Gene Name	PDGFD
Gene ID	80310
Gene Full Name	platelet derived growth factor D
Gene Alias	IEGF|MSTP036|SCDGF-B|SCDGFB
Transcripts	ENSG00000170962
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Golgi apparatus, Vesicles;Secreted to blood;
Membrane Info	Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins
Uniport_ID	Q9GZP0
HGNC ID	HGNC:30620
OMIM ID	609673
Summary	The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5002600	chr11	2	7	0	9	View
5004731	chr11	2	7	0	9	View
5006431	chr11	2	7	0	9	View
5006433	chr11	0	1	0	1	View
5006438	chr11	0	1	0	1	View
5007156	chr11	15	0	0	15	View
5007157	chr11	7	7	2	16	View
5014826	chr11	67	22	25	114	View

Data ID	Experiment type	Sample number	Platform
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE139324	scRNA-seq	63	Illumina NextSeq 500 (Homo sapiens)
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE197461	scRNA-seq	16	Illumina NovaSeq 6000 (Homo sapiens)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
E   M   TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Expression profiling
• Methylation profiling
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: TCGA_CESC - PDGFD expression across samples

Volcano Plot

Bar Plot