Gene Information
|
Gene Name
|
RIGI |
|
Gene ID
|
23586
|
|
Gene Full Name
|
RNA sensor RIG-I |
|
Gene Alias
|
DDX58|RIG-I|RIG1|RLR-1|SGMRT2 |
|
Transcripts
|
ENSG00000107201
|
|
Virus
|
EBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane, Cytosol; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
O95786
|
|
HGNC ID
|
HGNC:19102
|
|
OMIM ID
|
609631 |
|
Summary
|
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. [provided by RefSeq, Aug 2020] |
Target gene [RIGI] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 3000269 |
chr9 |
11 |
33 |
2 |
46 |
View |
Target gene [RIGI] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE42867
|
Expression array |
12 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
C GSE246060
|
Chip-seq |
26 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE198334
|
Chip-seq |
4 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE100458
|
Expression array |
14 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array [CDF: Brainarray HGU133Plus2_Hs_ENTREZG_v21] |
|
GSE165194
|
RNA-seq |
3 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE246059
|
ATAC-seq |
8 |
Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE225248
|
Chip-seq |
12 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE102203
|
Expression array |
10 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [probe set (exon) version] |
|
GSE85599
|
Expression array |
17 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
GSE181906
|
RNA-seq |
24 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE246060 - RIGI peak across samples
|
Peak Plot
|
> Dataset: GSE198334 - RIGI peak across samples
|
Peak Plot
|
> Dataset: GSE246059 - RIGI peak across samples
|
Peak Plot
|
> Dataset: GSE225248 - RIGI peak across samples
|
Peak Plot
|
|
|
EBV Target gene Detail Information
