 31504041 Q658H
gp41
Env
HIV Infections
G
R
View
89 31504041 S534A
gp41
Env
HIV Infections
G
R
View
90 31504041 S546P
gp41
Env
HIV Infections
G
R
View
91 31504041 S599Y
gp41
Env
HIV Infections
G
R
View
92 31504041 S615T
gp41
Env
HIV Infections
G
R
View
93 31504041 V580D
gp41
Env
HIV Infections
G
R
View
94 31504041 W571R
gp41
Env
HIV Infections
G
R
View
95 31504041 W610R
gp41
Env
HIV Infections
G
R
View
96 31504041 W614R
gp41
Env
HIV Infections
G
R
View
97 31504041 W623R
gp41
Env
HIV Infections
G
R
View
98 31504041 W628R
gp41
Env
HIV Infections
G
R
View
99 31504041 W631K
gp41
Env
HIV Infections
G
R
View
100 31504041 W631R
gp41
Env
HIV Infections
G
R
View
101 31504041 W666R
gp41
Env
HIV Infections
G
R
I
View
102 31504041 W670R
gp41
Env
HIV Infections
G
R
View
103 31504041 W680R
gp41
Env
HIV Infections
G
R
View
104 31504041 Y638H
gp41
Env
HIV Infections
G
R
View
105 31504041 Y638N
gp41
Env
HIV Infections
G
R
View
106 31504041 Y643H
gp41
Env
HIV Infections
G
R
View
107 24884783 I559P
gp41
Env
Cell line
G
S
View
108 25144636 N42T
gp41
Env
Cell line
D
G
R
View
109 25144636 V38A
gp41
Env
Cell line
D
G
R
View
110 25849367 A501C
gp41
Env
Cell line
G
I
T
View
111 25849367 I559P
gp41
Env
Cell line
G
I
T
View
112 25849367 T605C
gp41
Env
Cell line
G
I
T
View
113 29677220 H643Y
gp41
Env
Cell line
G
View
114 29677220 K655M
gp41
Env
Cell line
G
View
115 29677220 M687I
gp41
Env
Cell line
G
View
116 31796053 E560D
gp41
Env
HIV Infections
G
R
View
117 31796053 E560G
gp41
Env
HIV Infections
G
R
View
118 31796053 E560K
gp41
Env
HIV Infections
G
R
View
119 31796053 G546D
gp41
Env
HIV Infections
G
R
View
120 31796053 G547D
gp41
Env
HIV Infections
G
R
View
121 29677220 T626M
gp41
Env
Cell line
G
View
122 31796053 L544S
gp41
Env
HIV Infections
G
R
View
123 29677220 V822I
gp41
Env
Cell line
G
View
124 30566493 M475I
gp41
Env
Cell line
G
S
View
125 30696772 A517V
gp41
Env
Cell line
D
G
R
View
126 30696772 E647G
gp41
Env
Cell line
D
G
R
View
127 30696772 E662G
gp41
Env
Cell line
D
G
R
View
128 30696772 H643Q
gp41
Env
Cell line
D
G
R
View
129 30696772 I515F
gp41
Env
Cell line
D
G
R
View
130 30696772 I515T
gp41
Env
Cell line
D
G
R
View
131 30696772 K588E
gp41
Env
Cell line
D
G
R
View
132 30696772 K588N
gp41
Env
Cell line
D
G
R
View
133 30696772 K601E
gp41
Env
Cell line
D
G
R
View
134 30696772 K665Q
gp41
Env
Cell line
D
G
R
View
135 30696772 L523F
gp41
Env
Cell line
D
G
R
View
136 30696772 L544S
gp41
Env
Cell line
D
G
R
View
137 30696772 N611D
gp41
Env
Cell line
D
G
R
View
138 30696772 N624D
gp41
Env
Cell line
D
G
R
View
139 30696772 N636S
gp41
Env
Cell line
D
G
R
View
140 30696772 N637K
gp41
Env
Cell line
D
G
R
View
141 30696772 Q577R
gp41
Env
Cell line
D
G
R
View
142 30696772 Q590E
gp41
Env
Cell line
D
G
R
View
143 30696772 T605N
gp41
Env
Cell line
D
G
R
View
144 32156815 N625A
gp120;gp41
Env
HIV Infections
D
G
R
C
L
View
145 32197300 N126K
gp41
Env
HIV Infections
D
G
View
146 32392227 Q563A
gp41
Env
HIV Infections
D
G
S
L
View
147 32392227 Q563R
gp41
Env
HIV Infections
D
G
S
L
View
148 32392227 R563A
gp41
Env
HIV Infections
D
G
S
L
View
149 32392227 R563Q
gp41
Env
HIV Infections
D
G
S
L
View
150 33166562 E137K
gp41
Env
HIV Infections
D
G
R
S
L
View
151 16054592 E630Q
gp41
Env
HIV Infections
G
View
152 16054592 L565M
gp41
Env
HIV Infections
G
View
153 16054592 N651I
gp41
Env
HIV Infections
G
View
154 16054592 S641G
gp41
Env
HIV Infections
G
View
Contents
Description

The table shows all curated mutation sites of HIV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.