HPV Target gene Detail Information

> PDE4D Gene Search Result


Gene Information
Gene Name PDE4D
Gene ID 5144
Gene Full Name phosphodiesterase 4D
Gene Alias ACRDYS2|DPDE3|HSPDE4D|PDE43|PDE4DN2|STRK1
Transcripts ENSG00000113448
Virus HPV
Gene Type protein-coding
HPA Location Info Plasma membrane, Cytosol;Nucleoplasm, Nuclear membrane, Primary cilium;
Membrane Info Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID Q08499
HGNC ID HGNC:8783
OMIM ID 600129
Summary This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
Target gene [PDE4D] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5001746 chr5 17 7 0 24 View
5002681 chr5 7 2 0 9 View
5002682 chr5 7 2 0 9 View
5003272 chr5 3 1 0 4 View
5003447 chr5 2 1 0 3 View
5003476 chr5 1 2 0 3 View
5004253 chr5 0 1 0 1 View
5005993 chr5 2 0 6 8 View
5006557 chr5 13 9 0 22 View
5007155 chr5 17 3 8 28 View
5007630 chr5 0 0 0 0 View
5007674 chr5 19 8 3 30 View
5007686 chr5 0 1 0 1 View
5007687 chr5 0 1 0 1 View
5007688 chr5 0 0 0 0 View
5007689 chr5 1 0 0 1 View
5007690 chr5 3 1 0 4 View
5007691 chr5 2 0 0 2 View
5007692 chr5 1 4 11 16 View
5010552 chr5 1 1 0 2 View
5010631 chr5 0 0 4 4 View
5011644 chr5 3 2 0 5 View
5013599 chr5 0 11 2 13 View
5013600 chr5 51 18 19 88 View
5013601 chr5 456 95 43 594 View
5013602 chr5 11 2 18 31 View
5016001 chr5 1 0 0 1 View
5016002 chr5 0 1 1 2 View
5016003 chr5 7 0 0 7 View
5016004 chr5 1 0 0 1 View
5016005 chr5 0 0 0 0 View
5016006 chr5 0 1 0 1 View
5016007 chr5 2 0 0 2 View
5016008 chr5 7 5 11 23 View

Target gene [PDE4D] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048
Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE226620 scRNA-seq 30 HiSeq X Ten (Homo sapiens)
GSE40774 Expression array 134 Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE139324 scRNA-seq 63 Illumina NextSeq 500 (Homo sapiens)
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE164690 scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C
  GSE143026
ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE197461 scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE183048 - PDE4D peak across samples

Peak Plot


> Dataset: GSE143026 - PDE4D peak across samples

Peak Plot