HPV Target gene Detail Information

> NCK2 Gene Search Result


Gene Information
Gene Name NCK2
Gene ID 8440
Gene Full Name NCK adaptor protein 2
Gene Alias GRB4|NCKbeta
Transcripts ENSG00000071051
Virus HPV
Gene Type protein-coding
HPA Location Info
Membrane Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O43639
HGNC ID HGNC:7665
OMIM ID 604930
Summary This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Target gene [NCK2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5011203 chr2 8 7 0 15 View
5011204 chr2 21 26 0 47 View
5017305 chr2 51 9 15 75 View
5017306 chr2 12 6 0 18 View
5017307 chr2 6 3 2 11 View
5017308 chr2 141 7 4 152 View
5017309 chr2 115 7 1 123 View
5017310 chr2 35 0 0 35 View
5017311 chr2 107 48 16 171 View
5017312 chr2 147 5 1 153 View
5017313 chr2 39 91 12 142 View
5017314 chr2 1 0 0 1 View
5017315 chr2 22 5 8 35 View
5017316 chr2 99 20 37 156 View
5017317 chr2 847 202 225 1274 View
5017318 chr2 1811 557 373 2741 View
5017319 chr2 727 4 0 731 View
5017320 chr2 206 16 40 262 View
5017321 chr2 24 15 1 40 View
5017322 chr2 9 4 0 13 View
5017323 chr2 10 1 0 11 View
5017324 chr2 196 1 2 199 View

Target gene [NCK2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048
Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE226620 scRNA-seq 30 HiSeq X Ten (Homo sapiens)
GSE40774 Expression array 134 Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE139324 scRNA-seq 63 Illumina NextSeq 500 (Homo sapiens)
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE164690 scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026
ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE183048 - NCK2 peak across samples

Peak Plot


> Dataset: GSE143026 - NCK2 peak across samples

Peak Plot