All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B Virus Infection-34902556
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 34902556 2919_3041del
X;P
X;P
Hepatitis B Virus Infection
G
R
C
L
View
2 34902556 G1896A
PreC
C
Hepatitis B Virus Infection
G
R
C
L
View
3 34902556 A1762T
BCP
Hepatitis B Virus Infection
G
R
C
L
View
4 34902556 G1764A
BCP
Hepatitis B Virus Infection
G
R
C
L
View
5 34902556 G145R
S
S
Hepatitis B Virus Infection
G
R
I
C
L
View
6 34902556 T123N
S
S
Hepatitis B Virus Infection
G
R
I
C
L
View
7 34902556 2907_2984del
X;P
X;P
Hepatitis B Virus Infection
G
R
C
L
View
8 34902556 38_54del
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
L
View
9 34902556 40_54del
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
L
View
10 34902556 41_52del
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
L
View
11 34902556 43_54del
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
L
View
12 34902556 A2234C
C
C
Hepatitis B Virus Infection
G
R
C
L
View
13 34902556 A2237C
C
C
Hepatitis B Virus Infection
G
R
C
L
View
14 34902556 A2239C
C
C
Hepatitis B Virus Infection
G
R
C
L
View
15 34902556 A2240G
C
C
Hepatitis B Virus Infection
G
R
C
L
View
16 34902556 A2404C
C
C
Hepatitis B Virus Infection
G
R
C
L
View
17 34902556 A2431G
C
C
Hepatitis B Virus Infection
G
R
C
L
View
18 34902556 A2441G
C
C
Hepatitis B Virus Infection
G
R
C
L
View
19 34902556 A2442G
C
C
Hepatitis B Virus Infection
G
R
C
L
View
20 34902556 A2467G
C
C
Hepatitis B Virus Infection
G
R
C
L
View
21 34902556 A954G
P
P
Hepatitis B Virus Infection
G
R
C
L
View
22 34902556 C154A
PreS2
S
Hepatitis B Virus Infection
G
R
C
L
View
23 34902556 C17S
X
X
Hepatitis B Virus Infection
G
R
C
L
View
24 34902556 C1977A
PreC
C
Hepatitis B Virus Infection
G
R
C
L
View
25 34902556 C2048T
C
C
Hepatitis B Virus Infection
G
R
C
L
View
26 34902556 C2049A
C
C
Hepatitis B Virus Infection
G
R
C
L
View
27 34902556 C2063A
PreC
C
Hepatitis B Virus Infection
G
R
C
L
View
28 34902556 C2429A
C
C
Hepatitis B Virus Infection
G
R
C
L
View
29 34902556 C2430G
C
C
Hepatitis B Virus Infection
G
R
C
L
View
30 34902556 C2440A
C
C
Hepatitis B Virus Infection
G
R
C
L
View
31 34902556 C2730T
P
P
Hepatitis B Virus Infection
G
R
C
L
View
32 34902556 E142A
C
C
Hepatitis B Virus Infection
G
R
C
L
View
33 34902556 E142Q
C
C
Hepatitis B Virus Infection
G
R
C
L
View
34 34902556 F254S
S
S
Hepatitis B Virus Infection
G
R
C
L
View
35 34902556 G1230C
P
P
Hepatitis B Virus Infection
G
R
C
L
View
36 34902556 G1263T
P
P
Hepatitis B Virus Infection
G
R
C
L
View
37 34902556 G1424C
X
X
Hepatitis B Virus Infection
G
R
C
L
View
38 34902556 G1482T
X
X
Hepatitis B Virus Infection
G
R
C
L
View
39 34902556 G2235A
C
C
Hepatitis B Virus Infection
G
R
C
L
View
40 34902556 G2237C
C
C
Hepatitis B Virus Infection
G
R
C
L
View
41 34902556 G2462C
C
C
Hepatitis B Virus Infection
G
R
C
L
View
42 34902556 G3039A
X
X
Hepatitis B Virus Infection
G
R
C
L
View
43 34902556 G711A
P
P
Hepatitis B Virus Infection
G
R
C
L
View
44 34902556 H355N
P
P
Hepatitis B Virus Infection
G
R
C
L
View
45 34902556 K55R
C
C
Hepatitis B Virus Infection
G
R
C
L
View
46 34902556 L84I
PreC
C
Hepatitis B Virus Infection
G
R
C
L
View
47 34902556 N174K
PreS2
S
Hepatitis B Virus Infection
G
R
C
L
View
48 34902556 N42G
C
C
Hepatitis B Virus Infection
G
R
C
L
View
49 34902556 P50Y
C
C
Hepatitis B Virus Infection
G
R
C
L
View
50 34902556 Q206R
C
C
Hepatitis B Virus Infection
G
R
C
L
View
51 34902556 R141Q
C
C
Hepatitis B Virus Infection
G
R
C
L
View
52 34902556 R141S
C
C
Hepatitis B Virus Infection
G
R
C
L
View
53 34902556 S55N
PreC
C
Hepatitis B Virus Infection
G
R
C
L
View
54 34902556 T1257G
P
P
Hepatitis B Virus Infection
G
R
C
L
View
55 34902556 T143V
C
C
Hepatitis B Virus Infection
G
R
C
L
View
56 34902556 T150I
P
P
Hepatitis B Virus Infection
G
R
C
L
View
57 34902556 T1970C
C
C
Hepatitis B Virus Infection
G
R
C
L
View
58 34902556 T2170C
C
C
Hepatitis B Virus Infection
G
R
C
L
View
59 34902556 T2582C
P
P
Hepatitis B Virus Infection
G
R
C
L
View
60 34902556 T393C
S
S
Hepatitis B Virus Infection
G
R
C
L
View
61 34902556 T959C
P
P
Hepatitis B Virus Infection
G
R
C
L
View
62 34902556 W52C
C
C
Hepatitis B Virus Infection
G
R
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.