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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19 Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	37487098	S676T	NSP3	ORF1a	Cell line		View
2	39048693	I541V	NSP3	ORF1a	Cell line	R L	View
3	39048693	S1087F	NSP3	ORF1a	Cell line	R L	View
4	39048693	I1489T	NSP3	ORF1a	Cell line	R L	View
5	39048693	S1717L	NSP3	ORF1a	Cell line	R L	View
6	39048693	H1841Y	NSP3	ORF1a	Cell line	R L	View
7	39048693	A4340G	NSP3	ORF1a	Cell line	R L	View
8	39048693	C5979T	NSP3	ORF1a	Cell line	R L	View
9	39048693	T7185C	NSP3	ORF1a	Cell line	R L	View
10	39048693	C7869T	NSP3	ORF1a	Cell line	R L	View
11	39048693	C8240T	NSP3	ORF1a	Cell line	R L	View
12	36852863	C52562G	NSP3	ORF1a	Cell line		View
13	36539656	N1543K	NSP3	ORF1a	Cell line	S L	View
14	36539656	M1788I	NSP3	ORF1a	Cell line	S L	View
15	36852863	S848C	NSP3	ORF1a	Cell line		View
16	37651466	N40A	NSP3	ORF1a	COVID-19 Cell line		View
17	37651466	N40D	NSP3	ORF1a	COVID-19 Cell line		View
18	38415690	A54T	NSP3	ORF1a	COVID-19 Cell line	G R S	View
19	38792736	N1329D	NSP3	ORF1a		G R L	View
20	38792736	Q180H	NSP3	ORF1a		G R L	View
21	39584063	C3037T	NSP3	ORF1a		R	View
22	35745660	A1892T	NSP3	ORF1a		G	View
23	35745660	K38R	NSP3	ORF1a		G	View
24	35745660	L1266I	NSP3	ORF1a		G	View
25	35745660	V1069I	NSP3	ORF1a		G	View
26	35733956	A99S	NSP3	ORF1a		G R	View
27	35733956	L98F	NSP3	ORF1a		G R	View
28	35733956	L98I	NSP3	ORF1a		G R	View
29	35733956	T1456I	NSP3	ORF1a		G R	View
30	35733956	V477F	NSP3	ORF1a		G R	View
31	36512569	C5388A	NSP3	ORF1a		G R L	View
32	36512569	C3267T	NSP3	ORF1a		G R L	View
33	36512569	C3037T	NSP3	ORF1a		G R L	View
34	36512569	C5986T	NSP3	ORF1a		G R L	View
35	36512569	T6954C	NSP3	ORF1a		G R L	View
36	36512569	C3177T	NSP3	ORF1a		G R L	View
37	36512569	G8179A	NSP3	ORF1a		G R L	View
38	36512569	C3096T	NSP3	ORF1a		G R L	View
39	36512569	G4255A	NSP3	ORF1a		G R L	View
40	36512569	G7272A	NSP3	ORF1a		G R L	View
41	36512569	C8290T	NSP3	ORF1a		G R L	View
42	36512569	A890D	NSP3	ORF1a		G R L	View
43	36512569	T183I	NSP3	ORF1a		G R L	View
44	36512569	F106F	NSP3	ORF1a		G R L	View
45	36512569	F1089F	NSP3	ORF1a		G R L	View
46	36512569	I1412T	NSP3	ORF1a		G R L	View
47	36512569	P153L	NSP3	ORF1a		G R L	View
48	36512569	R1820R	NSP3	ORF1a		G R L	View
49	36512569	S126L	NSP3	ORF1a		G R L	View
50	36512569	P512P	NSP3	ORF1a		G R L	View
51	36512569	R1518K	NSP3	ORF1a		G R L	View
52	36512569	L1857L	NSP3	ORF1a		G R L	View
53	35624123	C7303T	NSP3	ORF1a		R	View
54	35624123	L1035F	NSP3	ORF1a		R	View
55	35547225	A1708D	NSP3	ORF1a		S L	View
56	35547225	I2230T	NSP3	ORF1a		S L	View
