HPV Target gene Detail Information

> MCPH1 Gene Search Result


Gene Information
Gene Name MCPH1
Gene ID 79648
Gene Full Name microcephalin 1
Gene Alias BRIT1|MCT
Transcripts ENSG00000147316
Virus HPV
Gene Type protein-coding
HPA Location Info
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q8NEM0
HGNC ID HGNC:6954
OMIM ID 607117
Summary This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
Target gene [MCPH1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5010300 chr8 72 42 16 130 View
5017772 chr8 12 6 0 18 View
5017773 chr8 19 4 0 23 View
5017774 chr8 5 1 0 6 View
5017775 chr8 7 2 3 12 View
5017776 chr8 7 2 3 12 View
5017777 chr8 5 1 1 7 View
5017778 chr8 28 1 2 31 View
5017779 chr8 28 1 2 31 View

Target gene [MCPH1] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048 		Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE40774 Expression array 134 Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE183048 - MCPH1 peak across samples

Peak Plot

> Dataset: GSE143026 - MCPH1 peak across samples

Peak Plot