Gene Information
|
Gene Name
|
PARP1 |
|
Gene ID
|
142
|
|
Gene Full Name
|
poly(ADP-ribose) polymerase 1 |
|
Gene Alias
|
ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PARS|PPOL|Poly-PARP|pADPRT-1 |
|
Transcripts
|
ENSG00000143799
|
|
Virus
|
KSHV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Nucleoli; 
|
|
Membrane Info
|
Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
P09874
|
|
HGNC ID
|
HGNC:270
|
|
OMIM ID
|
173870 |
|
Summary
|
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008] |
Target gene [PARP1] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [PARP1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE232843
|
RNA-seq |
12 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE79029
|
RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
C GSE202670
|
Chip-seq |
14 |
Illumina Genome Analyzer (Homo sapiens) |
|
GSE280380
|
RNA-seq |
54 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE158935
|
RNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE132777
|
Chip-seq |
10 |
Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
|
C GSE147063
|
Chip-seq;GRO-seq;4C-seq |
10 |
Illumina NextSeq 500 (Homo sapiens);Illumina Hiseq 2500 (Homo sapiens) |
|
GSE207589
|
RNA-seq |
12 |
Illumina HiSeq 2000 (Homo sapiens) |
|
GSE241095
|
RNA-seq |
44 |
Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE135740
|
Chip-seq |
10 |
Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
|
C GSE52421
|
Chip-seq |
18 |
Illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE280006
|
RNA-seq |
14 |
NextSeq 550 (Homo sapiens) |
|
C GSE38411
|
Chip-seq |
5 |
Illumina Genome Analyzer II (Homo sapiens);Illumina Genome Analyzer II (Human herpesvirus 8) |
|
GSE260925
|
RNA-seq |
24 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE56144
|
Chip-seq;RNA-seq |
33 |
Illumina Genome Analyzer II (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE202670 - PARP1 peak across samples
|
Peak Plot
|
> Dataset: GSE132777 - PARP1 peak across samples
|
Peak Plot
|
> Dataset: GSE147063 - PARP1 peak across samples
|
Peak Plot
|
> Dataset: GSE135740 - PARP1 peak across samples
|
Peak Plot
|
> Dataset: GSE52421 - PARP1 peak across samples
|
Peak Plot
|
> Dataset: GSE38411 - PARP1 peak across samples
|
Peak Plot
|
> Dataset: GSE56144 - PARP1 peak across samples
|
Peak Plot
|
|
|
KSHV Target gene Detail Information
