All Curated Mutation Sites in HBV 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
*Please select one option you are interested in, the page will be automatically redirected.
     
     

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: PreS2
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 28859616 N3S
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
2 28859616 M1I
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
3 28859616 M1T
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
4 28859616 M1V
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
5 28859616 A162G
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
6 28859616 F22I
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
7 28859616 F22L
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
8 28859616 L126S
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
9 28859616 L126T
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
10 28859616 T531C
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
11 28859616 T531G
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
12 28859616 T53C
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
13 23029487 Q10R
PreS2
S
HBV-HIV Coinfection
G
S
C
L
View
14 23029487 A53V
PreS2
S
HBV-HIV Coinfection
G
S
C
L
View
15 30835025 M1I
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
16 30835025 M1T
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
17 30835025 M1V
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
18 23029487 R48K
PreS2
S
HBV-HIV Coinfection
G
S
C
L
View
19 23029487 R48T
PreS2
S
HBV-HIV Coinfection
G
S
C
L
View
20 35361141 A11T
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
21 35361141 P52L
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
22 35361141 T7I
PreS2
S
Hepatitis B, Chronic
G
S
C
L
View
23 36325017 A39V
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
24 36325017 F22L
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
25 36325017 F46S
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
26 36325017 I42T
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
27 36325017 N33D
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
28 36325017 P41H
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
29 36325017 P52L
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
30 36325017 R16K
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
31 36325017 R18K
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
32 36325017 T11N
PreS2
S
Hepatitis B, Chronic
G
R
S
C
L
View
33 36970691 T38A
PreS2
S
Hepatitis B, Chronic
G
R
L
View
34 17888035 T53C
PreS2
S
Hepatitis B, Chronic
Carcinoma, Hepatocellular
G
R
L
View
35 17888035 F22L
PreS2
S
Hepatitis B, Chronic
Carcinoma, Hepatocellular
G
R
L
View
36 22720022 F22L
PreS2
S
Hepatitis B-Blood-Borne virus Coinfection
G
S
L
View
37 18939932 M1A
PreS2
S
Carcinoma, Hepatocellular
R
L
View
38 18939932 M1I
PreS2
S
Carcinoma, Hepatocellular
R
L
View
39 18939932 M1V
PreS2
S
Carcinoma, Hepatocellular
R
L
View
40 18939932 Q2K
PreS2
S
Carcinoma, Hepatocellular
R
L
View
41 18939932 Q2R
PreS2
S
Carcinoma, Hepatocellular
R
L
View
42 20699378 T53C
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
43 20962085 M120V
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
T
View
44 20962085 F141L
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
T
View
45 21108338 C135A
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
46 21108338 C135T
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
47 21108338 C1A
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
48 21108338 C1G
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
49 21108338 T105C
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
50 21108338 C105T
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
51 21108338 C52A
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
52 21108338 C52T
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
53 21108338 A109C
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
54 21108338 A109T
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
55 21108338 A10C
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
56 21108338 A10T
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
57 21108338 A49G
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
58 21108338 A49T
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
59 21108338 A7C
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
60 21108338 C31A
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
61 21108338 C31T
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
62 21108338 T53C
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
63 22012717 F141L
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
64 23386590 C10A
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
65 23386590 C31C
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
66 23386590 C31T
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
67 23386590 F141L
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
68 23386590 T53C
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
69 23386590 A1C
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
70 23386590 A1T
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
71 23386590 A135C
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
72 23386590 A31C
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