57	35547225	T1001I	NSP3	ORF1a		S L	View
58	35706980	D1639N	NSP3	ORF1a		S C L	View
59	35706980	G5180A	NSP3	ORF1a		S C L	View
60	35745660	V1096I	NSP3	ORF1a			View
61	36686884	D1047D	NSP3	ORF1a		R L	View
62	36686884	D1047V	NSP3	ORF1a		R L	View
63	36686884	T1797S	NSP3	ORF1a		R L	View
64	36686884	T1797T	NSP3	ORF1a		R L	View
65	36686884	V1885A	NSP3	ORF1a		R L	View
66	35617193	E45V	NSP3	ORF1a		S L	View
67	35617193	V256D	NSP3	ORF1a		S L	View
68	35617193	W128M	NSP3	ORF1a		S L	View
69	38476954	F106F	NSP3	ORF1a	COVID-19	G R S L	View
70	38476954	P314L	NSP3	ORF1a	COVID-19	G R S L	View
71	33391880	P679S	NSP3	ORF1a	COVID-19	G R S L	View
72	33391880	P822L	NSP3	ORF1a	COVID-19	G R S L	View
73	34399188	A328T	NSP3	ORF1a	COVID-19	G	View
74	35966679	A488S	NSP3	ORF1a	COVID-19	G L	View
75	35966679	V932A	NSP3	ORF1a	COVID-19	G L	View
76	35966679	P1228L	NSP3	ORF1a	COVID-19	G L	View
77	35966679	P1469S	NSP3	ORF1a	COVID-19	G L	View
78	36590492	A488S	NSP3	ORF1a	COVID-19	G R S L	View
79	36590492	P1228L	NSP3	ORF1a	COVID-19	G R S L	View
80	36590492	P1469S	NSP3	ORF1a	COVID-19	G R S L	View
81	36590492	L1511V	NSP3	ORF1a	COVID-19	G R S L	View
82	36590492	A1711V	NSP3	ORF1a	COVID-19	G R S L	View
83	36590492	P1867T	NSP3	ORF1a	COVID-19	G R S L	View
84	36786950	F1469S	NSP3	ORF1a	COVID-19	G R S C L	View
85	36786950	F1569V	NSP3	ORF1a	COVID-19	G R S C L	View
86	36786950	T248I	NSP3	ORF1a	COVID-19	G R S C L	View
87	37224159	T64T	ORF3a;NSP3	ORF3a;ORF1a	COVID-19	G R L	View
88	37224159	T2911C	NSP3;ORF3	ORF1a;ORF3a	COVID-19	G R L	View
89	37224159	T24I	NSP3;N	ORF1a;N	COVID-19	G R L	View
90	37224159	C28344T	NSP3	ORF1a	COVID-19	G R L	View
91	37224159	C3037T	NSP3	ORF1a	COVID-19	G R L	View
92	37224159	C3796T	NSP3	ORF1a	COVID-19	G R L	View
93	37224159	C3927T	NSP3	ORF1a	COVID-19	G R L	View
94	37224159	G4184A	NSP3	ORF1a	COVID-19	G R L	View
95	37224159	C4321T	NSP3	ORF1a	COVID-19	G R L	View
96	37224159	C4586T	NSP3	ORF1a	COVID-19	G R L	View
97	37224159	C5183T	NSP3	ORF1a	COVID-19	G R L	View
98	37224159	A534A	NSP3	ORF1a	COVID-19	G R L	View
99	37224159	D622D	NSP3	ORF1a	COVID-19	G R L	View
100	37224159	F106F	NSP3	ORF1a	COVID-19	G R L	View
101	37224159	G489S	NSP3	ORF1a	COVID-19	G R L	View
102	37224159	P822S	NSP3	ORF1a	COVID-19	G R L	View
103	37224159	S403L	NSP3	ORF1a	COVID-19	G R L	View
104	37224159	T183I	NSP3	ORF1a	COVID-19	G R L	View
105	37224159	T241I	NSP3	ORF1a	COVID-19	G R L	View
106	37224159	V359V	NSP3	ORF1a	COVID-19	G R L	View
107	33253226	C6310A	NSP3	ORF1a	COVID-19	G S L	View
108	37799539	A58T	NSP3	ORF1a	COVID-19	G R C L	View
109	34424256	D455N	NSP3	ORF1a	COVID-19	G S L	View
110	34424256	N844S	NSP3	ORF1a	COVID-19	G S L	View
