All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Carcinoma, Hepatocellular-29434654
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 29434654 L21S
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
2 29434654 L42S
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
3 29434654 S124P
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
4 29434654 L21F
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
5 29434654 L30S
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
6 29434654 L42F
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
7 29434654 N123D
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
8 29434654 Q118X
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
9 29434654 Q118R
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
10 29434654 S124F
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
11 29434654 W4R
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
12 29434654 A60V
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
13 29434654 E54K
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
14 29434654 G102R
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
15 29434654 G35R
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
16 29434654 H51P
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
17 29434654 H51R
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
18 29434654 I126T
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
19 29434654 I84T
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
20 29434654 L213F
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
21 29434654 L213I
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
22 29434654 L213T
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
23 29434654 N98K
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
24 29434654 N98T
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
25 29434654 S5A
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
26 29434654 S5P
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
27 29434654 S5T
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
28 29434654 W182X
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
29 29434654 W77X
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
30 29434654 W77R
PreS
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
31 29434654 Y200F
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
32 29434654 Y200S
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
33 29434654 Y206C
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
34 29434654 Y206H
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
35 29434654 Y206S
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
36 29434654 I126S
S
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.