All Curated Mutation Sites in HIV 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HIV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
*Please select one option you are interested in, the page will be automatically redirected.
     
     

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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Keyword: Env
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 17634131 D36E
Env
Env
HIV Infections
G
S
L
View
2 17634131 D36L
Env
Env
HIV Infections
G
S
L
View
3 18177204 I675V
Env
Env
HIV Infections
G
R
L
View
4 18177204 T569A
Env
Env
HIV Infections
G
R
L
View
5 40034260 T8V
Env
Env
HIV Infections
D
G
S
L
View
6 30538178 K305A
Env
Env
Acquired Immunodeficiency Syndrome
G
R
I
L
View
7 30302011 N301A
Env
Env

D
G
R
I
View
8 30538178 R304A
Env
Env
Acquired Immunodeficiency Syndrome
G
R
I
L
View
9 30538178 Y173A
Env
Env
Acquired Immunodeficiency Syndrome
G
R
I
L
View
10 30538178 Y173F
Env
Env
Acquired Immunodeficiency Syndrome
G
R
I
L
View
11 30538178 Y177A
Env
Env
Acquired Immunodeficiency Syndrome
G
R
I
L
View
12 30538178 Y177F
Env
Env
Acquired Immunodeficiency Syndrome
G
R
I
L
View
13 18673537 I318T
Env
Env
HIV Infections
G
R
View
14 18673537 N297K
Env
Env
HIV Infections
G
R
View
15 18673537 N298Y
Env
Env
HIV Infections
G
R
View
16 20494390 I309L
Env
Env
HIV Infections
G
S
I
View
17 33883222 G308E
Env
Env
Acquired Immunodeficiency Syndrome
D
G
C
View
18 33883222 G308V
Env
Env
Acquired Immunodeficiency Syndrome
D
G
C
View
19 33883222 G310E
Env
Env
Acquired Immunodeficiency Syndrome
D
G
C
View
20 33883222 G310K
Env
Env
Acquired Immunodeficiency Syndrome
D
G
C
View
21 33883222 G310L
Env
Env
Acquired Immunodeficiency Syndrome
D
G
C
View
22 29222332 A316W
Env
Env
HIV Infections
G
R
View
23 29222332 A561C
Env
Env
HIV Infections
G
R
View
24 29222332 A73C
Env
Env
HIV Infections
G
R
View
25 29222332 E64K
Env
Env
HIV Infections
G
R
View
26 29222332 S306L/A316W
Env
Env
HIV Infections
G
R
View
27 29222332 S306L/R308L
Env
Env
HIV Infections
G
R
View
28 29222332 S306L/R308L/A316W
Env
Env
HIV Infections
G
R
View
29 29672607 A319T
Env
Env
HIV Infections
G
S
I
C
L
View
30 29672607 D322R
Env
Env
HIV Infections
G
S
I
C
L
View
31 29672607 F317L
Env
Env
HIV Infections
G
S
I
C
L
View
32 29672607 H308T
Env
Env
HIV Infections
G
S
I
C
L
View
33 29672607 I307T
Env
Env
HIV Infections
G
S
I
C
L
View
34 29672607 R315Q
Env
Env
HIV Infections
G
S
I
C
L
View
35 29769530 N160D
Env
Env
HIV Infections
G
L
View
36 29769530 N160K
Env
Env
HIV Infections
G
L
View
37 29769530 N160S
Env
Env
HIV Infections
G
L
View
38 29769530 N295E
Env
Env
HIV Infections
G
L
View
39 29769530 N295I
Env
Env
HIV Infections
G
L
View
40 29769530 N295K
Env
Env
HIV Infections
G
L
View
41 29769530 N295S
Env
Env
HIV Infections
G
L
View
42 17087820 G89A
Env
Env
Cell line
G
R
T
View
43 17087820 G89V
Env
Env
Cell line
G
R
T
View
44 17134507 A221V
Env
Env
Cell line
G
R
I
T
View
45 17134507 G431A
Env
Env
Cell line
G
R
I
T
View
