HPV Target gene Detail Information

> IRF4 Gene Search Result


Gene Information
Gene Name IRF4
Gene ID 3662
Gene Full Name interferon regulatory factor 4
Gene Alias IMD131|LSIRF|MUM1|NF-EM5|SHEP8
Transcripts ENSG00000137265
Virus HPV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Cytosol;
Membrane Info Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q15306
HGNC ID HGNC:6119
OMIM ID 601900
Summary The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
Target gene [IRF4] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5010035 chr6 135 98 92 325 View
5010043 chr6 109 89 90 288 View
5010044 chr6 136 99 90 325 View
5016069 chr6 601 361 290 1252 View
5016070 chr6 1550 463 254 2267 View
5016071 chr6 221 1 0 222 View
5016072 chr6 59 10 4 73 View
5016073 chr6 54 41 3 98 View
5016074 chr6 24 8 0 32 View
5016075 chr6 8 2 0 10 View
5016076 chr6 85 68 8 161 View
5016077 chr6 28 2 0 30 View
5016078 chr6 176 34 22 232 View
5016079 chr6 439 57 68 564 View
5016080 chr6 405 60 62 527 View
5016081 chr6 114 4 0 118 View
5016082 chr6 14 1 0 15 View
5016083 chr6 1 0 0 1 View
5016084 chr6 3 0 1 4 View
5016085 chr6 4 2 0 6 View
5016086 chr6 210 59 57 326 View
5016087 chr6 229 210 239 678 View
5016088 chr6 288 770 631 1689 View
5016089 chr6 49 114 6 169 View
5016090 chr6 26 60 1 87 View

Target gene [IRF4] related to Omics data
Data ID Experiment type Sample number Platform
S
  GSE226620 		scRNA-seq 30 HiSeq X Ten (Homo sapiens)
S
  GSE139324 		scRNA-seq 63 Illumina NextSeq 500 (Homo sapiens)
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
S
  GSE164690 		scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE197461 scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
E
  TCGA_CESC 		DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE199029 Variation;RNA-seq 44 NanoString Human nCounter PanCancer IO360 Panel
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: TCGA_CESC - IRF4 expression across samples

Volcano Plot

Bar Plot