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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19 Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	39616206	K14R	M	M	Cell line	S	View
2	39616206	K15R	M	M	Cell line	S	View
3	39616206	Q222A	M	M	Cell line	S	View
4	37637734	H163W	M	M	Cell line	D	View
5	37637734	H41M	M	M	Cell line		View
6	37637734	H41T	M	M	Cell line		View
7	37637734	H41Y	M	M	Cell line		View
8	37637734	E166A	M	M	Cell line	D	View
9	37637734	L167F	M	M	Cell line	D	View
10	37637734	E166H	M	M	Cell line	D	View
11	37637734	E166I	M	M	Cell line	D	View
12	37637734	E166K	M	M	Cell line	D	View
13	37637734	E166L	M	M	Cell line	D	View
14	37637734	E166Y	M	M	Cell line	D	View
15	37637734	E166Q	M	M	Cell line		View
16	37637734	H275Y	M	M	Cell line	D	View
17	37637734	S31N	M	M	Cell line	D	View
18	37637734	S144K	M	M	Cell line	D	View
19	37637734	S144P	M	M	Cell line	D	View
20	37637734	S144R	M	M	Cell line	D	View
21	37637734	H164N	M	M	Cell line		View
22	37637734	49delM	M	M	Cell line		View
23	37637734	Q189E	M	M	Cell line		View
24	37637734	M165A	M	M	Cell line		View
25	37637734	M165C	M	M	Cell line		View
26	37637734	M165I	M	M	Cell line		View
27	37637734	M165L	M	M	Cell line		View
28	37637734	M165V	M	M	Cell line		View
29	37637734	G15S	M	M	Cell line		View
30	37637734	K90R	M	M	Cell line		View
31	37637734	L205V	M	M	Cell line		View
32	37637734	L89F	M	M	Cell line		View
33	37637734	P108S	M	M	Cell line		View
34	37637734	P132H	M	M	Cell line		View
35	37637734	T21I	M	M	Cell line		View
36	37637734	S144L	M	M	Cell line		View
37	37637734	L50F	M	M	Cell line	D	View
38	37637734	S144D	M	M	Cell line	D	View
39	37637734	S144E	M	M	Cell line	D	View
40	37637734	S144H	M	M	Cell line	D	View
41	37637734	S144Q	M	M	Cell line	D	View
42	37637734	S144T	M	M	Cell line	D	View
43	37637734	S144V	M	M	Cell line	D	View
44	37637734	S144W	M	M	Cell line	D	View
45	37637734	H165Y	M	M	Cell line		View
46	37637734	T135I	M	M	Cell line		View
47	37637734	H172A	M	M	Cell line	D	View
48	37637734	H172Y	M	M	Cell line	D	View
49	37637734	M165Y	M	M	Cell line	D	View
50	37637734	M49I	M	M	Cell line		View
51	37637734	M49L	M	M	Cell line		View
52	37637734	M49T	M	M	Cell line		View
53	37637734	M49V	M	M	Cell line		View
54	37637734	H172C	M	M	Cell line		View
55	37637734	H172D	M	M	Cell line		View
56	37637734	H172E	M	M	Cell line		View
57	37637734	H172G	M	M	Cell line		View
58	37637734	H172I	M	M	Cell line		View
59	37637734	H172K	M	M	Cell line		View
60	37637734	H172L	M	M	Cell line		View
61	37637734	H172M	M	M	Cell line		View
62	37637734	H172N	M	M	Cell line		View
63	37637734	H172R	M	M	Cell line		View
64	37637734	H172S	M	M	Cell line		View
65	37637734	H172T	M	M	Cell line		View
66	37637734	H172V	M	M	Cell line		View
67	37637734	M165D	M	M	Cell line		View
68	37637734	M165F	M	M	Cell line		View
69	37637734	M165G	M	M	Cell line		View
70	37637734	M165H	M	M	Cell line		View
71	37637734	M165K	M	M	Cell line		View
72	37637734	M165P	M	M	Cell line		View
73	37637734	M165R	M	M	Cell line		View
74	37637734	M165W	M	M	Cell line		View
