All Curated Mutation Sites in HEV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HEV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

Click the button below to quickly view the viral genes/regions/protein for mutation

Keyword: ORF2

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	25100237	C5933T	ORF2	ORF2	Liver Failure, Acute	G R S C L	View
2	25100237	C6032T	ORF2	ORF2	Liver Failure, Acute	G R S C L	View
3	25100237	C6104T	ORF2	ORF2	Liver Failure, Acute	G R S C L	View
4	25100237	F356L	ORF2	ORF2	Liver Failure, Acute	G R S C L	View
5	25100237	G6098A	ORF2	ORF2	Liver Failure, Acute	G R S C L	View
6	25100237	K350E	ORF2	ORF2	Liver Failure, Acute	G R S C L	View
7	25100237	P259S	ORF2	ORF2	Liver Failure, Acute	G R S C L	View
8	25100237	T6014C	ORF2	ORF2	Liver Failure, Acute	G R S C L	View
9	25100237	6209delT	ORF2	ORF2	Liver Failure, Acute	G R S C L	View
10	40132339	E435D	ORF2	ORF2	HEV Infection	G R C L	View
11	40132339	G490N	ORF2	ORF2	HEV Infection	G R C L	View
12	40132339	L500F	ORF2	ORF2	HEV Infection	G R C L	View
13	40132339	S483T	ORF2	ORF2	HEV Infection	G R C L	View
14	40132339	S497T	ORF2	ORF2	HEV Infection	G R C L	View
15	40132339	S527T	ORF2	ORF2	HEV Infection	G R C L	View
16	40132339	T517S	ORF2	ORF2	HEV Infection	G R C L	View
17	40132339	T529I	ORF2	ORF2	HEV Infection	G R C L	View
18	40132339	V492M	ORF2	ORF2	HEV Infection	G R C L	View
19	34293039	P259S	ORF2	ORF2	HEV Infection	G R S L	View
20	33877740	P76L	ORF2	ORF2	HEV Infection	G R I C L	View
21	33877740	S68L	ORF2	ORF2	HEV Infection	G R C L	View
22	34293039	L477T	ORF2	ORF2	HEV Infection	G R S I L	View
23	34293039	L613T	ORF2	ORF2	HEV Infection	G R S I L	View
24	35969792	A64T	ORF2	ORF2	Chronic Hepatitis E Cell line	D G R L	View
25	35969792	G38S	ORF2	ORF2	Chronic Hepatitis E Cell line	D G R L	View
26	35969792	G71R	ORF2	ORF2	Chronic Hepatitis E Cell line	D G R L	View
27	35969792	P79S	ORF2	ORF2	Chronic Hepatitis E Cell line	D G R I L	View
28	35969792	S95P	ORF2	ORF2	Chronic Hepatitis E Cell line	D G R L	View
29	35969792	T324S	ORF2	ORF2	Chronic Hepatitis E Cell line	D G R L	View
30	35969792	V245I	ORF2	ORF2	Chronic Hepatitis E Cell line	D G R L	View
31	21152284	A606V	ORF2	ORF2	Cell line	G R L	View
32	21152284	L614M	ORF2	ORF2	Cell line	G R L	View
33	21152284	M614L	ORF2	ORF2	Cell line	G R	View
34	21152284	V606A	ORF2	ORF2	Cell line	G R	View
35	23054435	53delI	ORF2	ORF2	Acute Viral Hepatitis Liver Failure, Acute	G R S C L	View
36	33335573	N562C	ORF2	ORF2	Acute Viral Hepatitis	G R I	View
37	33335573	N562K	ORF2	ORF2	Acute Viral Hepatitis	G R I	View
38	33335573	N562L	ORF2	ORF2	Acute Viral Hepatitis	G R	View

Contents
Description

The table shows all curated mutation sites of HEV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.