All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: ORF6

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	33097660	M58R	ORF6	ORF6	Cell line	S	View
2	37796123	D61L	ORF6	ORF6	COVID-19 Cell line	G R	View
3	37738983	D61L	ORF6	ORF6	COVID-19 Cell line	G R S	View
4	35764775	T21I	ORF6	ORF6		L	View
5	35764775	W27L	ORF6	ORF6		L	View
6	38283360	I33T	ORF6	ORF6		R	View
7	38283360	V24A	ORF6	ORF6		R	View
8	38283360	V9F	ORF6	ORF6		R T	View
9	38283360	W27L	ORF6	ORF6		R	View
10	36755883	D61L	ORF6	ORF6	COVID-19	G R L	View
11	38763300	D61L	ORF6	ORF6	COVID-19	G R S L	View
12	36310647	D61H	ORF6	ORF6	COVID-19	G R S	View
13	37224159	A27259C	ORF6	ORF6	COVID-19	G R L	View
14	37224159	GAT27382CTC	ORF6	ORF6	COVID-19	G R L	View
15	37224159	D61L	ORF6	ORF6	COVID-19	G R L	View
16	37224159	M19M	ORF6	ORF6	COVID-19	G R L	View
17	37529147	M19M	ORF6	ORF6	COVID-19	G R S L	View
18	36090111	1delM	ORF6	ORF6	COVID-19	R C L	View
19	36841805	D61L	ORF6	ORF6	COVID-19	R	View
20	33384909	K23S	ORF6	ORF6	COVID-19	R	View
21	33384909	R20S	ORF6	ORF6	COVID-19	R	View
22	37903828	I14T	ORF6	ORF6	COVID-19	R L	View
23	37903828	S41P	ORF6	ORF6	COVID-19	R L	View
24	37903828	D61L	ORF6	ORF6	COVID-19	R L	View
25	37903828	K42N	ORF6	ORF6	COVID-19	R L	View
26	37903828	P57L	ORF6	ORF6	COVID-19	R L	View
27	37903828	S43P	ORF6	ORF6	COVID-19	R L	View
28	37903828	W27L	ORF6	ORF6	COVID-19	R L	View
29	37903828	E13D	ORF6	ORF6	COVID-19	R L	View
30	36057416	T27299C	ORF6	ORF6	COVID-19	R L	View
31	36057416	I33T	ORF6	ORF6	COVID-19	R L	View
32	40063870	L4I	ORF6	ORF6	COVID-19	R L	View
33	38632523	A27259C	ORF6	ORF6	COVID-19	G R L	View
34	38632523	G27382C	ORF6	ORF6	COVID-19	G R L	View
35	38632523	A37383T	ORF6	ORF6	COVID-19	G R L	View
36	38632523	T27384C	ORF6	ORF6	COVID-19	G R L	View
37	38632523	D61L	ORF6	ORF6	COVID-19	G R L	View
38	37192725	D61L	ORF6	ORF6	Cell line	G R S I L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.