HPV Target gene Detail Information

> GLI2 Gene Search Result


Gene Information
Gene Name GLI2
Gene ID 2736
Gene Full Name GLI family zinc finger 2
Gene Alias CJS|HPE9|PHS2|THP1|THP2
Transcripts ENSG00000074047
Virus HPV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Nucleoli;Centrosome, Basal body;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID P10070
HGNC ID HGNC:4318
OMIM ID 165230
Summary This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
Target gene [GLI2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000080 chr2 3237 3564 1220 8021 View
5000761 chr2 87 1 0 88 View
5000791 chr2 83 1 0 84 View
5000888 chr2 68 4 0 72 View
5000918 chr2 62 6 0 68 View
5000947 chr2 57 8 0 65 View
5000948 chr2 57 8 0 65 View
5000972 chr2 53 10 0 63 View
5003305 chr2 4 0 0 4 View
5003488 chr2 3 0 0 3 View
5003572 chr2 3 0 0 3 View
5003573 chr2 3 0 0 3 View
5003852 chr2 2 0 0 2 View
5003853 chr2 2 0 0 2 View
5010086 chr2 157 32 22 211 View
5010087 chr2 2 0 0 2 View
5010088 chr2 53 10 0 63 View
5015516 chr2 547 76 51 674 View
5015517 chr2 2 0 0 2 View
5015518 chr2 99 20 0 119 View

Target gene [GLI2] related to Omics data
Data ID Experiment type Sample number Platform
GSE40774 Expression array 134 Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE143026 - GLI2 peak across samples

Peak Plot