HPV Target gene Detail Information

> HPSE2 Gene Search Result


Gene Information
Gene Name HPSE2
Gene ID 60495
Gene Full Name heparanase 2 (inactive)
Gene Alias HPA2|HPR2|UFS|UFS1
Transcripts ENSG00000172987
Virus HPV
Gene Type protein-coding
HPA Location Info Secreted to extracellular matrix;
Membrane Info Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID Q8WWQ2
HGNC ID HGNC:18374
OMIM ID 613469
Summary This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Target gene [HPSE2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5002242 chr10 11 2 0 13 View
5011719 chr10 15 286 30 331 View
5011720 chr10 31 43 198 272 View

Target gene [HPSE2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048 		Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
E
  GSE140662 		Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
M
  TCGA_CESC 		DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE197461 scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE140662 - HPSE2 expression across samples

Volcano Plot

Bar Plot