All Curated Mutation Sites in HCMV

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HCMV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

Click the button below to quickly view the viral genes/regions/protein for mutation

Keyword: protease

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	9037377	A12T	protease	UL80a	Cytomegalovirus infections	R	View
2	9037377	G47S	protease	UL80a	HCMV-HIV Coinfeciton	R	View
3	9037377	H44Y	protease	UL80a	HCMV-HIV Coinfeciton	R	View
4	9037377	S8P	protease	UL80a	HCMV-HIV Coinfeciton	R	View
5	7559530	A143Q	protease	UL80a	Cell line		View
6	9558326	R165A	protease	UL80a	Cell line		View
7	9558326	R166A	protease	UL80a	Cell line		View
8	8611517	A143Q	protease	UL80a			View
9	8639545	C138A	protease	UL80a		D	View
10	8639545	C161A	protease	UL80a		D	View
11	8676515	V141G	protease	UL80a			View
12	8676515	V207G	protease	UL80a			View
13	9008301	A143V	protease	UL80a			View
14	9008301	S132A	protease	UL80a			View
15	9376371	A143Q	protease	UL80a		R	View
16	9376371	W42F	protease	UL80a		R	View

Contents
Description

The table shows all curated mutation sites of HCMV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.