Gene Name	SSTR3
Gene ID	6753
Gene Full Name	somatostatin receptor 3
Gene Alias	SS-3-R|SS3-R|SS3R|SSR-28|SST3
Transcripts	ENSG00000278195
Virus	HIV
Gene Type	protein-coding
HPA Location Info	Primary cilium;Cytosol;
Membrane Info	FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters
Uniport_ID	P32745
HGNC ID	HGNC:11332
OMIM ID	182453
Summary	This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009691	chr22	9	1	1	11	View

Data ID	Experiment type	Sample number	Platform
GSE262621	RNA-seq	70	Illumina NovaSeq 6000 (Homo sapiens)
GSE165708	RNA-seq	100	Illumina HiSeq 4000 (Homo sapiens)
C   GSE211651	Chip-seq;RNA-seq;PRO-seq	39	Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE162914	RNA-seq	211	Illumina HiSeq 2500 (Homo sapiens)
GSE99737	RNA-seq	9	Illumina HiSeq 2500 (Homo sapiens)
GSE144332	RNA-seq	75	NextSeq 550 (Homo sapiens)
GSE68028	MeDIP-chip	1	NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
GSE279982	Methylation profiling (Array)	576	Infinium MethylationEPIC
C   GSE165705	Chip-seq	30	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE144329	ATAC-seq	96	NextSeq 550 (Homo sapiens)
GSE205204	RNA-seq	14	Illumina NovaSeq 6000 (Homo sapiens)
GSE246082	RNA-seq	6	Illumina HiSeq 4000 (Homo sapiens)
C   GSE100266	ATAC-seq;Chip-seq;RNA-seq	32	Illumina HiSeq 2500 (Homo sapiens)
GSE125686	RNA-seq	62	Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE164264	RNA-seq	6	BGISEQ-500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE211651 - SSTR3 peak across samples

Peak Plot

> Dataset: GSE165705 - SSTR3 peak across samples

Peak Plot

> Dataset: GSE144329 - SSTR3 peak across samples

Peak Plot

> Dataset: GSE100266 - SSTR3 peak across samples

Peak Plot