46 17134507 G431E
Env
Env
Cell line
G
R
I
T
View
47 17134507 G431R
Env
Env
Cell line
D
G
R
I
T
View
48 17134507 N750N
Env
Env
Cell line
G
R
I
T
View
49 17134507 N750T
Env
Env
Cell line
G
R
I
T
View
50 17134507 Q567R
Env
Env
Cell line
G
R
I
T
View
51 29950423 K169E
Env
Env
HIV Infections
G
I
C
L
View
52 29950423 N160A
Env
Env
HIV Infections
G
I
C
L
View
53 29950423 N160K
Env
Env
HIV Infections
G
I
C
L
View
54 29950423 N234A
Env
Env
HIV Infections
G
I
C
L
View
55 29950423 N276A
Env
Env
HIV Infections
G
I
C
L
View
56 29950423 N279A
Env
Env
HIV Infections
G
I
C
L
View
57 17134507 Q799H
Env
Env
Cell line
G
R
I
T
View
58 29950423 N332A
Env
Env
HIV Infections
G
I
C
L
View
59 29950423 N611D
Env
Env
HIV Infections
G
I
C
L
View
60 29950423 N637A
Env
Env
HIV Infections
G
I
C
L
View
61 29950423 N88A
Env
Env
HIV Infections
G
I
C
L
View
62 29950423 P363N
Env
Env
HIV Infections
G
I
C
L
View
63 29950423 R456W
Env
Env
HIV Infections
G
I
C
L
View
64 17134507 Q799Q
Env
Env
Cell line
G
R
I
T
View
65 17134507 Y762C
Env
Env
Cell line
G
R
I
T
View
66 17134507 Y762Y
Env
Env
Cell line
G
R
I
T
View
67 18237398 A316T
Env
Env
Cell line
G
R
View
68 18237398 A433T
Env
Env
Cell line
G
R
View
69 18237398 A436T
Env
Env
Cell line
G
R
View
70 18237398 C418A
Env
Env
Cell line
G
R
View
71 18237398 N230D
Env
Env
Cell line
G
R
View
72 18237398 N339Y
Env
Env
Cell line
G
R
View
73 18237398 N386D
Env
Env
Cell line
G
R
I
View
74 18237398 R696K
Env
Env
Cell line
G
R
View
75 18237398 T188N
Env
Env
Cell line
G
R
View
76 18837996 N283T
Env
Env
Cell line
G
View
77 18837996 T283N
Env
Env
Cell line
G
View
78 30650070 T332N
Env
Env
HIV Infections
G
View
79 23011758 D474A
Env
Env
Cell line
D
G
View
80 23011758 E102A
Env
Env
Cell line
G
View
81 23011758 E370A
Env
Env
Cell line
G
View
82 23011758 I371A
Env
Env
Cell line
G
View
83 23011758 K120A
Env
Env
Cell line
G
View
84 23011758 K421A
Env
Env
Cell line
G
View
85 23011758 K97A
Env
Env
Cell line
G
View
86 23011758 L122A
Env
Env
Cell line
G
View
87 23011758 M426A
Env
Env
Cell line
G
View
88 23011758 M475A
Env
Env
Cell line
G
View
89 23011758 M95A
Env
Env
Cell line
G
View
90 23011758 N98A
Env
Env
Cell line
G
View
91 23011758 N99A
Env
Env
Cell line
G
View
92 23011758 R476A
Env
Env
Cell line
G
View
93 23011758 R480A
Env
Env
Cell line
G
View
94 23011758 T257A
Env
Env
Cell line
D
G
View
95 23011758 V101A
Env
Env
Cell line
G
View
96 31010245 R189S
Env
Env
HIV Infections
G
R
S
L
View
97 23011758 V121A
Env
Env
Cell line
G
View
98 23011758 V255A
Env
Env
Cell line
G
View
99 23011758 V372A
Env
Env
Cell line
G
View
100 23011758 V430A
Env
Env
Cell line
G
View
101 31178836 E279K
Env
Env
HIV Infections
G
R
I
L
View
102 31178836 K282R
Env
Env
HIV Infections
G
R
I
L
View
103 31178836 N462T
Env
Env
HIV Infections
G
R
I
L
View
104 24758333 460insD
Env
Env
Cell line
G
R
S
View
105 24758333 D185E
Env
Env
Cell line
G
R
S
View
106 24758333 D185G
Env
Env
Cell line
G
R
S
View
107 24758333 D185N
Env
Env
Cell line
G
R
S
View
108 24758333 delNIND
