Gene Name	WASF2
Gene ID	10163
Gene Full Name	WASP family member 2
Gene Alias	IMD2|SCAR2|WASF4|WAVE2|dJ393P12.2
Transcripts	ENSG00000158195
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Plasma membrane;Cytosol;
Membrane Info	Predicted intracellular proteins
Uniport_ID	Q9Y6W5
HGNC ID	HGNC:12733
OMIM ID	605875
Summary	This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5007836	chr1	18	5	18	41	View
5012312	chr1	63	8	25	96	View
5012313	chr1	36	5	0	41	View
5012314	chr1	2	2	0	4	View
5012315	chr1	25	20	1	46	View
5012316	chr1	570	114	168	852	View
5012317	chr1	568	113	167	848	View
5012318	chr1	211	13	15	239	View
5012319	chr1	4381	1970	667	7018	View
5014539	chr1	44	2	0	46	View
5014540	chr1	13	3	0	16	View
5014541	chr1	191	46	12	249	View
5014542	chr1	521	55	1	577	View
5014543	chr1	507	53	1	561	View

Data ID	Experiment type	Sample number	Platform
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE226620	scRNA-seq	30	HiSeq X Ten (Homo sapiens)
GSE40774	Expression array	134	Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE139324	scRNA-seq	63	Illumina NextSeq 500 (Homo sapiens)
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE164690	scRNA-seq	51	Illumina NextSeq 500 (Homo sapiens)
GSE138080	Expression array	35	Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE197461	scRNA-seq	16	Illumina NovaSeq 6000 (Homo sapiens)
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE183048 - WASF2 peak across samples

Peak Plot

> Dataset: GSE143026 - WASF2 peak across samples

Peak Plot