All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Carcinoma, Hepatocellular-33381105
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 33381105 D144A
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
2 33381105 D144E
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
3 33381105 D144G
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
4 33381105 G130N
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
5 33381105 G130R
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
6 33381105 G145A
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
7 33381105 I126N
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
8 33381105 K141E
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
9 33381105 K141I
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
10 33381105 M133I
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
11 33381105 M133L
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
12 33381105 P120L
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
13 33381105 P120Q
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
14 33381105 P120S
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
15 33381105 P142L
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
16 33381105 P142S
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
17 33381105 Q129H
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
18 33381105 Q129N
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
19 33381105 S143L
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
20 33381105 T126N
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
21 33381105 A1762T
BCP
Carcinoma, Hepatocellular
G
R
S
L
View
22 33381105 C1653T
EnhII
Carcinoma, Hepatocellular
G
R
S
L
View
23 33381105 G1764A
BCP
Carcinoma, Hepatocellular
G
R
S
L
View
24 33381105 T1753V
BCP
Carcinoma, Hepatocellular
G
R
S
L
View
25 33381105 G145R
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
26 33381105 I126S
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
27 33381105 M133T
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
28 33381105 Q129R
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
29 33381105 T126S
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
30 33381105 A181T
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
31 33381105 A181V
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
32 33381105 L180M
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
33 33381105 M204I
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
34 33381105 M204V
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
35 33381105 M250V
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
36 33381105 N236T
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
37 33381105 S202G
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
38 33381105 S202I
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
39 33381105 T184G
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
40 33381105 T184S
RT
P
Carcinoma, Hepatocellular
D
G
R
S
L
View
41 33381105 I126A
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
42 33381105 P120T
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
43 33381105 T126A
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
44 33381105 T143L
S
S
Carcinoma, Hepatocellular
G
R
S
I
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.