All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: NSP4

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	36539656	T204I	NSP4	ORF1a	Cell line	S L	View
2	38415690	N4D	NSP4	ORF1a	COVID-19 Cell line	G R S	View
3	38415690	V212L	NSP4	ORF1a	COVID-19 Cell line	G R S	View
4	35658876	T492I	NSP4	ORF1a		G S L	View
5	35658876	V167L	NSP4	ORF1a		G S L	View
6	36512569	T8603C	NSP4	ORF1a		G R L	View
7	36512569	A8590G	NSP4	ORF1a		G R L	View
8	36512569	F17L	NSP4	ORF1a		G R L	View
9	36512569	K12K	NSP4	ORF1a		G R L	View
10	35624123	C9430T	NSP4	ORF1a		R	View
11	38476954	T492I	NSP4	ORF1a	COVID-19	G R S L	View
12	35966679	V167L	NSP4	ORF1a	COVID-19	G L	View
13	35966679	T492I	NSP4	ORF1a	COVID-19	G L	View
14	36590492	V167L	NSP4	ORF1a	COVID-19	G R S L	View
15	36590492	T492I	NSP4	ORF1a	COVID-19	G R S L	View
16	37243279	L438P	NSP4	ORF1a	COVID-19	G R S C L	View
17	38605705	A8967C	NSP4	ORF1a	COVID-19	G R S C L	View
18	38605705	K138T	NSP4	ORF1a	COVID-19	G R S C L	View
19	37744926	I110V	NSP4	ORF1a	COVID-19	G R S C L	View
20	37224159	C10029T	NSP4	ORF1a	COVID-19	G R L	View
21	37224159	C8937T	NSP4	ORF1a	COVID-19	G R L	View
22	37224159	C9344T	NSP4	ORF1a	COVID-19	G R L	View
23	37224159	A9424G	NSP4	ORF1a	COVID-19	G R L	View
24	37224159	C9534T	NSP4	ORF1a	COVID-19	G R L	View
25	37224159	C9866T	NSP4	ORF1a	COVID-19	G R L	View
26	37224159	A128V	NSP4	ORF1a	COVID-19	G R L	View
27	37224159	L264F	NSP4	ORF1a	COVID-19	G R L	View
28	37224159	L438F	NSP4	ORF1a	COVID-19	G R L	View
29	37224159	T327I	NSP4	ORF1a	COVID-19	G R L	View
30	37224159	T492I	NSP4	ORF1a	COVID-19	G R L	View
31	37224159	V290V	NSP4	ORF1a	COVID-19	G R L	View
32	38791536	L436S	NSP4	ORF1a	COVID-19	G R L	View
33	32823907	A9744G	NSP4	ORF1a	COVID-19	G R S L	View
34	32823907	Y397C	NSP4	ORF1a	COVID-19	G R S L	View
35	35992703	K12R	NSP4	ORF1a	COVID-19	G L	View
36	35992703	S481L	NSP4	ORF1a	COVID-19	G L	View
37	35992703	T60I	NSP4	ORF1a	COVID-19	G L	View
38	39339912	T3255I	NSP4	ORF1a	COVID-19	G R	View
39	34547443	F308Y	NSP4	ORF1a	COVID-19	G R	View
40	38605705	C8626T	NSP4	ORF1a	COVID-19	G R S C L	View
41	38605705	T9160A	NSP4	ORF1a	COVID-19	G R S C L	View
42	38605705	C9344T	NSP4	ORF1a	COVID-19	G R S C L	View
43	38605705	A9424G	NSP4	ORF1a	COVID-19	G R S C L	View
44	38605705	C9534T	NSP4	ORF1a	COVID-19	G R S C L	View
45	38605705	C10029T	NSP4	ORF1a	COVID-19	G R S C L	View
46	38605705	L264F	NSP4	ORF1a	COVID-19	G R S C L	View
47	38605705	T327I	NSP4	ORF1a	COVID-19	G R S C L	View
48	38605705	T492I	NSP4	ORF1a	COVID-19	G R S C L	View
49	39774959	T492I	NSP4	ORF1a	COVID-19		View
50	39854608	S3149F	NSP4	ORF1a	COVID-19	R L	View
51	35996593	T295I	NSP4	ORF1a	COVID-19	R L	View
52	36008511	D3222N	NSP4	ORF1a	COVID-19	R C L	View
53	36090111	D2907D	NSP4	ORF1a	COVID-19	R C L	View
54	36090111	F3100F	NSP4	ORF1a	COVID-19	R C L	View
55	36090111	L3083L	NSP4	ORF1a	COVID-19	R C L	View
56	36090111	Q2749Q	NSP4	ORF1a	COVID-19	R C L	View
57	36090111	V2776V	NSP4	ORF1a	COVID-19	R C L	View
58	36090111	V2930L	NSP4	ORF1a	COVID-19	R C L	View
59	36090111	Y2677Y	NSP4	ORF1a	COVID-19	R C L	View
60	36841805	T492I	NSP4	ORF1a	COVID-19	R	View
61	35759503	C8986T	NSP4	ORF1a	COVID-19	R L	View
62	38348230	R249K	NSP4	ORF1a	COVID-19	C L	View
63	36672914	T492I	NSP4	ORF1a	COVID-19	C L	View
64	37260697	C1475T	NSP4	ORF1a	COVID-19	R S C L	View
65	37260697	T492I	NSP4	ORF1a	COVID-19	R S C L	View
66	37529147	C88C	NSP4	ORF1a	COVID-19	R S L	View
67	37529147	F39L	NSP4	ORF1a	COVID-19	R S L	View
68	37529147	T327I	NSP4	ORF1a	COVID-19	R S L	View
69	37529147	T492I	NSP4	ORF1a	COVID-19	R S L	View
70	37529147	V290V	NSP4	ORF1a	COVID-19	R S L	View
71	39294134	T295I	NSP4	ORF1a	COVID-19	R S C L	View
72	33932525	E3073A	NSP4	ORF1a	COVID-19	R C L	View
73	32793182	C8782T	NSP4	ORF1a	COVID-19	R	View
74	38483913	A446V	NSP4	ORF1a	COVID-19	L	View
75	38435775	V242I	NSP4	ORF1a	COVID-19	C L	View
76	38435775	T492I	NSP4	ORF1a	COVID-19	C L	View
77	32515358	C8917T	NSP4	ORF1a	COVID-19	R L	View
78	32595354	M33I	NSP4	ORF1a	COVID-19	R L	View
79	32595354	G309C	NSP4	ORF1a	COVID-19	R L	View
80	40157604	T492I	NSP4	ORF1a	Cell line	G	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.