75	37637734	E166G	M	M	Cell line	D	View
76	37637734	E166V	M	M	Cell line	D	View
77	37637734	H172F	M	M	Cell line	D	View
78	37637734	H172Q	M	M	Cell line	D	View
79	37637734	M165T	M	M	Cell line	D	View
80	37637734	Q192A	M	M	Cell line	D	View
81	37637734	Q192C	M	M	Cell line	D	View
82	37637734	Q192F	M	M	Cell line	D	View
83	37637734	Q192H	M	M	Cell line	D	View
84	37637734	Q192I	M	M	Cell line	D	View
85	37637734	Q192L	M	M	Cell line	D	View
86	37637734	Q192P	M	M	Cell line	D	View
87	37637734	Q192S	M	M	Cell line	D	View
88	37637734	Q192T	M	M	Cell line	D	View
89	37637734	Q192V	M	M	Cell line	D	View
90	37637734	Q192W	M	M	Cell line	D	View
91	37637734	S144A	M	M	Cell line	D	View
92	37637734	S144F	M	M	Cell line	D	View
93	37637734	S144G	M	M	Cell line	D	View
94	37637734	S144M	M	M	Cell line	D	View
95	37637734	S144Y	M	M	Cell line	D	View
96	37637734	166delE	M	M	Cell line	D	View
97	37637734	164delH	M	M	Cell line	D	View
98	37637734	172delH	M	M	Cell line	D	View
99	37637734	165delM	M	M	Cell line	D	View
100	37637734	142delN	M	M	Cell line	D	View
101	37637734	189delQ	M	M	Cell line	D	View
102	37637734	192delQ	M	M	Cell line	D	View
103	37637734	144delS	M	M	Cell line	D	View
104	37637734	135delT	M	M	Cell line	D	View
105	39047088	T21I	M	M	Cell line	D R S	View
106	39047088	L50F	M	M	Cell line	D R S	View
107	39047088	P108S	M	M	Cell line	D R S	View
108	39047088	T135I	M	M	Cell line	D R S	View
109	39047088	F140L	M	M	Cell line	D R S	View
110	39047088	S144A	M	M	Cell line	D R S	View
111	39047088	C160F	M	M	Cell line	D R S	View
112	39047088	E166A	M	M	Cell line	D R S	View
113	39047088	E166V	M	M	Cell line	D R S	View
114	39047088	L167F	M	M	Cell line	D R S	View
115	39047088	T169I	M	M	Cell line	D R S	View
116	39047088	H172Y	M	M	Cell line	D R S	View
117	39047088	A173V	M	M	Cell line	D R S	View
118	39047088	V186A	M	M	Cell line	D R S	View
119	39047088	R188G	M	M	Cell line	D R S	View
120	39047088	A191V	M	M	Cell line	D R S	View
121	39047088	A193P	M	M	Cell line	D R S	View
122	39047088	P252L	M	M	Cell line	D R S	View
123	39047088	S301P	M	M	Cell line	D R S	View
124	39047088	T304I	M	M	Cell line	D R S	View
125	36539656	H125Y	M	M	Cell line	S L	View
126	37796123	A63T	M	M	COVID-19 Cell line	G R	View
127	37796123	Q19E	M	M	COVID-19 Cell line	G R	View
128	38731879	I82T	M	M		R	View
129	38731879	A63T	M	M		R	View
130	38731879	D3G	M	M		R	View
131	38731879	Q19E	M	M		R	View
132	37093365	D3G	M	M		G	View
133	37093365	Q19E	M	M		G	View
134	37093365	A63T	M	M		G	View
135	36537060	A26530G	M	M		G	View
136	36537060	G26709A	M	M		G	View
137	36537060	D3G	M	M		G	View
138	36537060	A63T	M	M		G	View
139	36537060	A27259C	M	M		G	View
140	35551247	I82T	M	M		G L	View
141	35733956	R44S	M	M		G R	View
142	36512569	G26730C	M	M		G R L	View
143	36512569	V70L	M	M		G R L	View
144	36548384	A2S	M	M		R L	View
145	36548384	A69S	M	M		R L	View
146	36548384	V70F	M	M		R L	View
147	36548384	M109I	M	M		R L	View
148	36548384	H155N	M	M		R L	View
149	36548384	H155Y	M	M		R L	View
150	36548384	Q185H	M	M		R L	View
151	36548384	I82T	M	M		R L	View
152	35798721	T7I	M	M		S	View