73 23386590 A31T
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
74 23386590 A52C
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
75 23386590 A52T
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
76 23386590 C109A
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
77 23386590 C109T
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
78 23386590 C2875A
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
T
View
79 23386590 G105C
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
80 23386590 G105T
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
81 23386590 G147C
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
82 23386590 T49A
PreS2
S
Carcinoma, Hepatocellular
G
S
C
L
View
83 23386590 C76A
PreS2
S
Carcinoma, Hepatocellular
G
C
L
T
View
84 23386590 C7A
PreS2
S
Carcinoma, Hepatocellular
G
C
L
T
View
85 24849936 T31C
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
86 24849936 T53C
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
87 25501679 C105T
PreS2
S
Carcinoma, Hepatocellular
C
L
View
88 27486882 P41H
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
89 27486882 P66L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
90 27486882 F75S
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
91 27486882 G99E
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
92 27486882 H114T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
93 27486882 I147T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
94 27486882 I165L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
95 27486882 Q184H
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
96 27727182 F22L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
97 27727182 M1I
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
98 27727182 M1T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
99 27727182 M1V
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
100 27727182 T31C
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
101 27727182 T53C
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
102 32504396 F22L
PreS2
S
Carcinoma, Hepatocellular
G
R
S
C
L
View
103 32504396 T64C
PreS2
S
Carcinoma, Hepatocellular
G
R
S
C
L
View
104 32722114 1_54del
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
105 35390033 I150T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
106 35390033 T125N
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
107 35390033 T125P
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
108 35390033 T125S
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
109 35390033 A130N
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
110 35390033 A130T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
111 35390033 A138D
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
112 35390033 A143V
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
113 35390033 A160P
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
114 35390033 A160T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
115 35390033 D133N
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
116 35390033 F141I
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
117 35390033 F141L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
118 35390033 F141V
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
119 35390033 F165L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
120 35390033 F165S
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
121 35390033 G149E
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
122 35390033 G149K
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
123 35390033 H128L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
124 35390033 I161L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
125 35390033 I161T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
126 35390033 K167T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
127 35390033 L139P
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
128 35390033 L139Q
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
129 35390033 M120I
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
130 35390033 M120V
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
131 35390033 N123K
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
132 35390033 N123T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
133 35390033 N156I
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
134 35390033 N156S
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
135 35390033 N156T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
136 35390033 N174K
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
137 35390033 N174S
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
138 35390033 P134H
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
139 35390033 P134T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
140 35390033 P153L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
141 35390033 P173L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
142 35390033 P173Q
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
143 35390033 Q121K
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
144 35390033 Q121R
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
145 35390033 Q129K
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
146 35390033 Q155H
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
147 35390033 Q155P