Env
Env
Cell line
G
R
S
View
109 24758333 E185D
Env
Env
Cell line
G
R
S
View
110 24758333 G185D
Env
Env
Cell line
G
R
S
View
111 24758333 H144L
Env
Env
Cell line
G
R
S
View
112 24758333 I190T
Env
Env
Cell line
G
R
S
View
113 24758333 N185D
Env
Env
Cell line
G
R
S
View
114 24758333 N186Q
Env
Env
Cell line
G
R
S
View
115 24758333 N189S
Env
Env
Cell line
G
R
S
View
116 24758333 N197Q
Env
Env
Cell line
G
R
S
View
117 24758333 N301Q
Env
Env
Cell line
G
R
S
View
118 24758333 N339Q
Env
Env
Cell line
G
R
S
View
119 24758333 N386Q
Env
Env
Cell line
G
R
S
View
120 24758333 N392Q
Env
Env
Cell line
G
R
S
View
121 24758333 R500M
Env
Env
Cell line
G
R
S
View
122 24758333 V488I
Env
Env
Cell line
G
R
S
View
123 24884783 T332N
Env
Env
Cell line
G
View
124 31640718 A48T
Env
Env
HIV Infections
D
G
S
View
125 31640718 A612T
Env
Env
HIV Infections
D
G
S
View
126 31640718 A823V
Env
Env
HIV Infections
D
G
S
View
127 31640718 E83K
Env
Env
HIV Infections
D
G
S
View
128 31640718 F175L
Env
Env
HIV Infections
D
G
S
View
129 31640718 G464E
Env
Env
HIV Infections
D
G
S
View
130 31640718 H643Y
Env
Env
HIV Infections
D
G
S
View
131 31640718 N136D
Env
Env
HIV Infections
D
G
S
View
132 31640718 N136K
Env
Env
HIV Infections
D
G
S
View
133 31640718 N301K
Env
Env
HIV Infections
D
G
S
View
134 31640718 N460I
Env
Env
HIV Infections
D
G
S
View
135 31640718 N674T
Env
Env
HIV Infections
D
G
S
View
136 31640718 Q550H
Env
Env
HIV Infections
D
G
S
View
137 31640718 Q577K
Env
Env
HIV Infections
D
G
S
View
138 31640718 Q577N
Env
Env
HIV Infections
D
G
S
View
139 31640718 Q577R
Env
Env
HIV Infections
D
G
R
S
View
140 31640718 R146K
Env
Env
HIV Infections
D
G
S
View
141 31640718 S306R
Env
Env
HIV Infections
D
G
S
View
142 31640718 S465P
Env
Env
HIV Infections
D
G
S
View
143 31640718 T19I
Env
Env
HIV Infections
D
G
S
View
144 31640718 T319A
Env
Env
HIV Infections
D
G
S
View
145 31640718 V200E
Env
Env
HIV Infections
D
G
S
View
146 31640718 V255A
Env
Env
HIV Infections
D
G
S
View
147 31640718 V583V
Env
Env
HIV Infections
D
G
S
View
148 31640718 V693I
Env
Env
HIV Infections
D
G
S
View
149 31683782 D62E
Env
Env
HIV Infections
G
R
S
L
View
150 31683782 D751V
Env
Env
HIV Infections
G
R
S
L
View
151 31683782 F717F
Env
Env
HIV Infections
G
R
S
L
View
152 31683782 F717L
Env
Env
HIV Infections
G
R
S
L
View
153 31683782 G514T
Env
Env
HIV Infections
G
R
S
L
View
154 31683782 I154M
Env
Env
HIV Infections
G
R
S
L
View
155 31683782 I360V
Env
Env
HIV Infections
G
R
S
L
View
156 31683782 K33Q
Env
Env
HIV Infections
G
R
S
L
View
157 31683782 L464N
Env
Env
HIV Infections
G
R
S
L
View
158 31683782 M24I
Env
Env
HIV Infections
G
R
S
L
View
159 31683782 Q621D
Env
Env
HIV Infections
G
R
S
L
View
160 31683782 R737T
Env
Env
HIV Infections
G
R
S
L
View
161 31683782 R744R
Env
Env
HIV Infections
G
R
S
L
View
162 31683782 R744T
Env
Env
HIV Infections
G
R
S
L
View
163 31683782 R747R
Env
Env
HIV Infections
G
R
S
L
View
164 31683782 R841I
Env
Env
HIV Infections
G
R
S
L
View
165 31683782 R841L