153	35966675	D3G	M	M	COVID-19	G R S C L	View
154	35966675	Q19E	M	M	COVID-19	G R S C L	View
155	35966675	A63T	M	M	COVID-19	G R S C L	View
156	36755883	Q19E	M	M	COVID-19	G R L	View
157	36755883	A63T	M	M	COVID-19	G R L	View
158	37737624	A26530G	M	M	COVID-19	G S L	View
159	37737624	A63T	M	M	COVID-19	G S L	View
160	37737624	C26577G	M	M	COVID-19	G S L	View
161	37737624	G26709A	M	M	COVID-19	G S L	View
162	37737624	Q19E	M	M	COVID-19	G S L	View
163	37737624	D3G	M	M	COVID-19	G S L	View
164	37965255	A63T	M	M	COVID-19	G R C L	View
165	37965255	D3N	M	M	COVID-19	G R C L	View
166	37965255	Q19E	M	M	COVID-19	G R C L	View
167	39416782	D3G	M	M	COVID-19	G L	View
168	39416782	D3N	M	M	COVID-19	G L	View
169	39416782	Q19E	M	M	COVID-19	G L	View
170	37275159	D3N	M	M	COVID-19	G R S C L	View
171	37275159	Q19E	M	M	COVID-19	G R S C L	View
172	35189404	C26681T	M	M	COVID-19	G R L	View
173	35189404	F53F	M	M	COVID-19	G R L	View
174	39015352	L50F	M	M	COVID-19	D G C L	View
175	39015352	I213V	M	M	COVID-19	D G C L	View
176	39015352	L227F	M	M	COVID-19	D G C L	View
177	36846745	N121N	M	M	COVID-19	G R S C L	View
178	36846745	F53F	M	M	COVID-19	G R S C L	View
179	35156767	I82T	M	M	COVID-19	G	View
180	35966675	I82T	M	M	COVID-19	G R S C L	View
181	35966679	I82T	M	M	COVID-19	G L	View
182	36590492	I82T	M	M	COVID-19	G R S L	View
183	36687433	I82T	M	M	COVID-19	G R S L	View
184	38435775	G79X	M	M	COVID-19	G C L	View
185	38435775	I82T	M	M	COVID-19	G C L	View
186	38435775	S197T	M	M	COVID-19	G C L	View
187	37243279	I82T	M	M	COVID-19	G R S C L	View
188	37243279	L29F	M	M	COVID-19	G R S C L	View
189	39015352	T21I	M	M	COVID-19	D G C L	View
190	39015352	K90R	M	M	COVID-19	D G C L	View
191	37744926	A27038G	M	M	COVID-19	G R S C L	View
192	37224159	C26577G	M	M	COVID-19	G R L	View
193	37224159	A26612T	M	M	COVID-19	G R L	View
194	37224159	G26709A	M	M	COVID-19	G R L	View
195	37224159	C26858T	M	M	COVID-19	G R L	View
196	37224159	A63T	M	M	COVID-19	G R L	View
197	37224159	F112F	M	M	COVID-19	G R L	View
198	37224159	Q19E	M	M	COVID-19	G R L	View
199	37224159	T30T	M	M	COVID-19	G R L	View
200	36755883	D3N	M	M	COVID-19	G R L	View
201	39227954	100delF	M	M	COVID-19	G R L	View
202	39227954	Q19E	M	M	COVID-19	G R L	View
203	39227954	99delS	M	M	COVID-19	G R L	View
204	37376693	A26530G	M	M	COVID-19	G R S L	View
205	34634791	I82T	M	M	COVID-19	G R S	View
206	34634791	I82S	M	M	COVID-19	G R S	View
207	33896413	I82T	M	M	COVID-19	G R L	View
208	35966679	F28L	M	M	COVID-19	G L	View
209	37573409	G26828T	M	M	COVID-19	G R S C L	View
210	40133357	C26645T	M	M	COVID-19	G R L	View
211	33896413	V70L	M	M	COVID-19	G R L	View
212	34125658	V70L	M	M	COVID-19	G R L	View
213	37243279	H210R	M	M	COVID-19	G R S C L	View
214	37243279	S212R	M	M	COVID-19	G R S C L	View
215	39015352	A191V	M	M	COVID-19	D G C L	View
216	39015352	P132H	M	M	COVID-19	D G C L	View
217	39015352	P108S	M	M	COVID-19	D G C L	View
218	35992703	E167K	M	M	COVID-19	G L	View
219	38601946	G26558T	M	M	COVID-19	G R C L	View
220	38601946	E12D	M	M	COVID-19	G R C L	View