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
148 35390033 R135K
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
149 35390033 R137K
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
150 35390033 R137Q
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
151 35390033 S124T
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
152 35390033 S146F
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
153 35390033 S147G
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
154 35390033 S148L
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
155 35390033 S152N
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
156 35390033 T126A
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
157 35390033 T126I
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
158 35390033 T126N
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
159 35390033 T157S
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
160 35390033 T164D
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
161 35390033 T164I
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
162 35390033 T164S
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
163 35390033 T168I
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
164 35390033 V136A
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
165 28376292 F22S
PreS2
S
HBV-HIV Coinfection
G
C
L
View
166 35390033 V158A
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
167 35390033 V172A
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
168 35390033 W122R
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
169 35390033 Y140C
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
170 35390033 Y140F
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
171 35390033 Y140H
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
172 35390033 Y140N
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
173 35390033 Y140S
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
174 36292082 A3205C
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
175 36292082 A3205G
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
176 36292082 F22I
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
177 36292082 M1L
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
178 36292082 M1T
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
179 36292082 M1V
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
180 36292082 T31C
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
181 36292082 T3206C
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
182 36292082 T53C
PreS2
S
Carcinoma, Hepatocellular
G
C
L
View
183 37681020 T2857C
PreS2
S
Carcinoma, Hepatocellular
G
R
C
L
View
184 39986372 F22L
PreS2
S
Carcinoma, Hepatocellular
G
R
S
L
View
185 39986372 T53C
PreS2
S
Carcinoma, Hepatocellular
G
R
S
L
View
186 23272650 L180M
PreS2
S
Carcinoma, Hepatocellular
Hepatitis B, Chronic
Liver Cirrhosis
G
S
C
L
View
187 17503077 A53V
PreS2
S
Liver Diseases
G
L
View
188 17503077 D51G
PreS2
S
Liver Diseases
G
L
View
189 17503077 F46S
PreS2
S
Liver Diseases
G
L
View
190 17503077 I49T
PreS2
S
Liver Diseases
G
L
View
191 17503077 P54L
PreS2
S
Liver Diseases
G
L
View
192 17503077 A39V
PreS2
S
Liver Diseases
G
L
View
193 17503077 P52L
PreS2
S
Liver Diseases
G
L
View
194 17503077 T31A
PreS2
S
Liver Diseases
G
L
View
195 23865777 F22L
PreS2
S
Liver Diseases
G
R
S
C
L
View
196 23865777 I42T
PreS2
S
Liver Diseases
G
R
S
C
L
View
197 23978387 F22L
PreS2
S
Liver Diseases
G
R
S
C
L
View
198 24409056 M1I
PreS2
S
Liver Diseases
G
R
S
L
View
199 24409056 M1T
PreS2
S
Liver Diseases
G
R
S
L
View
200 24409056 F22L
PreS2
S
Liver Diseases
G
R
S
L
View
201 23951004 L54P
PreS2
S
Occult HBV Infection
L
View
202 23951004 V39A
PreS2
S
Occult HBV Infection
L
View
203 27486882 19_22del
PreS2
S
Occult HBV Infection
G
R
C
L
View
204 28332361 A11T
PreS2
S
Occult HBV Infection
R
C
View
205 28332361 D14N
PreS2
S
Occult HBV Infection
R
C
View
206 28332361 F22L
PreS2
S
Occult HBV Infection
R
C
View
207 28332361 G19D
PreS2
S
Occult HBV Infection
R
C
View
208 28332361 G30E
PreS2
S
Occult HBV Infection
R
C
View
209 28332361 I42T
PreS2
S
Occult HBV Infection
R
C
View
210 28332361 N33H
PreS2
S
Occult HBV Infection
R
C
View
211 28332361 P54Q
PreS2
S
Occult HBV Infection
R
C
View
212 28332361 P54T
PreS2
S
Occult HBV Infection
R
C
View
213 28332361 R16K
PreS2
S
Occult HBV Infection
R
C
View
214 35903154 I42T
PreS2
S
Occult HBV Infection
G
R
L
View
215 36257516 D133N
PreS2
S
Occult HBV Infection
G
L
View
216 36257516 H128R
PreS2
S
Occult HBV Infection
G
L
View
217 36257516 I161T
PreS2
S
Occult HBV Infection
G
L
View
218 36257516 Q121K
PreS2
S
Occult HBV Infection
G
I
L
View
219 36257516 Q129K
PreS2
S
Occult HBV Infection
G
L
View
220 36257516 Q132L
PreS2
S
Occult HBV Infection
G
L
View
221 36257516 R135K
PreS2
S
Occult HBV Infection
G
L
View
222 36257516 T126I
PreS2
S
Occult HBV Infection
G
L
View
223 36257516 T168I
PreS2
S
Occult HBV Infection
G
L
View
224 19431214 M1I
PreS2
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
225 19431214 Q2K
PreS2
S
Occult HBV Infection
Carcinoma, Hepatocellular
G
R
C
L
View
226 39062134 A11T
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
227 39062134 A53V
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
228 39062134 A7T
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
229 30943997 A35V
PreS2
S