111	35966679	S543P	NSP3	ORF1a	COVID-19	G L	View
112	36778569	L761I	NSP3	ORF1a	COVID-19	G R S L	View
113	36029839	C3037T	NSP3	ORF1a	COVID-19	G R S C L	View
114	39604601	A231Y	NSP3	ORF1a	COVID-19	G L	View
115	39604601	H1467Y	NSP3	ORF1a	COVID-19	G L	View
116	35996593	K977Q	NSP3	ORF1a	COVID-19	G R L	View
117	35992703	C5239T	NSP3	ORF1a	COVID-19	G R L	View
118	35992703	T5514C	NSP3	ORF1a	COVID-19	G R L	View
119	35992703	V932A	NSP3	ORF1a	COVID-19	G R L	View
120	35992703	Y840Y	NSP3	ORF1a	COVID-19	G R L	View
121	35992703	P402T	NSP3	ORF1a	COVID-19	G L	View
122	35992703	N873D	NSP3	ORF1a	COVID-19	G L	View
123	35992703	A1537S	NSP3	ORF1a	COVID-19	G L	View
124	35992703	I1413F	NSP3	ORF1a	COVID-19	G L	View
125	35992703	N1284S	NSP3	ORF1a	COVID-19	G L	View
126	35992703	V61I	NSP3	ORF1a	COVID-19	G L	View
127	35992703	Y1185C	NSP3	ORF1a	COVID-19	G L	View
128	35992703	N444S	NSP3	ORF1a	COVID-19	G L	View
129	35992703	G250V	NSP3	ORF1a	COVID-19	G L	View
130	35992703	S1682F	NSP3	ORF1a	COVID-19	G L	View
131	35992703	T182I	NSP3	ORF1a	COVID-19	G L	View
132	35992703	T350I	NSP3	ORF1a	COVID-19	G L	View
133	35992703	N1587D	NSP3	ORF1a	COVID-19	G L	View
134	35992703	T199I	NSP3	ORF1a	COVID-19	G L	View
135	35996593	P822L	NSP3	ORF1a	COVID-19	G R L	View
136	35605880	T183I	NSP3	ORF1a	COVID-19	G R L	View
137	35966679	T183I	NSP3	ORF1a	COVID-19	G L	View
138	35966679	A890D	NSP3	ORF1a	COVID-19	G L	View
139	35966679	I1412T	NSP3	ORF1a	COVID-19	G L	View
140	32742035	C3037T	NSP3	ORF1a	COVID-19	R	View
141	32742035	A58T	NSP3	ORF1a	COVID-19	R	View
142	32742035	P153L	NSP3	ORF1a	COVID-19	R	View
143	32742035	T85I	NSP3	ORF1a	COVID-19	R	View
144	38791536	Q1821R	NSP3	ORF1a	COVID-19	R L	View
145	37630656	T820N	NSP3	ORF1a	COVID-19	G R S C	View
146	38605705	C2790T	NSP3	ORF1a	COVID-19	G R S C L	View
147	38605705	C3037T	NSP3	ORF1a	COVID-19	G R S C L	View
148	38605705	G4184A	NSP3	ORF1a	COVID-19	G R S C L	View
149	38605705	C4321T	NSP3	ORF1a	COVID-19	G R S C L	View
150	38605705	C6402T	NSP3	ORF1a	COVID-19	G R S C L	View
151	38605705	C7029T	NSP3	ORF1a	COVID-19	G R S C L	View
152	38605705	C7528T	NSP3	ORF1a	COVID-19	G R S C L	View
153	38605705	T24I	NSP3	ORF1a	COVID-19	G R S C L	View
154	38605705	G489S	NSP3	ORF1a	COVID-19	G R S C L	View
155	38605705	P1228L	NSP3	ORF1a	COVID-19	G R S C L	View
156	38605705	S1437F	NSP3	ORF1a	COVID-19	G R S C L	View
157	34305826	T987N	NSP3	ORF1a	COVID-19	R L	View
158	32595352	C3037T	NSP3	ORF1a	COVID-19	R	View
159	35996593	T504P	NSP3	ORF1a	COVID-19	R L	View
160	35996593	T820I	NSP3	ORF1a	COVID-19	R L	View
161	36008511	P2110S	NSP3	ORF1a	COVID-19	R C L	View