Env
Env
HIV Infections
G
R
S
L
View
166 27754450 N659D
Env
Env
Cell line
G
R
View
167 28100611 C6795T
Env
Env
Cell line
G
View
168 28100611 T192M
Env
Env
Cell line
G
View
169 28100611 T192R
Env
Env
Cell line
G
View
170 30566493 A219V
Env
Env
Cell line
G
S
View
171 30566493 A433T
Env
Env
Cell line
G
S
View
172 30566493 C131Y
Env
Env
Cell line
G
S
View
173 30566493 D138G
Env
Env
Cell line
G
S
View
174 30566493 D138Y
Env
Env
Cell line
G
S
View
175 30566493 E466V
Env
Env
Cell line
G
S
View
176 30566493 E87G
Env
Env
Cell line
G
S
View
177 30566493 F159Y
Env
Env
Cell line
G
S
View
178 30566493 G472E
Env
Env
Cell line
G
S
View
179 30566493 I213F
Env
Env
Cell line
G
S
View
180 30566493 K510N
Env
Env
Cell line
G
S
View
181 30566493 K574M
Env
Env
Cell line
G
S
View
182 30566493 L555P
Env
Env
Cell line
G
S
View
183 30566493 M165L
Env
Env
Cell line
G
S
View
184 30566493 N137D
Env
Env
Cell line
G
S
View
185 30566493 N160Y
Env
Env
Cell line
G
S
View
186 30566493 N187D
Env
Env
Cell line
G
S
View
187 30566493 N88D
Env
Env
Cell line
G
S
View
188 30566493 Q172H
Env
Env
Cell line
G
S
View
189 30566493 Q464E
Env
Env
Cell line
G
S
View
190 30566493 Q590P
Env
Env
Cell line
G
S
View
191 30566493 R500T
Env
Env
Cell line
G
S
View
192 30566493 R503W
Env
Env
Cell line
G
S
View
193 30566493 S195C
Env
Env
Cell line
G
S
View
194 30566493 S440G
Env
Env
Cell line
G
S
View
195 30566493 S534T
Env
Env
Cell line
G
S
View
196 30566493 S618T
Env
Env
Cell line
G
S
View
197 30566493 T132N
Env
Env
Cell line
G
S
View
198 30566493 T141S
Env
Env
Cell line
G
S
View
199 30566493 T569I
Env
Env
Cell line
G
S
View
200 30566493 V539I
Env
Env
Cell line
G
S
View
201 30566493 V89L
Env
Env
Cell line
G
S
View
202 30566493 Y217F
Env
Env
Cell line
G
S
View
203 30566493 Y643N
Env
Env
Cell line
G
S
View
204 30709739 D113N
Env
Env
Cell line
G
R
I
View
205 30709739 D325E
Env
Env
Cell line
G
R
I
View
206 30709739 D325S
Env
Env
Cell line
G
R
I
View
207 30709739 H330R
Env
Env
Cell line
G
R
I
View
208 30709739 I326Y
Env
Env
Cell line
G
R
I
View
209 30709739 L369K
Env
Env
Cell line
G
R
I
View
210 30709739 N197E
Env
Env
Cell line
G
R
I
View
211 30709739 N197S
Env
Env
Cell line
G
R
I
View
212 30709739 N197T
Env
Env
Cell line
G
R
I
View
213 30709739 T332N
Env
Env
Cell line
G
R
I
View
214 30769947 R722G
Env
Env
Cell line
G
View
215 30769947 S727P
Env
Env
Cell line
G
View
216 30769947 Y712I
Env
Env
Cell line
G
View
217 30808702 A583T
Env
Env
Cell line
G
R
S
View
218 30808702 E434K
Env
Env
Cell line
G
R
S
View
219 30808702 I520M
Env
Env
Cell line
G
R
S
View
220 30808702 K660E
Env
Env
Cell line
G
R
S
View
221 30808702 N306K
Env
Env
Cell line
G
R
S
View
222 32156815 A319K
Env
Env
HIV Infections
G
C
L
View
223 32156815 A319T
Env
Env
HIV Infections
G
C
L
View
224 32156815 D322A
Env
Env
HIV Infections
G
C
L
View
225 32156815 D322R
Env
Env
HIV Infections
G
C
L
View
226 32156815 F317A
Env
Env
HIV Infections
G
C
L
View
227 32156815 F317L
Env
Env
HIV Infections
G
C
L
View