221	38125422	A26530G	M	M	COVID-19	G R S C L	View
222	38125422	D3G	M	M	COVID-19	G R S C L	View
223	37849762	A63T	M	M	COVID-19	R S L	View
224	38605705	G26529A	M	M	COVID-19	G R S C L	View
225	38605705	C26577G	M	M	COVID-19	G R S C L	View
226	38605705	G26709A	M	M	COVID-19	G R S C L	View
227	38605705	C27012T	M	M	COVID-19	G R S C L	View
228	38605705	A27038G	M	M	COVID-19	G R S C L	View
229	38605705	D3N	M	M	COVID-19	G R S C L	View
230	38605705	Q19E	M	M	COVID-19	G R S C L	View
231	38605705	A63T	M	M	COVID-19	G R S C L	View
232	38632523	C26577G	M	M	COVID-19	G R L	View
233	38632523	G26709A	M	M	COVID-19	G R L	View
234	38632523	C26858T	M	M	COVID-19	G R L	View
235	38632523	Q19E	M	M	COVID-19	G R L	View
236	38632523	A63T	M	M	COVID-19	G R L	View
237	39294134	A188S	M	M	COVID-19	R S C L	View
238	39294134	I76T	M	M	COVID-19	R S C L	View
239	32595354	V10A	M	M	COVID-19	R L	View
240	36090111	F53F	M	M	COVID-19	R C L	View
241	36090111	I82T	M	M	COVID-19	R C L	View
242	36090111	L164L	M	M	COVID-19	R C L	View
243	36090111	V66V	M	M	COVID-19	R C L	View
244	36841805	A63T	M	M	COVID-19	R	View
245	36841805	I82T	M	M	COVID-19	R	View
246	36841805	Q19E	M	M	COVID-19	R	View
247	36672914	Q19E	M	M	COVID-19	C L	View
248	36672914	D3G	M	M	COVID-19	C L	View
249	36672914	A63T	M	M	COVID-19	C L	View
250	33384909	T175M	M	M	COVID-19	R	View
251	40143342	H125Y	M	M	COVID-19	R S L	View
252	40143342	I82T	M	M	COVID-19	R S L	View
253	40143342	K162N	M	M	COVID-19	R S L	View
254	40281619	Q19E	M	M	COVID-19	C L	View
255	35996593	H125Y	M	M	COVID-19	R L	View
256	36405589	Q19E	M	M	COVID-19	R S C L	View
257	36528612	D377Y	M	M	COVID-19	R	View
258	36528612	D63G	M	M	COVID-19	R	View
259	36528612	G215C	M	M	COVID-19	R	View
260	36528612	G204R	M	M	COVID-19	R	View
261	36528612	D3L	M	M	COVID-19	R	View
262	36528612	S235F	M	M	COVID-19	R	View
263	36528612	Q9L	M	M	COVID-19	R	View
264	36528612	A220V	M	M	COVID-19	R	View
265	36528612	P199L	M	M	COVID-19	R	View
266	36528612	G204P	M	M	COVID-19	R	View
267	36528612	V70L	M	M	COVID-19	R	View
268	36528612	A81S	M	M	COVID-19	R	View
269	36528612	F28L	M	M	COVID-19	R	View
270	36528612	S197N	M	M	COVID-19	R	View
271	36528612	T30I	M	M	COVID-19	R	View
272	36528612	I82T	M	M	COVID-19	R	View
273	36528612	D3G	M	M	COVID-19	R	View
274	36528612	A63T	M	M	COVID-19	R	View
275	36528612	Q19E	M	M	COVID-19	R	View
276	36528612	A2S	M	M	COVID-19	R	View
277	36841805	D3G	M	M	COVID-19	R	View
278	35707124	I24T	M	M	COVID-19	R L	View
279	35707124	L46F	M	M	COVID-19	R L	View
280	35759503	I82T	M	M	COVID-19	R L	View
281	35759503	T26767C	M	M	COVID-19	R L	View
282	35891618	L93L	M	M	COVID-19	S L	View
283	37903828	I82T	M	M	COVID-19	R L	View
284	37903828	L87F	M	M	COVID-19	R L	View
285	37903828	L29F	M	M	COVID-19	R L	View
286	37903828	A104V	M	M	COVID-19	R L	View
287	37903828	A69S	M	M	COVID-19	R L	View
288	37903828	H125Y	M	M	COVID-19	R L	View
289	37903828	V70F	M	M	COVID-19	R L	View
290	37903828	T175M	M	M	COVID-19	R L	View
291	37903828	D160Y	M	M	COVID-19	R	View
292	38348230	I82T	M	M	COVID-19	C L	View
