Gene Information
|
Gene Name
|
AFG2A |
|
Gene ID
|
166378
|
|
Gene Full Name
|
AFG2 AAA ATPase homolog A |
|
Gene Alias
|
AFG2|EHLMRS|NEDHSB|SPAF|SPATA5 |
|
Transcripts
|
ENSG00000145375
|
|
Virus
|
EBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
Q8NB90
|
|
HGNC ID
|
HGNC:18119
|
|
OMIM ID
|
613940 |
|
Summary
|
This gene encodes a member of the ATPase associated with diverse activities family, whose members are defined by a highly conserved ATPase domain. Members of this family participate in diverse cellular processes that include membrane fusion, DNA replication, microtubule severing, and protein degradation. The protein encoded by this gene has a putative mitochondrial targeting sequence and has been proposed to function in maintenance of mitochondrial function and integrity during mouse spermatogenesis. Allelic variants in this gene have been associated with epilepsy, hearing loss, and cognitive disability syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] |
Target gene [AFG2A] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 3000475 |
chr4 |
13 |
3 |
0 |
16 |
View |
Target gene [AFG2A] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE42867
|
Expression array |
12 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
C GSE246060
|
Chip-seq |
26 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE198334
|
Chip-seq |
4 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE100458
|
Expression array |
14 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array [CDF: Brainarray HGU133Plus2_Hs_ENTREZG_v21] |
|
GSE165194
|
RNA-seq |
3 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE246059
|
ATAC-seq |
8 |
Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE225248
|
Chip-seq |
12 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE102203
|
Expression array |
10 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [probe set (exon) version] |
|
GSE85599
|
Expression array |
17 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE181906
|
RNA-seq |
24 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE246060 - AFG2A peak across samples
|
Peak Plot
|
> Dataset: GSE198334 - AFG2A peak across samples
|
Peak Plot
|
> Dataset: GSE246059 - AFG2A peak across samples
|
Peak Plot
|
> Dataset: GSE225248 - AFG2A peak across samples
|
Peak Plot
|
|
|
EBV Target gene Detail Information
