Gene Name	ARHGAP42
Gene ID	143872
Gene Full Name	Rho GTPase activating protein 42
Gene Alias	AD031|GRAF3|TMEM133
Transcripts	ENSG00000165895
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Nuclear speckles;Cytosol;
Membrane Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	A6NI28
HGNC ID	HGNC:26545
OMIM ID	615936
Summary	This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5002004	chr11	15	2	0	17	View
5003047	chr11	0	1	5	6	View
5003419	chr11	2	1	0	3	View
5003607	chr11	0	0	2	2	View
5004189	chr11	1	0	0	1	View
5006940	chr11	2	13	3	18	View
5014809	chr11	124	3	1	128	View
5014810	chr11	2	1	5	8	View
5014811	chr11	16	5	0	21	View
5014812	chr11	27	30	0	57	View
5014813	chr11	2	0	0	2	View

Data ID	Experiment type	Sample number	Platform
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE40774	Expression array	134	Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE164690	scRNA-seq	51	Illumina NextSeq 500 (Homo sapiens)
GSE197461	scRNA-seq	16	Illumina NovaSeq 6000 (Homo sapiens)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE183048 - ARHGAP42 peak across samples

Peak Plot

> Dataset: GSE143026 - ARHGAP42 peak across samples

Peak Plot