293	36474565	I82T	M	M	COVID-19	R	View
294	36474565	A63T	M	M	COVID-19	R	View
295	36474565	F100I	M	M	COVID-19	R	View
296	36474565	Q19E	M	M	COVID-19	R	View
297	36474565	D3G	M	M	COVID-19	R	View
298	36474565	A2V	M	M	COVID-19	R	View
299	36474565	L16I	M	M	COVID-19	R	View
300	36474565	F28L	M	M	COVID-19	R	View
301	36474565	H155Y	M	M	COVID-19	R	View
302	36474565	V70I	M	M	COVID-19	R	View
303	36474565	S214I	M	M	COVID-19	R	View
304	36474565	L34F	M	M	COVID-19	R	View
305	36474565	I201V	M	M	COVID-19	R	View
306	36474565	H125Y	M	M	COVID-19	R	View
307	36474565	A69S	M	M	COVID-19	R	View
308	36474565	T30I	M	M	COVID-19	R	View
309	36474565	V70F	M	M	COVID-19	R	View
310	36474565	M1I	M	M	COVID-19	R	View
311	36474565	S4F	M	M	COVID-19	R	View
312	36474565	D209Y	M	M	COVID-19	R	View
313	36474565	E167D	M	M	COVID-19	R	View
314	36474565	M109I	M	M	COVID-19	R	View
315	36474565	L29F	M	M	COVID-19	R	View
316	36474565	T208I	M	M	COVID-19	R	View
317	36474565	A81S	M	M	COVID-19	R	View
318	36474565	G6V	M	M	COVID-19	R	View
319	36474565	A40S	M	M	COVID-19	R	View
320	32300673	T26729C	M	M	COVID-19	R	View
321	37529147	A63T	M	M	COVID-19	R S L	View
322	37529147	D163D	M	M	COVID-19	R S L	View
323	37529147	F112F	M	M	COVID-19	R S L	View
324	37529147	Q19E	M	M	COVID-19	R S L	View
325	40006937	I82T	M	M	COVID-19	S L	View
326	40006937	T26767C	M	M	COVID-19	S L	View
327	34125658	I82T	M	M	COVID-19	L	View
328	35208920	I82T	M	M	COVID-19	R L	View
329	32816316	D3G	M	M	COVID-19	R L	View
330	32937868	C27046T	M	M	COVID-19	R L	View
331	32937868	T175M	M	M	COVID-19	R L	View
332	33163695	A2V	M	M	COVID-19	R L	View
333	33163695	H125Y	M	M	COVID-19	R L	View
334	34938188	C145A	M	M	COVID-19		View
335	39015352	C16S	M	M	COVID-19	C L	View
336	39015352	L32F	M	M	COVID-19	C L	View
337	39015352	V91D	M	M	COVID-19	C L	View
338	39015352	V91I	M	M	COVID-19	C L	View
339	39015352	N95A	M	M	COVID-19	C L	View
340	39015352	G143D	M	M	COVID-19	C L	View
341	39015352	V157W	M	M	COVID-19	C L	View
342	39015352	F159S	M	M	COVID-19	C L	View
343	39015352	M162I	M	M	COVID-19	C L	View
344	39015352	V171D	M	M	COVID-19	C L	View
345	39015352	G174S	M	M	COVID-19	C L	View
346	39015352	D176S	M	M	COVID-19	C L	View
347	39015352	L177S	M	M	COVID-19	C L	View
348	39015352	E178W	M	M	COVID-19	C L	View
349	39015352	F181T	M	M	COVID-19	C L	View
350	39015352	Y182N	M	M	COVID-19	C L	View
351	39015352	A234V	M	M	COVID-19	C L	View
352	39015352	H246R	M	M	COVID-19	C L	View
353	39015352	D263Y	M	M	COVID-19	C L	View
354	39015352	G278R	M	M	COVID-19	C L	View
355	39015352	R279C	M	M	COVID-19	C L	View
356	39015352	T280A	M	M	COVID-19	C L	View
357	39015352	G283D	M	M	COVID-19	C L	View
358	38668234	Y71Y	M	M	COVID-19	R C L	View
359	38668234	I82T	M	M	COVID-19	R C L	View
360	36343703	C26735T	M	M	COVID-19	R	View
361	32595354	C26735T	M	M	COVID-19	R L	View
362	32595354	C26549T	M	M	COVID-19	R L	View
363	32595354	G26720C	M	M	COVID-19	R L	View
364	32595354	T26551C	M	M	COVID-19	R L	View
365	39660912	A63T	M	M	Cell line	G	View
366	39660912	D3G	M	M	Cell line	G	View
367	39660912	Q19E	M	M	Cell line	G	View