HPV Target gene Detail Information

> P3H2 Gene Search Result


Gene Information
Gene Name P3H2
Gene ID 55214
Gene Full Name prolyl 3-hydroxylase 2
Gene Alias LEPREL1|MCVD|MLAT4
Transcripts ENSG00000090530
Virus HPV
Gene Type protein-coding
HPA Location Info Golgi apparatus;Nucleoplasm, Vesicles, Cytosol;Intracellular and membrane;
Membrane Info Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q8IVL5
HGNC ID HGNC:19317
OMIM ID 610341
Summary This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Target gene [P3H2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000378 chr3 149 51 52 252 View
5000424 chr3 118 51 46 215 View
5000425 chr3 195 19 1 215 View
5000451 chr3 100 54 39 193 View
5000452 chr3 100 55 38 193 View
5000515 chr3 78 50 25 153 View
5000544 chr3 72 50 18 140 View
5001849 chr3 19 1 1 21 View
5004202 chr3 0 1 0 1 View
5005935 chr3 6 7 3 16 View
5006227 chr3 0 0 0 0 View
5007043 chr3 0 0 0 0 View
5007044 chr3 42 12 52 106 View
5007045 chr3 40 11 53 104 View
5007046 chr3 0 0 0 0 View
5007047 chr3 11 1 1 13 View
5009882 chr3 24 3 1 28 View
5009883 chr3 4 0 0 4 View
5013485 chr3 14 1 0 15 View
5013486 chr3 14 1 0 15 View
5013487 chr3 16 1 0 17 View
5013488 chr3 221 869 453 1543 View
5013489 chr3 2066 268 202 2536 View
5013490 chr3 319 19 7 345 View
5013491 chr3 61 21 32 114 View
5015883 chr3 224 72 63 359 View
5015884 chr3 336 6 51 393 View
5015885 chr3 6 1 1 8 View
5015886 chr3 14 5 0 19 View
5015887 chr3 70 32 0 102 View
5017567 chr3 7 3 6 16 View
5017568 chr3 57 3 38 98 View

Target gene [P3H2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048 		Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE139324 scRNA-seq 63 Illumina NextSeq 500 (Homo sapiens)
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE164690 scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE197461 scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE183048 - P3H2 peak across samples

Peak Plot

> Dataset: GSE143026 - P3H2 peak across samples

Peak Plot