G
View
230 30943997 A47S
PreS2
S

G
View
231 30943997 N33S
PreS2
S

G
View
232 30943997 N37T
PreS2
S

G
View
233 30943997 T49I
PreS2
S

G
View
234 30943997 T54P
PreS2
S

G
View
235 30943997 V32L
PreS2
S

G
View
236 30943997 V53A
PreS2
S

G
View
237 39062134 I45T
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
238 33803998 F141L
PreS2
S

G
S
I
View
239 39062134 L54S
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
240 39062134 T38I
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
241 39062134 A39V
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
242 39062134 D51V
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
243 39062134 F22L
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
244 39062134 H41L
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
245 39062134 H41P
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
246 39062134 N37T
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
247 39062134 R48T
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
248 39062134 S46F
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
249 39062134 S47L
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
250 39062134 T49I
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
251 39062134 V17I
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
252 39062134 Y21C
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
253 39062134 Y21S
PreS2
S
HBV-HIV Coinfection
G
R
C
L
View
254 10534721 P52L
PreS2
S
Hepatitis B Virus Infection
G
View
255 10534721 R48K
PreS2
S
Hepatitis B Virus Infection
G
View
256 10534721 S44L
PreS2
S
Hepatitis B Virus Infection
G
View
257 19272629 P36L
PreS2
S
Hepatitis B Virus Infection
G
R
C
View
258 20573234 T168A
PreS2
S
Hepatitis B Virus Infection
R
L
View
259 24282423 N123S
PreS2
S
Hepatitis B Virus Infection
View
260 24282423 N15S
PreS2
S
Hepatitis B Virus Infection
View
261 24282423 N177S
PreS2
S
Hepatitis B Virus Infection
View
262 24282423 N320K
PreS2
S
Hepatitis B Virus Infection
View
263 24632784 R16K
PreS2
S
Hepatitis B Virus Infection
G
S
View
264 24632784 R18K
PreS2
S
Hepatitis B Virus Infection
G
S
View
265 25351410 C407A
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
266 25351410 A167G
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
267 25351410 A667T
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
268 25351410 A680C
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
269 25351410 A90V
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
270 25351410 C2990T
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
271 25351410 I218L
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
272 25351410 L213F
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
273 25351410 P127T
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
274 25351410 S162T
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
275 25351410 T3205A
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
276 25351410 T47A
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
View
277 25351410 C3165A
PreS2
S
Hepatitis B Virus Infection
G
R
C
View
278 30584239 M1I
PreS2
S
Hepatitis B Virus Infection
G
R
S
C
L
View
279 30584239 M1V
PreS2
S
Hepatitis B Virus Infection
G
R
S
C
L
View
280 34214504 Q120K
PreS1;PreS2
S
Hepatitis B Virus Infection
D
G
R
S
C
View
281 34902556 38_54del
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
L
View
282 34902556 40_54del
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
L
View
283 34902556 41_52del
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
L
View
284 34902556 43_54del
PreS1;PreS2;S
S
Hepatitis B Virus Infection
G
R
C
L
View
285 34902556 C154A
PreS2
S
Hepatitis B Virus Infection
G
R
C
L
View
286 34902556 N174K
PreS2
S
Hepatitis B Virus Infection
G
R
C
L
View
287 35891356 A47S
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
288 37703117 A11V
PreS2
S
Hepatitis B Virus Infection
G
L
View
289 37703117 F8L
PreS2
S
Hepatitis B Virus Infection
G
L
View
290 37703117 I45T
PreS2
S
Hepatitis B Virus Infection
G
L
View
291 37703117 N33S
PreS2
S
Hepatitis B Virus Infection
G
L
View
292 37703117 N55D
PreS2
S
Hepatitis B Virus Infection
G
L
View
293 37703117 Q2X
PreS2
S
Hepatitis B Virus Infection
G
L
View
294 37703117 S40L
PreS2
S
Hepatitis B Virus Infection
G
L
View
295 37703117 S44P
PreS2
S
Hepatitis B Virus Infection
G
L
View
296 37703117 T49A
PreS2
S
Hepatitis B Virus Infection
G
L
View
297 37703117 T7A
PreS2
S
Hepatitis B Virus Infection
G
L
View
298 37703117 T7K
PreS2
S
Hepatitis B Virus Infection
G
L
View
299 37703117 V32I
PreS2
S
Hepatitis B Virus Infection
G
L
View
300 37703117 V35A
PreS2
S
Hepatitis B Virus Infection
G
L
View
301 35891356 A7Q
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
302 35891356 A7T
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