228 30808702 Q555H
Env
Env
Cell line
G
R
S
View
229 32156815 H308T
Env
Env
HIV Infections
G
C
L
View
230 32156815 I307T
Env
Env
HIV Infections
G
C
L
View
231 32156815 N160A
Env
Env
HIV Infections
G
C
L
View
232 32156815 N160K
Env
Env
HIV Infections
G
R
C
L
View
233 32156815 N276Q
Env
Env
HIV Infections
D
G
R
C
L
View
234 32156815 N279A
Env
Env
HIV Infections
G
R
C
L
View
235 32156815 N332A
Env
Env
HIV Infections
G
R
C
L
View
236 32156815 T334A
Env
Env
HIV Infections
G
C
L
View
237 30808702 R538A
Env
Env
Cell line
G
R
S
View
238 30814513 K160N
Env
Env
Cell line
G
R
View
239 31266880 D167H
Env
Env
Cell line
D
G
R
View
240 32669335 L184F
Env
Env
HIV Infections
D
G
R
I
L
View
241 31266880 G6719C
Env
Env
Cell line
D
G
R
View
242 31527908 E64K
Env
Env
Cell line
G
View
243 31527908 G458C
Env
Env
Cell line
G
View
244 31527908 G458L
Env
Env
Cell line
G
View
245 31527908 K19T
Env
Env
Cell line
G
View
246 31527908 N279K
Env
Env
Cell line
G
View
247 31527908 N280D
Env
Env
Cell line
G
View
248 31527908 N461A
Env
Env
Cell line
G
View
249 31527908 N462A
Env
Env
Cell line
G
View
250 31527908 S365P
Env
Env
Cell line
D
G
View
251 31527908 T463A
Env
Env
Cell line
G
View
252 32879304 F673L
Env
Env
HIV Infections
D
G
R
S
L
View
253 32879304 G514W
Env
Env
HIV Infections
D
G
R
S
L
View
254 32879304 N160A
Env
Env
HIV Infections
G
R
S
L
View
255 32879304 N332A
Env
Env
HIV Infections
D
G
R
S
L
View
256 32879304 R456W
Env
Env
HIV Infections
D
G
R
S
L
View
257 32879304 T676A
Env
Env
HIV Infections
D
G
R
S
L
View
258 32879304 W672L
Env
Env
HIV Infections
D
G
R
S
L
View
259 11581417 G429E
Env
Env
HIV Infections
G
R
S
C
L
T
View
260 11581417 K340E
Env
Env
HIV Infections
G
R
S
C
L
T
View
261 11581417 K350A
Env
Env
HIV Infections
G
R
S
C
L
T
View
262 33166562 L44M
Env
Env
HIV Infections
D
G
R
S
L
View
263 33166562 N126K
Env
Env
HIV Infections
D
G
R
S
L
View
264 33166562 R46K
Env
Env
HIV Infections
D
G
R
S
L
View
265 33166562 R46M
Env
Env
HIV Infections
D
G
R
S
L
View
266 33166562 R46Q
Env
Env
HIV Infections
D
G
R
S
L
View
267 33166562 S138A
Env
Env
HIV Infections
D
G
R
S
L
View
268 33253162 G458D
Env
Env
HIV Infections
D
G
I
View
269 33253162 N279K
Env
Env
HIV Infections
D
G
I
View
270 33253162 N280D
Env
Env
HIV Infections
D
G
I
View
271 33253162 R456W
Env
Env
HIV Infections
D
G
I
View
272 33290394 I181X
Env
Env
HIV Infections
D
G
I
C
L
View
273 33290394 K169X
Env
Env
HIV Infections
G
I
C
L
View
274 33515546 716insR*
Env
Env
HIV Infections
D
G
View
275 33515546 P203L
Env
Env
HIV Infections
D
G
View
276 33862046 H330Y
Env
Env
HIV Infections
D
G
L
View
277 33862046 Q328K
Env
Env
HIV Infections
D
G
L
View
278 33872329 K171E
Env
Env
HIV Infections
G
R
S
I
L
View
279 33872329 N156K
Env
Env
HIV Infections
G
R
S
I
L
View
280 33872329 R166G
Env
Env
HIV Infections
G
R
S
I
L
View
281 33872329 S640H
Env
Env
HIV Infections
G
R
S
I
L
View
Contents
Description

The table shows all curated mutation sites of HIV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.