Gene Information
|
Gene Name
|
SUMO2 |
|
Gene ID
|
6613
|
|
Gene Full Name
|
small ubiquitin like modifier 2 |
|
Gene Alias
|
HSMT3|SMT3B|SMT3H2|SUMO3|Smt3A |
|
Transcripts
|
ENSG00000188612
|
|
Virus
|
KSHV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nuclear bodies;Calyx, Connecting piece, Flagellar centriole;
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
P61956
|
|
HGNC ID
|
HGNC:11125
|
|
OMIM ID
|
603042 |
|
Summary
|
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
Target gene [SUMO2] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
23990779 |
H145L |
RTA
|
ORF50
|
Cell line
|
R
T
|
View |
Target gene [SUMO2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE232843
|
RNA-seq |
12 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE79029
|
RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
C GSE202670
|
Chip-seq |
14 |
Illumina Genome Analyzer (Homo sapiens) |
|
GSE280380
|
RNA-seq |
54 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE158935
|
RNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE147063
|
Chip-seq;GRO-seq;4C-seq |
10 |
Illumina NextSeq 500 (Homo sapiens);Illumina Hiseq 2500 (Homo sapiens) |
|
GSE207589
|
RNA-seq |
12 |
Illumina HiSeq 2000 (Homo sapiens) |
|
GSE241095
|
RNA-seq |
44 |
Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE135740
|
Chip-seq |
10 |
Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
|
C GSE52421
|
Chip-seq |
18 |
Illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE280006
|
RNA-seq |
14 |
NextSeq 550 (Homo sapiens) |
|
C GSE38411
|
Chip-seq |
5 |
Illumina Genome Analyzer II (Homo sapiens);Illumina Genome Analyzer II (Human herpesvirus 8) |
|
GSE260925
|
RNA-seq |
24 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE56144
|
Chip-seq;RNA-seq |
33 |
Illumina Genome Analyzer II (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE202670 - SUMO2 peak across samples
|
Peak Plot
|
> Dataset: GSE135740 - SUMO2 peak across samples
|
Peak Plot
|
> Dataset: GSE52421 - SUMO2 peak across samples
|
Peak Plot
|
> Dataset: GSE38411 - SUMO2 peak across samples
|
Peak Plot
|
> Dataset: GSE56144 - SUMO2 peak across samples
|
Peak Plot
|
|
|