303 20160279 T31C
PreS2
S
Hepatitis B Virus Infection
Carcinoma, Hepatocellular
L
View
304 35891356 D51G
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
305 31501793 M109T
PreS2
S
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
R
C
L
View
306 31501793 S130L
PreS2
S
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
R
C
L
View
307 31501793 S130F
PreS2
S
Hepatitis B Virus Infection
Liver Cirrhosis
Carcinoma, Hepatocellular
G
R
C
L
View
308 12974898 G149R
PreS2
S
Hepatitis B, Chronic
L
View
309 15953865 12_22del
PreS2
S
Hepatitis B, Chronic
G
R
L
View
310 15953865 23_55del
PreS2
S
Hepatitis B, Chronic
G
R
L
View
311 16847965 N152S
PreS2
S
Hepatitis B, Chronic
G
R
View
312 16847965 N174T
PreS2
S
Hepatitis B, Chronic
G
R
View
313 16847965 P155Q
PreS2
S
Hepatitis B, Chronic
G
R
View
314 17258721 C27A
PreS2
S
Hepatitis B, Chronic
G
R
C
View
315 17258721 C4A
PreS2
S
Hepatitis B, Chronic
G
R
C
View
316 17258721 G53A
PreS2
S
Hepatitis B, Chronic
G
R
C
View
317 17258721 H9Q
PreS2
S
Hepatitis B, Chronic
G
R
C
View
318 17258721 Q2K
PreS2
S
Hepatitis B, Chronic
G
R
C
View
319 17258721 R18K
PreS2
S
Hepatitis B, Chronic
G
R
C
View
320 17258721 S29P
PreS2
S
Hepatitis B, Chronic
G
R
C
View
321 17258721 S85P
PreS2
S
Hepatitis B, Chronic
G
R
C
View
322 17258721 T85C
PreS2
S
Hepatitis B, Chronic
G
R
C
View
323 17825452 A39S
PreS2
S
Hepatitis B, Chronic
G
R
View
324 17825452 A41I
PreS2
S
Hepatitis B, Chronic
G
R
View
325 17825452 A41S
PreS2
S
Hepatitis B, Chronic
G
R
View
326 17825452 F46G
PreS2
S
Hepatitis B, Chronic
G
R
View
327 17825452 F46L
PreS2
S
Hepatitis B, Chronic
G
R
View
328 17825452 H41I
PreS2
S
Hepatitis B, Chronic
G
R
View
329 17825452 H41S
PreS2
S
Hepatitis B, Chronic
G
R
View
330 17825452 I45T
PreS2
S
Hepatitis B, Chronic
G
R
View
331 17825452 L41I
PreS2
S
Hepatitis B, Chronic
G
R
View
332 17825452 L41S
PreS2
S
Hepatitis B, Chronic
G
R
View
333 17825452 L46G
PreS2
S
Hepatitis B, Chronic
G
R
View
334 17825452 N33S
PreS2
S
Hepatitis B, Chronic
G
R
View
335 17825452 P41I
PreS2
S
Hepatitis B, Chronic
G
R
View
336 17825452 P41S
PreS2
S
Hepatitis B, Chronic
G
R
View
337 17825452 S46G
PreS2
S
Hepatitis B, Chronic
G
R
View
338 17825452 V39S
PreS2
S
Hepatitis B, Chronic
G
R
View
339 35891356 I42T
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
340 20119580 F46S
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
341 20119580 A11T
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
342 20119580 F22L
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
343 20119580 N4K
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
344 20119580 T7A
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
345 20119580 H9Q
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
346 20119580 R16P
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
347 20119580 R16G
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
348 20119580 V17P
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
349 20119580 V17A
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
350 20119580 R18S
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
351 20119580 G19S
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
352 20119580 L20Q
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
353 20119580 P54Q
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
354 20119580 I42T
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
355 20119580 P54L
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
356 20119580 V32A
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
357 20119580 I45T
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
358 20119580 T49I
PreS2
S
Hepatitis B, Chronic
G
R
C
L
View
359 19889143 D51G
PreS2
S
HBV-HIV Coinfection
G
R
S
C
View
360 21785721 3018_3202del
PreS1;PreS2
S
Hepatitis B, Chronic
G
S
L
View
361 21785721 3144_56del
PreS1;PreS2
S
Hepatitis B, Chronic
G
S
L
View
362 19889143 H41Q
PreS2
S
HBV-HIV Coinfection
G
R
S
C
View
363 19889143 L20P
PreS2
S
HBV-HIV Coinfection
G
R
S
C
View
364 19889143 S28G
PreS2
S
HBV-HIV Coinfection
G
R
S
C
View
365 19889143 T37A
PreS2
S
HBV-HIV Coinfection
G
R
S
C
View
366 35891356 Q13L
PreS2
S
Acute and Chronic Hepatitis B Virus Infection
G
C
L
View
367 24006435 A135C
PreS2
S
Hepatitis B, Chronic
G
S
C
View
368 24006435 A1C
PreS2
S
Hepatitis B, Chronic
G
S
C
View
369 24006435 A31T
PreS2
S
Hepatitis B, Chronic
G
S
C
View
370 24006435 A52C
PreS2
S
Hepatitis B, Chronic
G
S
C
View
371 24006435 C109A
PreS2
S
Hepatitis B, Chronic
G
S
C
View
372 24006435 C7A
PreS2
S
Hepatitis B, Chronic
G
S
C
View
373 24006435 G105C
PreS2
S
Hepatitis B, Chronic
G
S
C
View
374 24006435 G147C
PreS2
S
Hepatitis B, Chronic
G
S
C
View
375 24006435 T49A
PreS2
S
Hepatitis B, Chronic
G
S
C
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.