162	36008511	A859V	NSP3	ORF1a	COVID-19	R C L	View
163	36008511	D1639N	NSP3	ORF1a	COVID-19	R C L	View
164	36008511	M1312I	NSP3	ORF1a	COVID-19	R C L	View
165	36008511	S2625F	NSP3	ORF1a	COVID-19	R C L	View
166	36008511	T1246I	NSP3	ORF1a	COVID-19	R C L	View
167	36090111	A1306S	NSP3	ORF1a	COVID-19	R C L	View
168	36090111	A1708D	NSP3	ORF1a	COVID-19	R C L	View
169	36090111	F1907F	NSP3	ORF1a	COVID-19	R C L	View
170	36090111	F924F	NSP3	ORF1a	COVID-19	R C L	View
171	36090111	I2230T	NSP3	ORF1a	COVID-19	R C L	View
172	36090111	K798K	NSP3	ORF1a	COVID-19	R C L	View
173	36090111	L2062F	NSP3	ORF1a	COVID-19	R C L	View
174	36090111	L733L	NSP3	ORF1a	COVID-19	R C L	View
175	36090111	M2365I	NSP3	ORF1a	COVID-19	R C L	View
176	36090111	P1640L	NSP3	ORF1a	COVID-19	R C L	View
177	36090111	P2046L	NSP3	ORF1a	COVID-19	R C L	View
178	36090111	P2287S	NSP3	ORF1a	COVID-19	R C L	View
179	36090111	T1001I	NSP3	ORF1a	COVID-19	R C L	View
180	36090111	T1773T	NSP3	ORF1a	COVID-19	R C L	View
181	36090111	T2007I	NSP3	ORF1a	COVID-19	R C L	View
182	36687433	Q191R	NSP3	ORF1a	COVID-19	R S L	View
183	36841805	P1228L	NSP3	ORF1a	COVID-19	R	View
184	35614572	D178Y	NSP3	ORF1a	COVID-19	R	View
185	35707124	P822L	NSP3	ORF1a	COVID-19	R L	View
186	35707124	Q57H	NSP3	ORF1a	COVID-19	R L	View
187	35707124	S126L	NSP3	ORF1a	COVID-19	R L	View
188	35707124	T350I	NSP3	ORF1a	COVID-19	R L	View
189	35759503	C3037T	NSP3	ORF1a	COVID-19	R L	View
190	35759503	P2046L	NSP3	ORF1a	COVID-19	R L	View
191	35759503	P2287S	NSP3	ORF1a	COVID-19	R L	View
192	35913920	G251V	NSP3	ORF1a	COVID-19	R	View
193	35913920	Q57H	NSP3	ORF1a	COVID-19	R	View
194	35913920	T1198K	NSP3	ORF1a	COVID-19	R	View
195	32972934	P822S	NSP3	ORF1a	COVID-19	S L	View
196	32972934	Q172R	NSP3	ORF1a	COVID-19	S L	View
197	33049387	S1498F	NSP3	ORF1a	COVID-19	I	View
198	33384909	D2101G	NSP3	ORF1a	COVID-19	R	View
199	33384909	D953Y	NSP3	ORF1a	COVID-19	R	View
200	33384909	H1113Y	NSP3	ORF1a	COVID-19	R	View
201	33384909	I1508V	NSP3	ORF1a	COVID-19	R	View
202	33384909	K1202N	NSP3	ORF1a	COVID-19	R	View
203	33384909	M1588K	NSP3	ORF1a	COVID-19	R	View
204	33384909	P1096L	NSP3	ORF1a	COVID-19	R	View
205	33384909	V1052I	NSP3	ORF1a	COVID-19	R	View
206	35891618	F106F	NSP3	ORF1a	COVID-19	S L	View
207	35891618	N291Y	NSP3	ORF1a	COVID-19	S L	View
208	38791536	W1190C	NSP3	ORF1a	COVID-19	R L	View
209	38791536	G1822R	NSP3	ORF1a	COVID-19	R L	View
210	38348230	E391G	NSP3	ORF1a	COVID-19	C L	View
211	36672914	L1266I	NSP3	ORF1a	COVID-19	C L	View
212	36672914	A1892T	NSP3	ORF1a	COVID-19	C L	View
213	37260697	C3037T	NSP3	ORF1a	COVID-19	R S C L	View
214	37260697	C421T	NSP3	ORF1a	COVID-19	R S C L	View
