KSHV Target gene Detail Information

> RBPJ Gene Search Result


Gene Information
Gene Name RBPJ
Gene ID 3516
Gene Full Name recombination signal binding protein for immunoglobulin kappa J region
Gene Alias AOS3|CBF-1|CBF1|IGKJRB|IGKJRB1|KBF2|RBP-J|RBP-J kappa|RBP-JK|RBPJK|RBPSUH|SUH|csl
Transcripts ENSG00000168214
Virus KSHV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q06330
HGNC ID HGNC:5724
OMIM ID 147183
Summary The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]
Target gene [RBPJ] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 17850910 K152E
RTA
ORF50
Cell line
T
 View

Target gene [RBPJ] related to Omics data
Data ID Experiment type Sample number Platform
GSE232843 RNA-seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE79029 RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE202670 		Chip-seq 14 Illumina Genome Analyzer (Homo sapiens)
GSE280380 RNA-seq 54 Illumina NovaSeq 6000 (Homo sapiens)
GSE158935 RNA-seq 6 Illumina HiSeq 2500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE132777 		Chip-seq 10 Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE147063 Chip-seq;GRO-seq;4C-seq 10 Illumina NextSeq 500 (Homo sapiens);Illumina Hiseq 2500 (Homo sapiens)
GSE207589 RNA-seq 12 Illumina HiSeq 2000 (Homo sapiens)
GSE241095 RNA-seq 44 Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE135740 		Chip-seq 10 Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
C
  GSE52421 		Chip-seq 18 Illumina Genome Analyzer IIx (Homo sapiens)
GSE280006 RNA-seq 14 NextSeq 550 (Homo sapiens)
C
  GSE38411 		Chip-seq 5 Illumina Genome Analyzer II (Homo sapiens);Illumina Genome Analyzer II (Human herpesvirus 8)
GSE260925 RNA-seq 24 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE56144 		Chip-seq;RNA-seq 33 Illumina Genome Analyzer II (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE202670 - RBPJ peak across samples

Peak Plot

> Dataset: GSE132777 - RBPJ peak across samples

Peak Plot

> Dataset: GSE135740 - RBPJ peak across samples

Peak Plot

> Dataset: GSE52421 - RBPJ peak across samples

Peak Plot

> Dataset: GSE38411 - RBPJ peak across samples

Peak Plot

> Dataset: GSE56144 - RBPJ peak across samples

Peak Plot