HPV Target gene Detail Information

> MYC Gene Search Result


Gene Information
Gene Name MYC
Gene ID 4609
Gene Full Name MYC proto-oncogene, bHLH transcription factor
Gene Alias MRTL|MYCC|bHLHe39|c-Myc
Transcripts ENSG00000136997
Virus HPV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID P01106
HGNC ID HGNC:7553
OMIM ID 190080
Summary This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Target gene [MYC] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000040 chr8 5120 4950 1740 11810 View
5000205 chr8 91 375 144 610 View
5000211 chr8 126 259 199 584 View
5000337 chr8 126 26 141 293 View
5001589 chr8 8 18 2 28 View
5007417 chr8 205 8 0 213 View
5007538 chr8 132 22 0 154 View
5007539 chr8 221 17 0 238 View
5007587 chr8 196 10 0 206 View
5013785 chr8 2730 334 20 3084 View
5013786 chr8 1813 328 144 2285 View
5013787 chr8 265 1012 167 1444 View
5013788 chr8 148 72 22 242 View
5013789 chr8 245 14 40 299 View
5013790 chr8 250 14 40 304 View
5013791 chr8 262 15 40 317 View
5013792 chr8 582 124 139 845 View
5013793 chr8 581 76 34 691 View
5013796 chr8 2048 1731 974 4753 View
5013800 chr8 3730 1162 478 5370 View
5013804 chr8 2431 391 70 2892 View
5013813 chr8 647 157 86 890 View
5013817 chr8 614 48 160 822 View
5016383 chr8 266 26 0 292 View
5016384 chr8 406 366 224 996 View
5017799 chr8 20 111 80 211 View
5017800 chr8 20 111 80 211 View
5017801 chr8 86 10 0 96 View
5017802 chr8 1 7 0 8 View
5017803 chr8 117 158 27 302 View
5017804 chr8 2 13 5 20 View
5017808 chr8 1863 696 769 3328 View
5017809 chr8 114 16 24 154 View
5017810 chr8 25 15 0 40 View

Target gene [MYC] related to Omics data
Data ID Experiment type Sample number Platform
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
S
  GSE197461 		scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
GSE55550 Expression array 155 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE199029 Variation;RNA-seq 44 NanoString Human nCounter PanCancer IO360 Panel
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)
C
  GSE183048 		Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
S
  GSE226620 		scRNA-seq 30 HiSeq X Ten (Homo sapiens)
GSE40774 Expression array 134 Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE139324 scRNA-seq 63 Illumina NextSeq 500 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
S
  GSE164690 		scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE55542 Expression array 36 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA


When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.


> Dataset: GSE197461 - Gene expression in cell subsets

> Dataset: GSE226620 - Gene expression in cell subsets

> Dataset: GSE164690 - Gene expression in cell subsets