Gene Name	BIRC3
Gene ID	330
Gene Full Name	baculoviral IAP repeat containing 3
Gene Alias	AIP1|API2|CIAP2|HAIP1|HIAP1|IAP-1|MALT2|MIHC|RNF49|c-IAP2
Transcripts	ENSG00000023445
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm, Cytosol;
Membrane Info	Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q13489
HGNC ID	HGNC:591
OMIM ID	601721
Summary	This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5000032	chr11	1915	2819	1738	6472	View
5000033	chr11	1834	2860	1770	6464	View
5000036	chr11	1665	2878	1787	6330	View
5001034	chr11	6	47	4	57	View
5001043	chr11	34	18	4	56	View
5001555	chr11	20	9	0	29	View
5001585	chr11	25	3	0	28	View
5001657	chr11	25	1	0	26	View
5001738	chr11	23	1	0	24	View
5001852	chr11	19	2	0	21	View
5002157	chr11	9	4	2	15	View
5002400	chr11	12	0	0	12	View
5002401	chr11	12	0	0	12	View

Data ID	Experiment type	Sample number	Platform
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
S   GSE197461	scRNA-seq	16	Illumina NovaSeq 6000 (Homo sapiens)
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE199029	Variation;RNA-seq	44	NanoString Human nCounter PanCancer IO360 Panel
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
S   GSE226620	scRNA-seq	30	HiSeq X Ten (Homo sapiens)
GSE40774	Expression array	134	Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
S   GSE139324	scRNA-seq	63	Illumina NextSeq 500 (Homo sapiens)
GSE138080	Expression array	35	Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
S   GSE164690	scRNA-seq	51	Illumina NextSeq 500 (Homo sapiens)
E   GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA

• Expression profiling
• scRNA data
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE55542 - BIRC3 expression across samples

Volcano Plot

Bar Plot