All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-31248149
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 31248149 E125Q
RT
P
Hepatitis B Virus Infection
G
R
C
L
View
2 31248149 H122N
RT
P
Hepatitis B Virus Infection
G
R
C
L
View
3 31248149 H271Y
RT
P
Hepatitis B Virus Infection
D
G
R
C
L
View
4 31248149 L129M
RT
P
Hepatitis B Virus Infection
D
G
R
C
L
View
5 31248149 N122H
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
6 31248149 N76D
RT
P
Hepatitis B Virus Infection
D
G
R
C
L
View
7 31248149 P109S
RT
P
Hepatitis B Virus Infection
D
G
R
C
L
View
8 31248149 Q125E
RT
P
Hepatitis B Virus Infection
D
G
R
C
L
View
9 31248149 S105T
RT
P
Hepatitis B Virus Infection
D
G
R
C
L
View
10 31248149 V253I
RT
P
Hepatitis B Virus Infection
D
G
R
C
L
View
11 31248149 V266I
RT
P
Hepatitis B Virus Infection
D
G
R
C
L
View
12 31248149 V266R
RT
P
Hepatitis B Virus Infection
D
G
R
C
L
View
13 31248149 H271C
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
14 31248149 I121N
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
15 31248149 I163V
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
16 31248149 L140P
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
17 31248149 L217R
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
18 31248149 L220I
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
19 31248149 M129L
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
20 31248149 N238H
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
21 31248149 P237H
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
22 31248149 R110G
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
23 31248149 R138E
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
24 31248149 R138K
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
25 31248149 R242K
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
26 31248149 R280S
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
27 31248149 S117C
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
28 31248149 S117Y
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
29 31248149 T128I
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
30 31248149 T128S
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
31 31248149 T225I
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
32 31248149 T259S
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
33 31248149 V142A
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
34 31248149 V278I
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
35 31248149 W153R
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
36 31248149 Y126H
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
37 31248149 K270R
P
P
Hepatitis B Virus Infection
D
G
R
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.