HPV Target gene Detail Information

> IGFBP6 Gene Search Result


Gene Information
Gene Name IGFBP6
Gene ID 3489
Gene Full Name insulin like growth factor binding protein 6
Gene Alias IBP6
Transcripts ENSG00000167779
Virus HPV
Gene Type protein-coding
HPA Location Info Secreted to blood;
Membrane Info Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P24592
HGNC ID HGNC:5475
OMIM ID 146735
Summary Enables identical protein binding activity and insulin-like growth factor II binding activity. Involved in cell migration and positive regulation of stress-activated MAPK cascade. Part of insulin-like growth factor binary complex. Implicated in obesity. Biomarker of breast cancer; in situ carcinoma; leiomyoma; and neovascular inflammatory vitreoretinopathy. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [IGFBP6] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5012606 chr12 1405 597 302 2304 View
5012607 chr12 44 4 0 48 View
5012608 chr12 44 4 0 48 View
5012609 chr12 55 5 0 60 View
5012610 chr12 56 5 0 61 View
5012611 chr12 59 5 0 64 View
5012612 chr12 55 3 0 58 View
5012613 chr12 55 3 0 58 View

Target gene [IGFBP6] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048 		Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
S
  GSE226620 		scRNA-seq 30 HiSeq X Ten (Homo sapiens)
GSE40774 Expression array 134 Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
M
  GSE169622 		Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
S
  GSE164690 		scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
E
  GSE55542 		Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
S
  GSE197461 		scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE55542 - IGFBP6 expression across samples

Volcano Plot

Bar Plot