Gene Name	PCP4
Gene ID	5121
Gene Full Name	Purkinje cell protein 4
Gene Alias	PEP-19
Transcripts	ENSG00000183036
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm, Nucleoli fibrillar center;
Membrane Info	Predicted intracellular proteins
Uniport_ID	P48539
HGNC ID	HGNC:8742
OMIM ID	601629
Summary	Enables calcium ion binding activity and calmodulin binding activity. Involved in positive regulation of CAMKK-AMPK signaling cascade and positive regulation of neuron differentiation. Located in cytosol and nucleus. Part of protein-containing complex. Biomarker of Huntington's disease and leiomyoma. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5002862	chr21	7	0	0	7	View
5003002	chr21	5	1	0	6	View
5004088	chr21	0	1	0	1	View
5004089	chr21	0	1	0	1	View
5004090	chr21	0	1	0	1	View
5004520	chr21	0	0	0	0	View
5004521	chr21	0	0	0	0	View
5008081	chr21	11	1	0	12	View
5015713	chr21	15	3	0	18	View
5015714	chr21	0	1	1	2	View
5015715	chr21	0	1	0	1	View
5015716	chr21	9	1	0	10	View

Data ID	Experiment type	Sample number	Platform
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE138080	Expression array	35	Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
E   TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
S   GSE197461	scRNA-seq	16	Illumina NovaSeq 6000 (Homo sapiens)
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Expression profiling
• scRNA data
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: TCGA_CESC - PCP4 expression across samples

Volcano Plot

Bar Plot