HPV Target gene Detail Information

> ARHGEF6 Gene Search Result


Gene Information
Gene Name ARHGEF6
Gene ID 9459
Gene Full Name Rac/Cdc42 guanine nucleotide exchange factor 6
Gene Alias COOL2|Cool-2|MRX46|PIXA|alpha-PIX|alphaPIX
Transcripts ENSG00000129675
Virus HPV
Gene Type protein-coding
HPA Location Info Plasma membrane, Cytosol;
Membrane Info Cancer-related genes, Predicted intracellular proteins
Uniport_ID Q15052
HGNC ID HGNC:685
OMIM ID 300267
Summary Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008]
Target gene [ARHGEF6] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5006597 chrX 4 26 0 30 View
5006941 chrX 1 2 0 3 View

Target gene [ARHGEF6] related to Omics data
Data ID Experiment type Sample number Platform
GSE226620 scRNA-seq 30 HiSeq X Ten (Homo sapiens)
GSE139324 scRNA-seq 63 Illumina NextSeq 500 (Homo sapiens)
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE164690 scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
M
  TCGA_CESC 		DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE197461 scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE143026 - ARHGEF6 peak across samples

Peak Plot