All Curated Mutation Sites in HCMV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HCMV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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Click the button below to quickly view the viral genes/regions/protein for mutation

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gB
  
IE2
  
Pol
  
protease
  
UL18
  
UL27
  
UL54
  
UL56
  
UL89
  
UL97
  
US28
  

Keyword: Pol
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 17157554 D413A
Pol
UL54
Cytomegalovirus infections
D
C
View
2 17709468 G841A
Pol
UL54
Cytomegalovirus infections
D
View
3 17709468 L845P
Pol
UL54
Cytomegalovirus infections
View
4 17709468 T813S
Pol
UL54
Cytomegalovirus infections
D
View
5 18419454 L776M
Pol
UL54
Cytomegalovirus infections
D
C
View
6 32726419 D588N
Pol
UL54
Cytomegalovirus infections
D
View
7 17043128 A834P
Pol
UL54
Cytomegalovirus infections
D
R
View
8 17043128 L737M
Pol
UL54
Cytomegalovirus infections
R
View
9 17043128 N408K
Pol
UL54
Cytomegalovirus infections
D
R
View
10 9125039 C2160T
Pol
UL54
Cytomegalovirus Retinitis
Encephalitis
D
R
View
11 9125039 L501F
Pol
UL54
Cytomegalovirus Retinitis
Encephalitis
D
R
View
12 8627655 T700A
Pol
UL54
HCMV-HIV Coinfeciton
D
R
View
13 8627655 V715M
Pol
UL54
HCMV-HIV Coinfeciton
D
R
View
14 20587851 K805Q
Pol
UL54
HCMV-HIV Coinfeciton
D
View
15 20587851 T821I
Pol
UL54
HCMV-HIV Coinfeciton
D
View
16 9697736 A809V
Pol
UL54
HCMV-HIV Coinfeciton
Cytomegalovirus Retinitis
D
R
C
View
17 8381637 C3619G
Pol
UL54
Cell line
D
R
View
18 8381637 G987A
Pol
UL54
Cell line
D
R
View
19 9721246 K513N
Pol
UL54
Cell line
D
R
View
20 9721246 V812L
Pol
UL54
Cell line
D
R
View
21 12525621 V823A
Pol
UL54
Cell line
D
R
View
22 12525621 V824L
Pol
UL54
Cell line
D
R
View
23 15980340 981_982del
Pol
UL54
Cell line
D
R
View
24 17197042 N495K
Pol
UL54
Cell line
D
R
View
25 17197042 T700A
Pol
UL54
Cell line
D
R
View
26 17197042 V715M
Pol
UL54
Cell line
D
R
View
27 17942550 D413A
Pol
UL54
Cell line
R
View
28 18502683 I521T
Pol
UL54
Cell line
D
R
View
29 18502683 P522A
Pol
UL54
Cell line
D
R
View
30 18502683 P522L
Pol
UL54
Cell line
R
View
31 18502683 P522S
Pol
UL54
Cell line
D
R
View
32 21295516 A714V
Pol
UL54
Cell line
View
33 21295516 A809V
Pol
UL54
Cell line
D
View
34 21295516 A885T
Pol
UL54
Cell line
View
35 21295516 A987G
Pol
UL54
Cell line
D
View
36 21295516 C304S
Pol
UL54
Cell line
View
37 21295516 D588N
Pol
UL54
Cell line
D
View
38 21295516 E756K
Pol
UL54
Cell line
D
View
39 21295516 F412C
Pol
UL54
Cell line
D
View
40 21295516 F412L
Pol
UL54
Cell line
D
View
41 21295516 F412S
Pol
UL54
Cell line
D
View
42 21295516 F412V
Pol
UL54
Cell line
D
View
43 21295516 L545S
Pol
UL54
Cell line
D
View
44 21295516 L545W
Pol
UL54
Cell line
D
View
45 21295516 N408K
Pol
UL54
Cell line
D
View
46 21295516 N685S
Pol
UL54
Cell line
View
47 21295516 N898D
Pol
UL54
Cell line
View
48 21295516 P522S
Pol
UL54
Cell line
D
View
49 21295516 Q578H
Pol
UL54
Cell line
D
View
50 21295516 S655L
Pol
UL54
Cell line
View
51 21295516 S897L
Pol
UL54
Cell line
View
52 21295516 V544A
Pol
UL54
Cell line
View
53 21295516 V781I
Pol
UL54
Cell line
D
View
54 21968367 A809V
Pol
UL54
Cell line
D
View
55 21968367 A834P
Pol
UL54
Cell line
D
View
56 21968367 A987G
Pol
UL54
Cell line
D
View
57 21968367 E756D
Pol
UL54
Cell line
D
View
58 21968367 E756K
Pol
UL54
Cell line
D
View
59 21968367 F412L
Pol
UL54
Cell line
D
View
60 21968367 G841A
Pol
UL54
Cell line
D
View
61 21968367 L545W
Pol
UL54
Cell line
D
View
62 21968367 M844T
Pol
UL54
Cell line
D
View
63 21968367 M844V
Pol
UL54
Cell line
D
View
64 21968367 N408K
Pol
UL54
Cell line
D
View
65 21968367 P522A
Pol
UL54
Cell line
D
View
66 21968367 P744T
Pol
UL54
Cell line
View
67 21968367 Q578H
Pol
UL54
Cell line
D
View
68 21968367 T813S
Pol
UL54
Cell line
D
View
69 21968367 V781I
Pol
UL54
Cell line
D
View
70 27044553 N408K
Pol
UL54
Cell line
D
R
View
71 27044553 V812L
Pol
UL54
Cell line
D
R
View
72 32015044 K805Q
Pol
UL54
Cell line
View
73 32015044 Q579I
Pol
UL54
Cell line
View
74 33588012 V715G
Pol
UL54
Cell line
View
75 33588012 V715M
Pol
UL54
Cell line
D
View
76 33588012 V715S
Pol
UL54
Cell line
D
View
77 33563814 A987G
Pol
UL54

View
78 33563814 F412V
Pol
UL54

View
Contents
Description

The table shows all curated mutation sites of HCMV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.