HPV Target gene Detail Information

> KLF5 Gene Search Result


Gene Information
Gene Name KLF5
Gene ID 688
Gene Full Name KLF transcription factor 5
Gene Alias BTEB2|CKLF|IKLF
Transcripts ENSG00000102554
Virus HPV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Golgi apparatus, Vesicles;
Membrane Info Cancer-related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q13887
HGNC ID HGNC:6349
OMIM ID 602903
Summary This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Target gene [KLF5] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5001558 chr13 9 15 5 29 View
5002301 chr13 12 1 0 13 View
5002407 chr13 10 1 1 12 View
5002496 chr13 7 4 0 11 View
5004720 chr13 2885 3286 1183 7354 View
5007624 chr13 12 0 0 12 View
5009923 chr13 1 1 0 2 View
5010170 chr13 7 0 0 7 View
5012030 chr13 7 4 0 11 View
5012064 chr13 5 25 2 32 View
5012123 chr13 5 12 1 18 View
5012126 chr13 5 26 2 33 View
5012127 chr13 5 13 1 19 View
5012128 chr13 5 12 1 18 View
5014964 chr13 71 1 0 72 View
5014965 chr13 2095 1917 1607 5619 View
5014966 chr13 25 2 1 28 View
5014967 chr13 33 5 7 45 View
5017128 chr13 21 0 0 21 View
5017129 chr13 15 1 0 16 View
5017130 chr13 13 3 0 16 View
5017131 chr13 2 1 0 3 View
5017132 chr13 17 3 2 22 View
5017133 chr13 13 2 0 15 View
5017134 chr13 5 4 0 9 View
5017135 chr13 8 326 91 425 View
5017136 chr13 10 3 4 17 View
5017137 chr13 8 33 2 43 View

Target gene [KLF5] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048 		Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE40774 Expression array 134 Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
S
  GSE164690 		scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
E
  TCGA_CESC 		DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
S
  GSE197461 		scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: TCGA_CESC - KLF5 expression across samples

Volcano Plot

Bar Plot