Gene Name	PVT1
Gene ID	5820
Gene Full Name	Pvt1 oncogene
Gene Alias	LINC00079|MIR1204HG|NCRNA00079|TP53LC09|onco-lncRNA-100
Transcripts	ENSG00000249859
Virus	HPV
Gene Type	ncRNA
HGNC ID	HGNC:9709
OMIM ID	165140
lncRNASNP2 ID	PVT1
Summary	This gene represents a long non-coding RNA locus that has been identified as a candidate oncogene. Increased copy number and overexpression of this gene are associated with many types of cancers including breast and ovarian cancers, acute myeloid leukemia and Hodgkin lymphoma. Allelic variants of this gene are also associated with end-stage renal disease attributed to type 1 diabetes. Consistent with its association with various types of cancer, transcription of this gene is regulated by the tumor suppressor p53 through a canonical p53-binding site, and it has been implicated in regulating levels of the proto-oncogene MYC to promote tumorigenesis. [provided by RefSeq, Sep 2015]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5000628	chr8	59	22	33	114	View
5001151	chr8	1	34	12	47	View
5001227	chr8	38	4	0	42	View
5001421	chr8	12	21	1	34	View
5002687	chr8	5	3	0	8	View
5004928	chr8	46	87	1	134	View
5007175	chr8	19	6	0	25	View
5007176	chr8	1	3	0	4	View
5007177	chr8	60	101	190	351	View
5007178	chr8	7	0	0	7	View
5007179	chr8	201	11	20	232	View
5007180	chr8	44	39	0	83	View
5007181	chr8	13	0	0	13	View
5007182	chr8	65	70	26	161	View
5009847	chr8	130	1	0	131	View
5009848	chr8	73	6	0	79	View
5009849	chr8	78	0	3	81	View
5009850	chr8	16	0	0	16	View
5009851	chr8	50	5	0	55	View
5009852	chr8	12	15	1	28	View
5009853	chr8	9	11	0	20	View
5009854	chr8	2	0	0	2	View
5009855	chr8	1	4	11	16	View
5009856	chr8	27	4	16	47	View
5010075	chr8	17	1	22	40	View
5010237	chr8	180	2	0	182	View
5010412	chr8	3	0	0	3	View
5013794	chr8	13	10	2	25	View
5013795	chr8	390	169	73	632	View
5013796	chr8	2048	1731	974	4753	View
5013797	chr8	2105	1740	964	4809	View
5013798	chr8	3568	1609	511	5688	View
5013799	chr8	3604	1563	503	5670	View
5013800	chr8	3730	1162	478	5370	View
5013801	chr8	3729	1150	479	5358	View
5013802	chr8	2353	578	111	3042	View
5013803	chr8	2361	557	100	3018	View
5013805	chr8	2430	388	70	2888	View
5013806	chr8	2433	302	52	2787	View
5013807	chr8	2430	299	51	2780	View
5013808	chr8	432	4	0	436	View
5013809	chr8	986	243	140	1369	View
5013810	chr8	938	400	264	1602	View
5013811	chr8	387	20	0	407	View
5013812	chr8	727	157	85	969	View
5013814	chr8	647	157	86	890	View
5013815	chr8	33	26	4	63	View
5013816	chr8	33	26	4	63	View
5013817	chr8	614	48	160	822	View
5013818	chr8	502	57	14	573	View
5013819	chr8	501	57	14	572	View
5013820	chr8	24	18	15	57	View
5013821	chr8	24	18	15	57	View
5013822	chr8	24	18	15	57	View
5013823	chr8	109	2	0	111	View
5013824	chr8	3	1	0	4	View
5013825	chr8	256	850	620	1726	View
5013826	chr8	105	1	1	107	View
5013827	chr8	335	8	26	369	View
5013828	chr8	324	10	25	359	View
5013829	chr8	53	2	5	60	View
5013830	chr8	13	12	25	50	View
5013831	chr8	13	12	25	50	View
5013832	chr8	4	1	0	5	View
5013833	chr8	12	18	2	32	View
5013834	chr8	18	21	2	41	View
5013835	chr8	20	21	2	43	View
5013836	chr8	55	7	1	63	View
5013837	chr8	162	13	9	184	View
5013838	chr8	2	5	0	7	View
5013839	chr8	304	164	92	560	View
5013840	chr8	163	2	2	167	View
5013841	chr8	16	19	7	42	View
5013842	chr8	78	9	1	88	View
5013843	chr8	264	27	21	312	View
5013844	chr8	10	5	4	19	View
5016385	chr8	120	10	3	133	View
5016386	chr8	15	1	0	16	View
5016387	chr8	424	166	63	653	View
5016388	chr8	106	39	71	216	View
5016389	chr8	60	6	1	67	View
5016390	chr8	261	47	1	309	View
5016391	chr8	54	14	25	93	View
5016392	chr8	759	780	646	2185	View
5016393	chr8	34	4	0	38	View
5016394	chr8	10	0	0	10	View
5016395	chr8	45	47	50	142	View
5016396	chr8	193	12	8	213	View
5016397	chr8	266	16	1	283	View
5016398	chr8	656	330	284	1270	View
5016399	chr8	243	23	0	266	View
5016400	chr8	447	25	0	472	View
5016401	chr8	34	68	158	260	View
5016402	chr8	454	164	50	668	View
5016403	chr8	472	227	59	758	View
5016404	chr8	436	878	232	1546	View
5016405	chr8	418	890	248	1556	View
5016406	chr8	24	38	1	63	View
5016407	chr8	61	11	13	85	View
5016408	chr8	29	0	0	29	View
5016409	chr8	126	5	1	132	View
5016410	chr8	9	0	0	9	View
5016813	chr8	9	0	0	9	View
5016814	chr8	9	0	0	9	View
5016815	chr8	9	0	0	9	View
5016816	chr8	9	0	0	9	View
5016817	chr8	37	27	3	67	View
5016818	chr8	136	50	45	231	View
5016819	chr8	36	358	21	415	View
5016820	chr8	37	359	22	418	View
5016821	chr8	38	359	22	419	View
5016822	chr8	24	264	16	304	View
5016823	chr8	53	50	50	153	View
5016824	chr8	453	26	1	480	View
5016825	chr8	40	24	5	69	View
5016826	chr8	37	1	0	38	View
5016827	chr8	237	20	0	257	View
5017804	chr8	2	13	5	20	View
5017809	chr8	114	16	24	154	View
5017810	chr8	25	15	0	40	View
5017811	chr8	262	50	1	313	View
5017812	chr8	262	48	1	311	View

Data ID	Experiment type	Sample number	Platform
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE226620	scRNA-seq	30	HiSeq X Ten (Homo sapiens)
GSE40774	Expression array	134	Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE139324	scRNA-seq	63	Illumina NextSeq 500 (Homo sapiens)
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE164690	scRNA-seq	51	Illumina NextSeq 500 (Homo sapiens)
GSE138080	Expression array	35	Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE183048 - PVT1 peak across samples

Peak Plot

> Dataset: GSE143026 - PVT1 peak across samples

Peak Plot