Gene Name	GIGYF2
Gene ID	26058
Gene Full Name	GRB10 interacting GYF protein 2
Gene Alias	GYF2|PARK11|PERQ2|PERQ3|TNRC15
Transcripts	ENSG00000204120
Virus	SARS-CoV-2
Gene Type	protein-coding
HPA Location Info	Cytosol;
Membrane Info	Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID	Q6Y7W6
HGNC ID	HGNC:11960
OMIM ID	612003
Summary	This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	38365933	A929G	ORF1ab	ORF1ab	COVID-19 Cell line	G R T	View
2	38365933	I222V	ORF1ab	ORF1ab	COVID-19 Cell line	G R T	View

Data ID	Experiment type	Sample number	Platform
GSE167075	MeRIP-seq;RNA-seq	16	Illumina NovaSeq 6000 (Homo sapiens; Severe acute respiratory syndrome coronavirus 2);Illumina NovaSeq 6000 (Chlorocebus aethiops; Severe acute respiratory syndrome coronavirus 2)
GSE164485	scRNA-seq	36	Illumina HiSeq 2500 (Homo sapiens)
GSE190680	RNA-seq	100	Illumina NovaSeq 6000 (Homo sapiens)
GSE207923	RNA-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE152641	RNA-seq	86	Illumina NovaSeq 6000 (Homo sapiens)
GSE283771	RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
GSE211934	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE163959	RNA-seq	48	Illumina NextSeq 500 (Homo sapiens)
C   GSE163623	Chip-seq	5	Illumina NovaSeq 6000 (Homo sapiens)
GSE166253	RNA-seq	26	HiSeq X Ten (Homo sapiens)
GSE153218	RNA-seq	16	Illumina NextSeq 500 (Homo sapiens)
GSE162323	RNA-seq	42	Illumina NovaSeq 6000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens; Severe acute respiratory syndrome coronavirus 2)
GSE199816	RNA-seq	27	DNBSEQ-G400 (Homo sapiens)
E   GSE215262	RNA-seq	25	Illumina NovaSeq 6000 (Homo sapiens)

• Expression profiling
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE215262 - GIGYF2 expression across samples

Volcano Plot

Bar Plot