215	37260697	P141S	NSP3	ORF1a	COVID-19	R S C L	View
216	37529147	A534A	NSP3	ORF1a	COVID-19	R S L	View
217	37529147	F106F	NSP3	ORF1a	COVID-19	R S L	View
218	37529147	K977K	NSP3	ORF1a	COVID-19	R S L	View
219	37529147	L1791L	NSP3	ORF1a	COVID-19	R S L	View
220	37529147	T24I	NSP3	ORF1a	COVID-19	R S L	View
221	37529147	Y828Y	NSP3	ORF1a	COVID-19	R S L	View
222	39294134	N1369S	NSP3	ORF1a	COVID-19	R S C L	View
223	39294134	R568C	NSP3	ORF1a	COVID-19	R S C L	View
224	39294134	S454R	NSP3	ORF1a	COVID-19	R S C L	View
225	39294134	V573I	NSP3	ORF1a	COVID-19	R S C L	View
226	40006937	C3037T	NSP3	ORF1a	COVID-19	S L	View
227	40084424	C3037T	NSP3	ORF1a	COVID-19	R S L	View
228	33558859	L431H	NSP3	ORF1a	COVID-19	R L	View
229	33622851	T1103P	NSP3	ORF1a	COVID-19	R	View
230	33797663	V843F	NSP3	ORF1a	COVID-19	S L	View
231	33797663	A889V	NSP3	ORF1a	COVID-19	S L	View
232	33797663	G1691C	NSP3	ORF1a	COVID-19	S L	View
233	33932525	E1363D	NSP3	ORF1a	COVID-19	R C L	View
234	35208920	T428I	NSP3	ORF1a	COVID-19	R L	View
235	32793182	C3037T	NSP3	ORF1a	COVID-19	R	View
236	32793182	C14805T	NSP3	ORF1a	COVID-19	R	View
237	33184173	C3037T	NSP3	ORF1a	COVID-19		View
238	33184173	C3730T	NSP3	ORF1a	COVID-19		View
239	33357233	T1198I	NSP3	ORF1a	COVID-19	R	View
240	33357233	T1198K	NSP3	ORF1a	COVID-19	R	View
241	33357233	T1198R	NSP3	ORF1a	COVID-19	R	View
242	34468954	D218E	NSP3	ORF1a	COVID-19	R C L	View
243	36819024	V1762F	NSP3	ORF1a	COVID-19	L	View
244	36819024	K412N	NSP3	ORF1a	COVID-19	L	View
245	38668234	F106F	NSP3	ORF1a	COVID-19	R C L	View
246	38483913	P822L	NSP3	ORF1a	COVID-19	L	View
247	38435775	T6I	NSP3	ORF1a	COVID-19	C L	View
248	38435775	T48I	NSP3	ORF1a	COVID-19	C L	View
249	38435775	T183I	NSP3	ORF1a	COVID-19	C L	View
250	38435775	E130D	NSP3	ORF1a	COVID-19	C L	View
251	38435775	A488S	NSP3	ORF1a	COVID-19	C L	View
252	38435775	G489S	NSP3	ORF1a	COVID-19	C L	View
253	38435775	T725I	NSP3	ORF1a	COVID-19	C L	View
254	38435775	A890D	NSP3	ORF1a	COVID-19	C L	View
255	38435775	A1006V	NSP3	ORF1a	COVID-19	C L	View
256	38435775	A1105T	NSP3	ORF1a	COVID-19	C L	View
257	38435775	P1228L	NSP3	ORF1a	COVID-19	C L	View
258	38435775	I1412T	NSP3	ORF1a	COVID-19	C L	View
259	38435775	C1421F	NSP3	ORF1a	COVID-19	C L	View
260	38435775	P1469S	NSP3	ORF1a	COVID-19	C L	View
261	38435775	S1682F	NSP3	ORF1a	COVID-19	C L	View
262	38435775	A1775V	NSP3	ORF1a	COVID-19	C L	View
263	36786950	E419A	NSP3	ORF1a	COVID-19	R S C L	View
264	32515358	C3037T	NSP3	ORF1a	COVID-19	R L	View
265	32515358	C7945T	NSP3	ORF1a	COVID-19	R L	View
266	32595354	A1006V	NSP3	ORF1a	COVID-19	R L	View
267	32780783	C3037T	NSP3	ORF1a	COVID-19	R	View