Gene Information
|
Gene Name
|
COL6A1 |
|
Gene ID
|
1291
|
|
Gene Full Name
|
collagen type VI alpha 1 chain |
|
Gene Alias
|
BTHLM1|BTHLM1A|OPLL|UCHMD1|UCHMD1A |
|
Transcripts
|
ENSG00000142156
|
|
Virus
|
SARS-CoV-2 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol;Secreted to extracellular matrix; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
|
Uniport_ID
|
P12109
|
|
HGNC ID
|
HGNC:2211
|
|
OMIM ID
|
120220 |
|
Summary
|
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008] |
Target gene [COL6A1] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [COL6A1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
E GSE167075
|
MeRIP-seq;RNA-seq |
16 |
Illumina NovaSeq 6000 (Homo sapiens; Severe acute respiratory syndrome coronavirus 2);Illumina NovaSeq 6000 (Chlorocebus aethiops; Severe acute respiratory syndrome coronavirus 2) |
|
GSE164485
|
scRNA-seq |
36 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE190680
|
RNA-seq |
100 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE207923
|
RNA-seq |
27 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE152641
|
RNA-seq |
86 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE283771
|
RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
GSE211934
|
RNA-seq |
8 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE163959
|
RNA-seq |
48 |
Illumina NextSeq 500 (Homo sapiens) |
|
S GSE206147
|
scRNA-seq |
1 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE166253
|
RNA-seq |
26 |
HiSeq X Ten (Homo sapiens) |
|
GSE153218
|
RNA-seq |
16 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE162323
|
RNA-seq |
42 |
Illumina NovaSeq 6000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens; Severe acute respiratory syndrome coronavirus 2) |
|
GSE199816
|
RNA-seq |
27 |
DNBSEQ-G400 (Homo sapiens) |
|
GSE215262
|
RNA-seq |
25 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE167075 - COL6A1 expression across samples
|
Volcano Plot
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Bar Plot
|
|
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SARS-CoV-2 Target gene Detail Information
