Gene Information
|
Gene Name
|
SKIC2 |
|
Gene ID
|
6499
|
|
Gene Full Name
|
SKI2 subunit of superkiller complex |
|
Gene Alias
|
170A|DDX13|HLP|SKI2|SKI2W|SKIV2|SKIV2L|SKIV2L1|THES2 |
|
Transcripts
|
ENSG00000204351
|
|
Virus
|
HIV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nuclear bodies;Mitotic spindle, Cytosol; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
Q15477
|
|
HGNC ID
|
HGNC:10898
|
|
OMIM ID
|
600478 |
|
Summary
|
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008] |
Target gene [SKIC2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 4003339 |
chr6 |
65 |
6 |
0 |
71 |
View |
Target gene [SKIC2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE220859
|
Chip-seq |
11 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE128121
|
RNA-seq |
16 |
Illumina HiSeq 4000 (Homo sapiens) |
|
C GSE211651
|
Chip-seq;RNA-seq;PRO-seq |
39 |
Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE162914
|
RNA-seq |
211 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE221688
|
Chip-seq;scATAC-Seq;scRNA-Seq |
12 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E GSE144332
|
RNA-seq |
75 |
NextSeq 550 (Homo sapiens) |
|
C GSE100376
|
ATAC-seq |
24 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE165705
|
Chip-seq |
30 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE165703
|
ATAC-seq |
82 |
Illumina HiSeq 4000 (Homo sapiens) |
|
C GSE144329
|
ATAC-seq |
96 |
NextSeq 550 (Homo sapiens) |
|
GSE205204
|
RNA-seq |
14 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE167211
|
RNA-seq |
1 |
Illumina HiSeq 2000 (Homo sapiens) |
|
GSE246082
|
RNA-seq |
6 |
Illumina HiSeq 4000 (Homo sapiens) |
|
C GSE100266
|
ATAC-seq;Chip-seq;RNA-seq |
32 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE125686
|
RNA-seq |
62 |
Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
|
GSE164264
|
RNA-seq |
6 |
BGISEQ-500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE144332 - SKIC2 expression across samples
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Volcano Plot
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Bar Plot
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HIV Target gene Detail Information
